Advancing mechanical and biological characteristics of polymer-ceramic nanocomposite scaffolds for sport injuries and bone tissue engineering: A comprehensive investigation applying finite element analysis and artificial neural network

Ceramics International, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Язык: Английский

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Piezoelectric Biomaterials for Use in Bone Tissue Engineering—A Narrative Review

Journal of Biomedical Materials Research Part B Applied Biomaterials, Год журнала: 2025, Номер 113(4)

Опубликована: Март 17, 2025

ABSTRACT To examine natural bone's bioelectrical traits, notably its piezoelectricity, and to look into how these characteristics influence bone growth repair. In the context of exploring potential piezoelectric biomaterials, such as biopolymers bio‐ceramics, towards orthopedic regeneration applications, research seeks evaluate significance piezoelectricity‐driven osteogenesis. The paper reviews recent on electrical dielectric properties, surface polarization/electrical stimulation effects interacting with cell activity effectiveness biomaterials support tissues' regenerative process. study includes a number materials, collagen, polyvinylidene fluoride (PVDF) barium titanate. applications organic polymers, polymers are particularly highlighted. Piezoelectric being shown in studies enhance cellular metabolism vitro well promote tissues vivo, especially when paired electric field or interface polarization. bio‐ceramics like magnesium silicate titanate, collagen PVDF, have possibilities for applications. However, there several challenges regarding manufacturing specific compositions having desired properties. This review highlighted special emphasis bioceramics. Therefore, types materials huge because they can mimic properties allow better advances tissue engineering medicine. date, little is known about their mechanism action, modifications needed improve efficacy clinical uptake.

Язык: Английский

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Current Research in Drug-Free Cancer Therapies

Bioengineering, Год журнала: 2025, Номер 12(4), С. 341 - 341

Опубликована: Март 26, 2025

Cancer treatment has historically depended on conventional methods like chemotherapy, radiation, and surgery; however, these strategies frequently present considerable limitations, including toxicity, resistance, negative impacts healthy tissues. In addressing challenges, drug-free cancer therapies have developed as viable alternatives, utilizing advanced physical biological to specifically target tumor cells while reducing damage normal This review examines several strategies, such high-intensity focused energy beams, nanosecond pulsed electric fields, photothermal therapy well the use of inorganic nanoparticles promote selective apoptosis. We also investigate significance targeting microenvironment, precision medicine, immunotherapy in progression personalized therapies. Although approaches demonstrate significant promise, challenges scalability, safety, regulatory obstacles must be resolved for clinical application. paper presents an overview current research therapies, emphasizing recent advancements, underlying scientific principles, steps required implementation.

Язык: Английский

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Macroporous Ag-HAp Materials for Antibacterial Photothermal Membranes in Solar Steam Generation Systems

Research Square (Research Square), Год журнала: 2025, Номер unknown

Опубликована: Март 27, 2025

The increasing global demand for clean water has driven significant research into solar steam generation and purification technologies. Hydroxyapatite (HAp), a biocompatible chemically stable material, demonstrated promise treatment due to its excellent adsorption properties. However, microbial contamination poses challenge in application generation. Herein, novel macroporous silver-doped hydroxyapatite (Ag-HAp) nanocomposite was used the first time fabricating photothermal membranes. incorporation of Ag Ag-HAp significantly alters structure, introducing voids, which are transportation release results show that membrane achieved an evaporation rate 1.202 kgm^{− 2}h^{− 1} under one-sun illumination, 1.33-fold increase compared pure HAp Additionally, antibacterial evaluations using disc diffusion method revealed activity against Escherichia coli Staphylococcus aureus, with inhibition zones concentration. These findings highlight potential nanocomposites as efficient durable solution harvesting purification.

Язык: Английский

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Structural Transformations in Mechanochemically-Synthesized Strontium-Doped Hydroxyapatite

Ceramics International, Год журнала: 2025, Номер unknown

Опубликована: Апрель 1, 2025

Язык: Английский

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Biocompatibility And Periodontal Regenerative Potential Of Hydroxyapatite Nanoparticles From Portunus Sanguinolentus Shells: A Crystallographic, Morphological, And Molecular Gene Expression Analysis"

Journal of Dentistry, Год журнала: 2025, Номер unknown, С. 105762 - 105762

Опубликована: Апрель 1, 2025

Язык: Английский

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Investigating biomimetic coatings on Ti-6Al-4V substrates

Deleted Journal, Год журнала: 2025, Номер 7, С. 100082 - 100082

Опубликована: Апрель 28, 2025

Язык: Английский

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Characterization of Hydroxyapatite Extracted from Crab Shell Using the Hydrothermal Method with Varying Holding Times

JOURNAL OF RENEWABLE MATERIALS, Год журнала: 2024, Номер 12(6), С. 1145 - 1163

Опубликована: Янв. 1, 2024

Язык: Английский

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Dual Porous Architecture of Poly(ε-Caprolactone) Scaffold Loaded with Nanostructured Carbonated Hydroxyapatite and Cellulose Nanofibril Enhances In Vitro Biocompatibility

Materials Chemistry and Physics, Год журнала: 2025, Номер unknown, С. 130798 - 130798

Опубликована: Март 1, 2025

Язык: Английский

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Novel enhancing materials for biosensor design: The case studies of erbium-, gadolinium- and strontium-doped Ca10(PO4)6(OH)2 hydroxyapatite

Progress in Crystal Growth and Characterization of Materials, Год журнала: 2024, Номер 70(4), С. 100637 - 100637

Опубликована: Сен. 7, 2024

Язык: Английский

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