Gradually-frozen aligned bacterial nanocellulose membranes loaded with gallic acid exhibit enhanced mechanical and dual antithrombotic-antimicrobial properties DOI Creative Commons

Emma D. Stephens,

Fereshteh Oustadi,

Hunter Marcelo

и другие.

Biomaterials Science, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Bacterial nanocellulose (BNC) is a versatile natural polymer with unique morphological properties. However, its susceptibility to biofouling limits utility in healthcare. To address this challenge, study explores the incorporation of gallic acid, phenolic acid potent antimicrobial and antithrombotic properties, into BNC membranes. Additionally, novel drying method termed gradual freezing introduced, resulting directionally-aligned membrane enhanced mechanical integrity high porosity. Using glycerol as solvent plasticizer, was loaded air-dried (AD-BNC), freeze-dried (FD-BNC), gradually-frozen (GF-BNC) Successful drug-loading FD-BNC GF-BNC significantly increased elasticity films, however testing indicated that acid/glycerol counterpart (GF-GG-BNC) achieved overall optimal strength elasticity. These samples were selected for further antifouling testing. Antibacterial assays demonstrated practical efficacy GF-GG-BNC inhibiting proliferation biofilm formation E. coli S. aureus, while favorable behaviour prevented clot red blood cell adhesion on material's surface when compared findings highlight potential multifunctional biomaterial prevention biomedical applications.

Язык: Английский

Açaí powder-enriched biodegradable starch films: Characterization, release in food simulants and protective effect in photodegradation system DOI

Franciele Silva Maciel,

Renato Queiroz Assis, Alessandro de Oliveira Rios

и другие.

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 142420 - 142420

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0
Gradually-frozen aligned bacterial nanocellulose membranes loaded with gallic acid exhibit enhanced mechanical and dual antithrombotic-antimicrobial properties DOI Creative Commons

Emma D. Stephens,

Fereshteh Oustadi,

Hunter Marcelo

и другие.

Biomaterials Science, Год журнала: 2025, Номер unknown

Опубликована: Янв. 1, 2025

Bacterial nanocellulose (BNC) is a versatile natural polymer with unique morphological properties. However, its susceptibility to biofouling limits utility in healthcare. To address this challenge, study explores the incorporation of gallic acid, phenolic acid potent antimicrobial and antithrombotic properties, into BNC membranes. Additionally, novel drying method termed gradual freezing introduced, resulting directionally-aligned membrane enhanced mechanical integrity high porosity. Using glycerol as solvent plasticizer, was loaded air-dried (AD-BNC), freeze-dried (FD-BNC), gradually-frozen (GF-BNC) Successful drug-loading FD-BNC GF-BNC significantly increased elasticity films, however testing indicated that acid/glycerol counterpart (GF-GG-BNC) achieved overall optimal strength elasticity. These samples were selected for further antifouling testing. Antibacterial assays demonstrated practical efficacy GF-GG-BNC inhibiting proliferation biofilm formation E. coli S. aureus, while favorable behaviour prevented clot red blood cell adhesion on material's surface when compared findings highlight potential multifunctional biomaterial prevention biomedical applications.

Язык: Английский

Процитировано

0