Plant Foods for Human Nutrition, Год журнала: 2023, Номер 78(2), С. 320 - 328
Опубликована: Март 22, 2023
Язык: Английский
Biomedicines, Год журнала: 2023, Номер 11(1), С. 136 - 136
Опубликована: Янв. 5, 2023
Sarcopenia is a multifactorial condition related to the loss of muscle mass and strength due aging, eating habits, physical inactivity, or even caused by another disease. Affected individuals have higher risk falls may be associated with heart disease, respiratory diseases, cognitive impairment, consequently an increased hospitalization, in addition causing economic impact high cost care during stay hospitals. The standardization appropriate treatment for patients sarcopenia that could help reduce pathology-related morbidity necessary. For these reasons, this study aimed perform systematic review role nutrition drugs ameliorate health quality life sarcopenic PRISMA guidelines were followed. Lifestyle interventions shown profound on but using supplements different can also skeletal maintenance. Creatine, leucine, branched-chain amino acids, omega 3, vitamin D show benefits. Although controversial results, medications such as Metformin, GLP-1, losartan, statin, growth hormone, dipeptidyl peptidase 4 inhibitors been considered alter sarcopenic's metabolic parameters, protect against cardiovascular diseases outcomes, while protecting muscles.
Язык: Английский
Процитировано
45
Antioxidants, Год журнала: 2024, Номер 13(4), С. 393 - 393
Опубликована: Март 25, 2024
The aging of the global population has increased prevalence neurodegenerative conditions. Bacopa monnieri (BM), an herb with active compounds, such as bacosides A and B, betulinic acid, loliolide, asiatic quercetin, demonstrates potential for brain health. Limited research been conducted on therapeutic applications BM in This systematic review aims to project BM’s beneficial role disorders. anti-apoptotic antioxidant actions can repair damaged neurons, stimulate kinase activity, restore synaptic function, improve nerve transmission, increase neuroprotection. included twenty-two clinical trials demonstrated that reduce Nuclear Factor-κB phosphorylation, emotional cognitive functions, anhedonia, hyperactivity, sleep routine, depression, attention deficit, learning problems, memory retention, impulsivity, psychiatric problems. Moreover, levels pro-inflammatory biomarkers oxidative stress. Here, we highlight provides notable benefits serve a complementary approach care patients conditions associated adds growing interest natural products their by improving our understanding mechanisms underlying function neurodegeneration informing development new strategies diseases.
Язык: Английский
Процитировано
37
Biomedicines, Год журнала: 2024, Номер 12(3), С. 574 - 574
Опубликована: Март 5, 2024
Neurodegeneration poses a significant challenge for the fields of neuroscience and medicine, as it is underlying cause development advancement numerous neurodegenerative psychiatric disorders [...]
Язык: Английский
Процитировано
25
Biomedicines, Год журнала: 2024, Номер 12(3), С. 613 - 613
Опубликована: Март 8, 2024
Neuroscience, neurology, and psychiatry are rapidly evolving fields that aim to understand the complex mechanisms underlying brain function dysfunction, as well develop effective interventions for various neurological psychiatric disorders [...]
Язык: Английский
Процитировано
19
Biomedicines, Год журнала: 2024, Номер 12(5), С. 1083 - 1083
Опубликована: Май 13, 2024
Welcome to
Язык: Английский
Процитировано
17
Опубликована: Март 5, 2024
Delve into the dynamic realms of neuroscience, neurology, and psychiatry with this groundbreaking editorial, unveiling intricate mechanisms brain function dysfunction. Explore latest advancements in molecular biology, genetics, epigenetics, pharmacology, neuroimaging that are revolutionizing our understanding neurological psychiatric disorders. Uncover challenges gaps translating cutting-edge research practical clinical applications, aiming to enhance lives patients their families. Discover pivotal role neuroplasticity reshaping brain's adaptability throughout life, alongside promising potential non-invasive stimulation techniques like transcranial magnetic direct current stimulation. Embark on a journey innovation collaboration as researchers clinicians strive bridge gap between bench bedside, offering hope for improved diagnosis, prevention, treatment complex conditions. Join us exploration transformative ideas novel interventions hold key brighter future individuals society.
Язык: Английский
Процитировано
16
Frontiers in Pharmacology, Год журнала: 2022, Номер 13
Опубликована: Июнь 2, 2022
Panax ginseng and notoginseng, two well-known herbs with enormous medical value in Asian countries, have a long usage history China for the therapy of some diseases, such as stroke. Ginsenoside Rb1 is one most important active ingredients notoginseng. In last decades, more attention has focused on ginsenoside an antioxidative, anti-apoptotic anti-inflammatory agent that can protect nervous system. review, we summarize neuroprotective roles its potential mechanisms central system diseases (CNSDs), including neurodegenerative cerebral ischemia injury, depression spinal cord injury. conclusion, neuroprotection due to inhibition oxidative stress, apoptosis, neuroinflammation autophagy CNSDs may be promising candidate clinical future.
Язык: Английский
Процитировано
38
Journal of Neural Transmission, Год журнала: 2024, Номер 131(12), С. 1367 - 1387
Опубликована: Авг. 7, 2024
Millions of individuals around the world are afflicted with Parkinson's disease (PD), a prevalent and incapacitating neurodegenerative disorder. Dr. Reichmann, distinguished professor neurologist, has made substantial advancements in domain PD research, encompassing both fundamental scientific investigations practical applications. His research illuminated etiology treatment PD, as well function energy metabolism premotor symptoms. As precursor to number neurotransmitters neuromodulators that implicated pathophysiology he also investigated application tryptophan (Trp) derivatives disease. principal findings insights summarized synthesized this narrative review article, which emphasizes challenges implications for future research. This aims identify analyze key contributions Reichmann field ultimate goal informing directions domain. By examining Reichmann's work, study seeks provide comprehensive understanding his major how they can be applied advance diagnosis PD. paper explores potential intersection emerging avenues, such investigation Trp its metabolites, particularly kynurenines, could lead new therapeutic strategies managing disorders like
Язык: Английский
Процитировано
9
Plant Science, Год журнала: 2024, Номер 341, С. 112022 - 112022
Опубликована: Фев. 3, 2024
Язык: Английский
Процитировано
8
Nutrients, Год журнала: 2024, Номер 16(16), С. 2721 - 2721
Опубликована: Авг. 15, 2024
Aging-related disorders pose significant challenges due to their complex interplay of physiological and metabolic factors, including inflammation, oxidative stress, mitochondrial dysfunction. Curcumin, a natural compound with potent antioxidant anti-inflammatory properties, has emerged as promising candidate for mitigating these age-related processes. However, gaps in understanding the precise mechanisms curcumin’s effects optimal dosages different conditions necessitate further investigation. This systematic review synthesizes current evidence on potential addressing disorders, emphasizing its impact cognitive function, neurodegeneration, muscle health older adults. By evaluating safety, efficacy, action curcumin supplementation, this aims provide insights into therapeutic promoting healthy aging. A search across three databases using specific keywords yielded 2256 documents, leading selection 15 clinical trials synthesis. Here, we highlight multifaceted agent combating disorders. The findings suggest that could offer effective approach enhancing quality life aging individuals. Further research well-designed are essential validate optimize use personalized medicine approaches conditions.
Язык: Английский
Процитировано
8