World Journal of Psychiatry,
Год журнала:
2025,
Номер
15(5)
Опубликована: Апрель 30, 2025
BACKGROUND
The
assessment
of
nutritional
status
in
non-dialysis
elderly
patients
with
chronic
kidney
disease
(CKD)
and
comorbid
depression
is
clinically
important.
Determining
key
determinants
this
population
significantly
improves
management
strategies
assists
these
overcome
the
disease.
AIM
To
investigate
factors
influencing
CKD
depression.
METHODS
This
study
retrospectively
collected
clinical
data
182
admitted
at
Tangdu
Hospital,
Air
Force
Medical
University,
from
January
2022
to
June
2023.
participants
were
categorized
based
on
presence
malnutrition
into
nutritionally
normal
group
(n
=
97)
85).
two
groups
subjected
unifactorial
multifactorial
regression
analyze
among
participants.
Data
included
sex,
age,
body
mass
index
(BMI),
percentage
fat,
basal
metabolic
rate
(BMR),
blood
urea
nitrogen
(BUN),
creatinine
(Cr),
albumin
(Alb),
hemoglobin
(Hb),
pre-albumin
(PA),
patient-generated
subjective
global
assessment,
Patient
Health
Questionnaire-9
(PHQ-9)
score
identify
depressive
symptoms.
After
admitting
hospital,
5
mL
peripheral
serum
was
withdrawn,
centrifuge
operated
3500
rpm/minute
a
centrifugal
radius
10
cm
for
minutes,
collected,
Alb,
Hb,
PA,
BUN,
Cr
levels
detected
using
fully
automatic
biochemical
analyzer.
results
assessed
Statistical
Package
Social
Sciences
version
21.0
conducting
technical
analyses.
Metric
are
presented
as
mean
±
standard
error
replaced
t
-test.
Count
expressed
case
counts
percentages
χ
2
test.
Effective
modeled
logistic
return
modeling.
RESULTS
BMI,
BMR,
lower
than
group.
Furthermore,
BUN
levels,
PHQ-9
scores,
anxiety
symptoms
greater
nutrition
group,
statistically
significant
differences
(P
<
0.05).
Multiple
factorial
interpretations
revealed
PA
CONCLUSION
Serum
all
depression;
hence,
interventions
can
be
targeted
above
characteristics.
Molecular Nutrition & Food Research,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 21, 2025
ABSTRACT
This
study
explores
the
effects
of
a
nutraceutical
blend
with
prebiotics,
β‐glucans,
essential
minerals,
and
silymarin
on
gut
microbiota,
inflammation,
sleep
quality
in
obesity
through
microbiota
reshaping
metabolic
improvements
over
90
days.
A
double‐blind,
randomized
trial
was
conducted
77
participants
divided
into
two
groups
receiving
either
standard
(NSupple)
or
silymarin‐enriched
(NSupple_
Silybum
).
Fecal
plasma
samples
were
collected
at
baseline
post‐supplementation
for
metabolic,
inflammatory
marker
analysis.
The
results
showed
reduction
body
weight,
waist‐to‐height
ratio,
total
cholesterol,
fractions
NSupple_
group.
There
dysbiosis
recovery
shown
by
increase
beneficial
bacteria,
such
as
Lentisphaerae
phylum,
Lactobacillus
Faecalibacterium
genera,
prausnitzii
NSupple
group,
concurrent
Adlercreutzia
Sutterella
Both
demonstrated
improved
profiles
reduced
TNF‐α/IL‐10
cortisol
levels,
Firmicutes/Bacteroides
ratio.
Additionally,
associated
reductions
pro‐inflammatory
cytokines
composition.
reshaped
enhanced
anti‐inflammatory
species,
parameters,
highlighting
its
potential
nutritional
strategy
managing
reducing
inflammation.
Frontiers in Nutrition,
Год журнала:
2025,
Номер
12
Опубликована: Март 10, 2025
Introduction
Depression
is
a
psychological
condition
characterized
by
persistent
low
mood.
This
study
investigates
the
relationship
between
depressive
symptoms
and
food
preferences
in
undergraduate
students.
Methods
A
cross-sectional
design
was
employed
among
502
students
at
Zanjan
University
of
Medical
Sciences.
Data
collection
included
validated
questionnaires
on
preferences,
depression
levels
(Beck
Inventory),
physical
activity
(IPAQ),
along
with
anthropometric
measurements.
Food
were
analyzed
for
six
groups:
grains,
fruits,
vegetables,
dairy,
meat/fish,
snacks.
severity
categorized
into
based
BDI
scores:
normal
(1–9),
mild
(10–16),
borderline
(17–20),
moderate
(21–30),
severe
(31–40),
very
(41–63).
risk
defined
as
odds
belonging
to
higher
Beck
Inventory
(BDI)
category.
Results
Participants
had
lower
vegetables
but
Adjusted
analyses
revealed
that
fruits
(OR:
0.79;
95%
CI:
0.68–0.98)
0.81;
0.71–0.94)
significantly
associated
reduced
risk,
while
snack
increased
1.28;
1.03–1.68).
However,
association
grain
not
statistically
significant
after
adjustment
0.82;
0.74–1.03).
Conclusion
These
findings
highlight
bidirectional
link
diet
mental
health,
underscoring
importance
dietary
interventions
health
strategies.
World Journal of Psychiatry,
Год журнала:
2025,
Номер
15(5)
Опубликована: Апрель 30, 2025
BACKGROUND
The
assessment
of
nutritional
status
in
non-dialysis
elderly
patients
with
chronic
kidney
disease
(CKD)
and
comorbid
depression
is
clinically
important.
Determining
key
determinants
this
population
significantly
improves
management
strategies
assists
these
overcome
the
disease.
AIM
To
investigate
factors
influencing
CKD
depression.
METHODS
This
study
retrospectively
collected
clinical
data
182
admitted
at
Tangdu
Hospital,
Air
Force
Medical
University,
from
January
2022
to
June
2023.
participants
were
categorized
based
on
presence
malnutrition
into
nutritionally
normal
group
(n
=
97)
85).
two
groups
subjected
unifactorial
multifactorial
regression
analyze
among
participants.
Data
included
sex,
age,
body
mass
index
(BMI),
percentage
fat,
basal
metabolic
rate
(BMR),
blood
urea
nitrogen
(BUN),
creatinine
(Cr),
albumin
(Alb),
hemoglobin
(Hb),
pre-albumin
(PA),
patient-generated
subjective
global
assessment,
Patient
Health
Questionnaire-9
(PHQ-9)
score
identify
depressive
symptoms.
After
admitting
hospital,
5
mL
peripheral
serum
was
withdrawn,
centrifuge
operated
3500
rpm/minute
a
centrifugal
radius
10
cm
for
minutes,
collected,
Alb,
Hb,
PA,
BUN,
Cr
levels
detected
using
fully
automatic
biochemical
analyzer.
results
assessed
Statistical
Package
Social
Sciences
version
21.0
conducting
technical
analyses.
Metric
are
presented
as
mean
±
standard
error
replaced
t
-test.
Count
expressed
case
counts
percentages
χ
2
test.
Effective
modeled
logistic
return
modeling.
RESULTS
BMI,
BMR,
lower
than
group.
Furthermore,
BUN
levels,
PHQ-9
scores,
anxiety
symptoms
greater
nutrition
group,
statistically
significant
differences
(P
<
0.05).
Multiple
factorial
interpretations
revealed
PA
CONCLUSION
Serum
all
depression;
hence,
interventions
can
be
targeted
above
characteristics.