Polymer Bulletin, Год журнала: 2025, Номер unknown
Опубликована: Июнь 3, 2025
Язык: Английский
Materials Today Chemistry, Год журнала: 2023, Номер 34, С. 101818 - 101818
Опубликована: Ноя. 18, 2023
Язык: Английский
Процитировано
64
ACS Applied Bio Materials, Год журнала: 2024, Номер 7(8), С. 5082 - 5106
Опубликована: Июль 15, 2024
In view of their exceptional approach, excellent inherent biocompatibility and biodegradability properties, interaction with the local extracellular matrix, protein-based polymers have received attention in bone tissue engineering, which is a multidisciplinary field that repairs regenerates fractured bones. Bone multihierarchical complex structure, it performs several essential biofunctions, including maintaining mineral balance structural support protecting soft organs. Protein-based gained interest developing ideal scaffolds as emerging biomaterials for healing regeneration, challenging to design substitutes perfect biomaterials. Several polymers, collagen, keratin, gelatin, serum albumin, etc., are potential materials due cytocompatibility, controlled biodegradability, high biofunctionalization, tunable mechanical characteristics. While numerous studies indicated encouraging possibilities proteins BTE, there still major challenges concerning stability physiological conditions, continuous release growth factors bioactive molecules. Robust derived from can be used replace broken or diseased biocompatible substitute; proteins, being biopolymers, provide engineering. Herein, recent developments protein cutting-edge engineering addressed this review within 3–5 years, focus on significant future perspectives. The first section discusses fundamentals anatomy scaffolds, second describes fabrication techniques scaffolds. third highlights importance applications BTE. Hence, development state-of-the-art has been discussed, highlighting
Язык: Английский
Процитировано
26
Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials, Год журнала: 2024, Номер 151, С. 106391 - 106391
Опубликована: Янв. 9, 2024
Язык: Английский
Процитировано
22
Journal of Orthopaedic Translation, Год журнала: 2025, Номер 50, С. 257 - 273
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
3
International Journal of Biological Macromolecules, Год журнала: 2023, Номер 254, С. 127660 - 127660
Опубликована: Окт. 29, 2023
Язык: Английский
Процитировано
35
Journal of Drug Delivery Science and Technology, Год журнала: 2024, Номер 96, С. 105689 - 105689
Опубликована: Апрель 21, 2024
In the last few years, wound healing and development of "ideal" biomaterials that provide quick recovery minimize scarring have represented one most important priorities researchers. this direction, silk fibroin (SF) scaffolds gained substantial awareness, as a promising polymer owing to their increased biocompatibility, outstanding mechanical properties, biodegradability, especially tensile strength. Furthermore, SF is acknowledged accelerate process by encouraging cell growth proliferation, also migration different types cells are included in stages process. Therefore, metal oxide nanoparticles (NPs), such iron (FeO), copper (CuO), zinc (ZnO), or magnesium (MgO) NPs, been extensively researched for antimicrobial properties ability enhance tissue regeneration addition SF. When introduced within scaffolds, these NPs impart enhanced including improved scaffold stability durability. Moreover, presence could increase biocompatibility facilitating adhesion, migration, ultimately promoting processes. The incorporation other natural polymers into has thus emerged favorable method therapeutic potential developed biomaterial. This review aims an overview advancements containing applications.
Язык: Английский
Процитировано
17
Biomimetics, Год журнала: 2024, Номер 9(7), С. 390 - 390
Опубликована: Июнь 26, 2024
This review explores the extensive applications of plants in areas biomimetics and bioinspiration, highlighting their role developing sustainable solutions across various fields such as medicine, materials science, environmental technology. Plants not only serve essential ecological functions but also provide a rich source inspiration for innovations green nanotechnology, biomedicine, architecture. In past decade, focus has shifted towards utilizing plant-based vegetal waste creating eco-friendly cost-effective with remarkable properties. These are employed making advancements drug delivery, remediation, production renewable energy. Specifically, discusses use (nano)bionic capable detecting explosives contaminants, underscoring potential improving quality life even lifesaving applications. The work refers to architectural inspirations drawn from plant world develop novel design concepts that both functional aesthetic. It elaborates on how engineered have been transformed into value-added through innovative applications, especially roles wastewater treatment electronic components. Moreover, integration synthesis biocompatible medical tissue engineering scaffolds artificial muscles demonstrates versatility capacity replace more traditional synthetic materials, aligning global sustainability goals. paper provides comprehensive overview current uses living technological advancements, advocating deeper exploration address pressing challenges.
Язык: Английский
Процитировано
17
Biofabrication, Год журнала: 2024, Номер 17(1), С. 012005 - 012005
Опубликована: Ноя. 8, 2024
Abstract Artificial bone graft stands out for avoiding limited source of autograft as well susceptibility to infection allograft, which makes it a current research hotspot in the field defect repair. However, traditional design and manufacturing method cannot fabricate scaffold that mimics complicated bone-like shape with interconnected porous structure multiple properties akin human natural bone. Additive manufacturing, can achieve implant’s tailored external contour controllable fabrication internal microporous structure, is able form almost any designed via layer-by-layer process. As additive promising building artificial scaffold, only combining excellent structural appropriate process produce ideal biological mechanical properties. In this article, we sum up analyze state art methods realize shape/properties collaborative intelligent manufacturing. Scaffold be mainly classified into based on unit cells whole while basic 3D bioprinting are recommended suitable fabrication. The challenges future perspectives manufactured also discussed.
Язык: Английский
Процитировано
11
Processes, Год журнала: 2024, Номер 12(2), С. 358 - 358
Опубликована: Фев. 8, 2024
Food waste, particularly animal-derived presents a significant challenge globally, prompting the need for sustainable management strategies. In 2022, amount of food waste per capita reached 131 kg/capita in EU (European Union), which is why search environmentally friendly ways to manage through thermochemical conversion processes has gained momentum recent years. Animal-derived good source organic matter (proteins, lipids, and polysaccharides) mineral compounds (calcium phosphate, mostly hydroxyapatite). This composition makes valuable extraction chemical compounds, such as hydroxyapatite (HAp), constitutes up 70 wt% animal bones; keratin; collagen; hyaluronic acid (HA), produce pharmaceutical, medical, or industrial by-products. The chicken bones pyrolysis gasification creates new opportunity valorize this type by reintroducing by-products into economy thus achieving objectives. results study showcase multiple applications bone products (as adsorbents aqueous mediums, catalysts, fertilizers, biomedical applications) necessity better exploration process waste. Therefore, explores properties discusses influence conditions on product yields, catalytic enhancement these processes.
Язык: Английский
Процитировано
9
Tissue Engineering Part B Reviews, Год журнала: 2025, Номер unknown
Опубликована: Янв. 6, 2025
Synthetic bone transplantation has emerged in recent years as a highly promising strategy to address the major clinical challenge of tissue defects. In this field, bioactive glasses (BGs) have been widely recognized viable alternative traditional substitutes due their unique advantages, including favorable biocompatibility, pronounced bioactivity, excellent biodegradability, and superior osseointegration properties. This article begins with comprehensive overview development success BGs engineering, then focuses on composite reinforcement systems biodegradable metals, calcium-phosphorus (Ca-P)-based bioceramics, medical polymers, respectively. Moreover, outlines some frequently used manufacturing methods for three-dimensional BG-based bioscaffolds highlights remarkable achievements these scaffolds field defect repair years. Lastly, based many potential challenges encountered preparation application BGs, brief outlook future directions is presented. review may help provide new ideas researchers develop ideal reconstruction functional recovery.
Язык: Английский
Процитировано
1