The prognostic value of serum testosterone to BMI ratio in Chinese males with prostate cancer treated by androgen deprivation therapy: a single-center study

International Urology and Nephrology, Год журнала: 2025, Номер unknown

Опубликована: Янв. 7, 2025

Язык: Английский

---

The Molecular Basis of Love

International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(4), С. 1533 - 1533

Опубликована: Фев. 12, 2025

Love as a complex interplay of emotions and behaviors is underpinned by an intricate network neurobiological mechanisms. This review provides insight into the molecular basis love, focusing on role key hormones neuromodulators. The aim paper to report how these biochemical messengers influence various aspects including attraction, attachment, long-term bonding. By examining effects such dopamine, oxytocin, vasopressin, serotonin, we elucidate relationship between biology behavior. Additionally, potential impact modern lifestyle factors hormonal balance their subsequent love social interactions are outlined. useful overview underpinnings offering insights biological mechanisms that shape human relationships.

Язык: Английский

---

Association between the oxidative balance score and testosterone deficiency: a cross-sectional study of the NHANES, 2011–2016

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Март 7, 2025

There is increasing recognition of the role oxidative balance in testosterone deficiency (TD). This study investigates association between score (OBS) and TD prevalence among adult males United States. Data were obtained from a cross-sectional 3276 men 2011–2016 National Health Nutrition Examination Survey. OBS was assessed based on 16 nutrient 4 lifestyle components. Multivariate logistic regression subgroup analyses conducted to calculate odds ratios (OR) 95% confidence intervals (CI) for prevalence. After adjusting potential confounders, negative linear observed (OR = 0.98, CI 0.97–1.00). Participants highest tertile had lower compared those lowest 0.92, 0.69–1.21). Lifestyle components significantly associated with 0.85, 0.81–0.90). Furthermore, least absolute shrinkage selection operator identified key most strongly TD, physical activity exerting greatest influence. A predictive nomogram model incorporating these demonstrated discriminatory power an area under curve 0.744 (95% 72.4–76.4%). In conclusion, this demonstrates inverse prevalence, suggesting regulation US males.

Язык: Английский

---

Initiating Testosterone Therapy Without Indication for Treatment of Low Testosterone Is Associated With Higher Risk of Tendon Tear

Sports Health A Multidisciplinary Approach, Год журнала: 2025, Номер unknown

Опубликована: Апрель 28, 2025

Background: Studies have demonstrated an increasing rate of testosterone supplementation in patients who do not meet criteria for deficiency, but the risks associated with are unclear. Hypothesis: Patients initiating therapy would be diagnosed significantly more tendon tears and undergo repairs than matched controls never on therapy. Study Design: Cohort study. Level Evidence: 3. Methods: Male initiated within 30 days a primary care visit did treatment low were identified (n = 112,242). Propensity score matching generated control cohort 448,968) no history based several comorbidities at time said age-matched visit. Rates 1 2 years after compared using multivariable logistic regression. Results: Within years, controls, higher rates rotator cuff tear (odds ratio [OR], 1.35; OR, 1.31), patellar (OR, 2.06; 2.14), any 1.33; 1.31). The quadriceps year 1.59). repair 1.28; 1.23), distal biceps 1.65; 1.54), 2.28; 2.18), 1.27; 1.23). Conclusion: Testosterone is increased risk least first second documented laboratory testing. considering should counseled this injury.

Язык: Английский

---

Hypoandrogenic state inhibits erectile function in rats via miR-200a-3p

The Journal of Sexual Medicine, Год журнала: 2025, Номер unknown

Опубликована: Май 4, 2025

Язык: Английский

---