History of Untreated Psychosis: the Impact on Prognosis of Paranoid Schizophrenia. Case Report
Psikhiatriya,
Год журнала:
2025,
Номер
22(6), С. 72 - 81
Опубликована: Фев. 24, 2025
Background:
psychiatrists
often
face
difficulties
in
selecting
appropriate
psychopharmacological
treatments
when
patients
with
Schizophrenia
spectrum
disorders
have
been
without
adequate
antipsychotic
medication
for
a
long
period.
This
can
lead
to
unforeseen
complications
and
case
managing.
The
relevance
of
this
issue
is
highlighted
by
numerous
clinical
statistical
studies
that
demonstrate
the
high
prevalence
these
among
psychiatric
hospital
patients.
Additionally,
course
illness
vary
depending
on
untreated
period
duration,
which
has
important
scientific
practical
implications
long-term
treatment
outcomes,
therapy
effectiveness,
timing
quality
remissions.
aim:
using
report
as
an
example
evaluate
impact
nontreatment,
we
will
look
at
degree
improvement
psychotic
symptoms
prognosis
paranoid
schizophrenia
after
psychosis.
Patient
Methods:
clinicalpsychopathological
clinical-dynamic
methods
were
used
study
manifestations
patient
syndrome
deficit
symptoms,
within
context
continuous
form
schizophrenia,
against
background
prolonged
Results:
presented
highlights
poor
plan
consisted
combination
traditional
first-generation
antipsychotics
clozapine,
shown
be
highly
effective
safe
treating
paraphrenia
schizophrenia.
Conclusion:
observation
question
emphasized
significance
timely
initiation
onset
first
episode.
Long
psychosis
negatively
effectiveness
overall
outcome
illness.
Язык: Английский
Epidemiology of bipolar disorder ‘with’ vs ‘without’ psychotic features: Distinct subgroups or subjective dichotomy along a continuously distributed, intrinsic symptom domain?
Schizophrenia Research,
Год журнала:
2024,
Номер
267, С. 14 - 15
Опубликована: Март 19, 2024
Язык: Английский
Defining the road to recovery: Cognitive reserve and resilience in severe mental illness
European Neuropsychopharmacology,
Год журнала:
2024,
Номер
88, С. 3 - 4
Опубликована: Авг. 7, 2024
Язык: Английский
What is the duration of untreated psychosis worldwide?
Psychological Medicine,
Год журнала:
2024,
Номер
54(13), С. 3755 - 3757
Опубликована: Сен. 26, 2024
Язык: Английский
Protective Factors Predict Resilient Outcomes in Clinical High-Risk Youth with the Highest Individualized Psychosis Risk Scores
Schizophrenia Bulletin,
Год журнала:
2024,
Номер
unknown
Опубликована: Ноя. 2, 2024
Studying
individuals
at
Clinical
High
Risk
(CHR)
for
psychosis
provides
an
opportunity
to
examine
protective
factors
that
predict
resilient
outcomes.
Here,
we
present
a
model
the
study
of
in
CHR
participants
very
highest
risk
psychotic
conversion
based
on
Psychosis
Calculator.
Язык: Английский
Psychotic Illness as a Disorder of Subtle, Whole-body Maldevelopment: Challenges and Opportunities for Drug Discovery
Royal Society of Chemistry eBooks,
Год журнала:
2024,
Номер
unknown, С. 19 - 30
Опубликована: Дек. 6, 2024
Research
seeking
to
identify
the
pathobiology
of
and
improved
treatments
for
schizophrenia
related
psychotic
illness
has
focussed,
continues
focus,
on
brain
dysfunction
its
origins.
Yet
there
is
a
wide
still
increasing
array
biological
abnormalities
in
that
appear
reflect
non-cerebral
involvement.
This
review
considers
evidence
whole-body
concept
pathobiology,
focussing
particularly
anatomy,
metabolism,
immunity
inflammation,
cancer,
gut
microbiome
microRNAs.
These
findings
reinforce
pleiotropic
effect
genetic
risk
across
whole
body
indicate
both
challenges
opportunities
drug
discovery.
Язык: Английский