A review on health benefits of phenolics derived from dietary spices

Current Research in Food Science, Год журнала: 2022, Номер 5, С. 1508 - 1523

Опубликована: Янв. 1, 2022

Spices are an affluentpool of polyphenolcompounds that possessgigantic medicinal peculiarities such as remedying microbial infections, oxidative stress, inflammation, diabetes, cancers, neurodegenerative disorders, cardiac etc. On account, thepresent review illustrates the therapeutic potential, mechanism action, and different procedures for conscious extraction polyphenols. The various ethnopharmacological properties; reasons their diverse pharmacological actions action spices-derived phenolics have also been discussed. findings this may be utilized by food pharmaceutical industries developing suitable alternatives to synthetic antioxidants can developed into effective supplements. Further in-depth scientific studies needed find out actual exact relevance natural health boosters. Moreover, clinical toxicological required harnessing full potential polyphenols derived from dietary spices.

Язык: Английский

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The multifaceted potential of fenugreek seeds: From health benefits to food and nanotechnology applications

Food Science & Nutrition, Год журнала: 2024, Номер 12(4), С. 2294 - 2310

Опубликована: Янв. 10, 2024

Abstract The present lifestyle, dietary patterns, psychological pressure, environmental factors, and the widespread exploitation of processed substances in food production farming have collectively contributed to a substantial expediting development various health problems. Globally, researchers been seeking natural pharmaceutical with potential be employed treating lifestyle‐related diseases or delaying their onset. Fenugreek seeds gained significant attention fields, including health, nutrition, cutting‐edge nanotechnology applications, due versatile qualities. current investigation offers comprehensive discussion nutritional composition therapeutic fenugreek seeds, an emphasis on plentiful reservoir bioactive compounds. This seed demonstrates promising medicinal addressing wide range issues. Significantly, these findings indicate noteworthy properties, such as antidiabetic, antioxidant, anti‐obesity, hypocholesterolemic, anticancer, cardioprotective effects. Moreover, components are important multitude foods, which is reason why they used extensively area research. In addition value, exploration reveals domain, utilizing distinctive characteristics for many purposes, nanoparticle synthesis oil edible films nanoemulsions. review article focuses analysis examining wide‐ranging applications fields food, nanotechnology.

Язык: Английский

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Current perspectives on fenugreek bioactive compounds and their potential impact on human health: A review of recent insights into functional foods and other high value applications

Journal of Food Science, Год журнала: 2024, Номер 89(4), С. 1835 - 1864

Опубликована: Фев. 26, 2024

Despite long-standing uses in several food and medicine traditions, the full potential of leguminous crop fenugreek (Trigonella foenum-graecum L.) remains to be realized modern diet. Not only its seeds, which are highly prized for their culinary medicinal properties, but also leaves stems abound phytochemicals with high nutritional health promoting attributes. Fenugreek dual food-medicine applications reported metabolic activities include hypoglycemic, antihyperlipidemic, antioxidative, anti-inflammatory, antiatherogenic, antihypertensive, anticarcinogenic, immunomodulatory, antinociceptive effects, organ-protective effects at cardiovascular, digestive, hepatic, endocrine, central nervous system levels. Effectiveness alleviating certain inflammatory skin conditions dysfunctions reproductive was suggested. As a ingredient, can enhance sensory, nutritional, nutraceutical qualities wide variety foods. Its nutritive density assist design dietary items that meet demand novelty, variety, healthier seeds provide essential protective nutrients other bioactive compounds, notably galactomannans, flavonoids, coumarins, saponins, alkaloids, oils, whose benefits, alone or conjunction bioactives, beginning tapped into industries. This review summarizes current state evidence on functional development, focusing non-nutrient components interest from perspective, enhancing value foods beverages. New developments, safety, clinical evidence, presumed mechanisms action, future perspectives discussed. HIGHLIGHTS: have continuum. exert broad-spectrum biological pharmacological activities. They show preventive against common chronic diseases. Current supports multiple action mediated by distinct bioactives. Opportunities fenugreek-based nutraceuticals expanding.

Язык: Английский

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Fenugreek seeds as a natural source of L-arginine-encapsulated lipid nanoparticles against diabetes

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Фев. 27, 2025

Diabetes, affecting over 10.5% of the global population, leads to severe health complications and economic burdens, highlighting urgent need for effective therapeutic approaches. Current treatments are often insufficient, prompting exploration novel agents delivery mechanisms. This study addresses this gap by investigating roles L-arginine (identified as a target drug candidate through network pharmacology) in diabetes management, while also evaluating lipid nanocarriers synthesized from fenugreek seed oil improved delivery. Our docking analyses revealed L-arginine's strong interactions with diabetes-target genes (CYP1A2, CYP2C19, NFKB), multiple hydrogen bonds binding energies ranging − 7.2 8.9 kcal/mol. Encapsulated nanoparticles were characterized using UV-Visible spectroscopy, showing absorbance peaks at 415 nm simple 521 L-arginine-loaded nanoparticles. Scanning electron microscopy confirmed an average nanoparticle size 100.2 nm, zeta potential analysis indicated neutral surface charge (− 9.37 mV). Antioxidative activity showed 84.44% inhibition IC50 value 40.5 µg/mL The inhibited albumin denaturation 81.10% alpha-amylase 89.30%, surpassing metformin (78.43% 1000 µg/mL). Hemolysis percentage was minimal 10.54%. These findings demonstrate anti-diabetic agent highlight efficacy innovative systems, providing foundation advancing interventions against diabetes.

Язык: Английский

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Variability in proximate composition, phytochemical traits and antioxidant properties of Iranian agro-ecotypic populations of fenugreek (Trigonella foenum-graecum L.)

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Янв. 2, 2024

Abstract Fenugreek ( Trigonella foenum-graecum L.) is a multi-use annual forage legume crop that widely used in food products such as syrup, bitter run, curries, stew, and flavoring. In the present study, morphological traits, proximate composition (moisture, crude fibre, protein, fat, carbohydrate, energy value), total phenol flavonoid contents, antioxidant properties of 31 Iranian agro-ecotypic populations plant was investigated. Among leaf seed samples studied, seeds exhibited high ash (3.94 ± 0.12%), fat (7.94 0.78%), fibre (10.3 0.25%), protein (35.41 1.86%), carbohydrate (50.5 1.90%) content. general, more value (kcal/100 g) also obtained from (318.88 1.78–350.44 1.27) than (45.50 1.32–89.28 0.85). Antioxidant activity power were ranged 67.95 0.05‒157.52 0.20 μg/ml 45.17 0.01‒361.92 0.78 μmol Fe +2 per g dry weigh, respectively. Positive linear correlations between phenolic compounds observed. A significant correlation (dependent variable) some features (independent Considerable variability studied traits among can be interestingly further production systems.

Язык: Английский

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Pharmacological and Therapeutic Properties of Fenugreek (Trigonella foenum-graecum) Seed: A Review

The Journal of Phytopharmacology, Год журнала: 2024, Номер 13(2), С. 97 - 104

Опубликована: Апрель 30, 2024

Fenugreek, scientifically known as Trigonella foenum-graecum, is a versatile annual leguminous plant belonging to the Fabaceae family. It cultivated worldwide and serves numerous purposes spice, herb, food, medicine. Fenugreek resilient can thrive in various environments, including those with drought conditions. The abundant active constituents such saponins, flavonoids, alkaloids, steroids. Additionally, it an excellent source of dietary fiber, protein, linoleic acid, linolenic vitamins A, B1, B2, C. has rich history traditional medicine, particularly Ayurveda, Unani, Tibetan Studies have shown that possesses antimicrobial, antioxidant, antidiabetic, antihyperlipidemic, antiobesity, anticancer, anti-inflammatory, carminative, aphrodisiac, emollient properties. Moreover, its seed polysaccharide content made useful food industry stabilizer, adhesive, emulsifying agent. This article provides overview history, cultivation, nutritional components, nutraceutical role, safety, toxicological properties fenugreek. Its main aim summarize benefits this "golden seed" associated aspects.

Язык: Английский

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Deciphering agronomic traits, biochemical components, and color in unique green-seeded fenugreek (Trigonella foenum-graecum L.) genotypes

Frontiers in Nutrition, Год журнала: 2025, Номер 12

Опубликована: Фев. 27, 2025

Fenugreek is a high-value legume known for its potential to enhance human health and combat variety of diseases metabolic disorders. This versatile crop has demonstrated promising therapeutic effects in managing obesity, diabetes, cancer, poor metabolism conditions that have become major global concerns. Despite the availability multiple pharmaceutical remedies these ailments market, often times heavy chemical doses are accompanied by side on body. To investigate agronomic traits, medicinal potential, color fenugreek seeds, this study was conducted identified genotypes with green seed (GSF1 GSF10), which can prevent progression aforementioned without hassle effects. Ten unique green-seeded (GSF) were compared five released varieties (yellow-seeded fenugreek; YSF1 YSF5) as check. The assessed during rabi season 3 consecutive years (2021-22 2023-24) semi-arid Eastern Plain Zone Rajasthan, India. findings exhibited agronomically GSF performed well, almost at par YSF. Harvest index (23.21 ± 0.37%) higher very marginal differences other traits. showed GSF6 nearly 1.5 2 insulinotropic 4-hydroxyisoleucine (0.90%) levels YSF genotypes. non-protein branched amino acid found seeds. GSF1 high concentration chlorophyll (0.45 mg/100 g), GSF10 low diosgenin 4-OHIle (261.80 g 0.85%, respectively), GSF9 total soluble sugars (TSS; 3.50%). Oil content, phenols, proteins be making it preferable over further revealed darkness directly related content associated lower TSS. Among studied genotypes, harvest maximum yield (2473.74 Kg/ha) genotype GSF8. superior GSF1, GSF6, GSF8, GSF9, developed hold future breeding initiatives, aimed boosting value, nutritional quality, productivity.

Язык: Английский

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Fenugreek bioactive compounds: A review of applications and extraction based on emerging technologies

Critical Reviews in Food Science and Nutrition, Год журнала: 2023, Номер 64(28), С. 10187 - 10203

Опубликована: Июнь 11, 2023

AbstractFenugreek (Trigonella foenum-graecum L.) is a pharmaceutically significant aromatic crop with health benefits linked to its phytochemicals. This article aims overview progress in using emerging technologies extract bioactive compounds and extraction mechanisms. Also, the trends applications of this herb food industry therapeutical effects were explained. Fenugreek's flavor primary reason for industry. At same time, it has antimicrobial, antibacterial, hepatoprotection, anticancer, lactation, antidiabetic effects. Phytochemicals responsible these include galactomannans, saponins, alkaloids, polyphenols. Besides, data showed that boost fenugreek extracts' yield biological activity. Among these, ultrasound (55.6%) most studied technology, followed by microwave (37.0%), cold plasma (3.7%), combined approaches (3.7%). Processing conditions (e.g., treatment time intensity) solvent (type, ratio, concentration) are parameters affect performance novel technologies. Extracts obtained sustainable energy-saving can be used develop value-added health-promoting products.HIGHLIGHTSFenugreek's phytochemicals galactomannans polyphenols) have therapeutic effectsUltrasound major fenugreek's compound extractionEmerging enhance activities extractsEmerging fenugreek-based products benefitsKeywords: Trigonella foenum-graecumextractsemerging techniquesphytochemicalstherapeutic Disclosure statementNo potential conflict interest was reported authors.Additional informationFundingThe author(s) there no funding associated work featured article.

Язык: Английский

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Application of fenugreek in ruminant feed: implications for methane emissions and productivity

PeerJ, Год журнала: 2024, Номер 12, С. e16842 - e16842

Опубликована: Янв. 31, 2024

Background Human demand for meat and dairy products will increase as a result of economic development population growth, the farming ruminants, such cattle sheep, also increase. Methane (CH 4 ) emission from enteric fermentation ruminant livestock is major source greenhouse gas emissions significant contributor to global warming. Meanwhile, growth performance often limited animals are more vulnerable diseases in high-density, intensive farming, greatly reducing productivity, so developing ways reduce CH improve productivity has become research hotspot. Studies have reported that fenugreek ( Trigonella foenum-graecum L.) feed additives potential methane productivity. However, systematic reviews studies lacking. Methodology In this review, databases Google Scholar, Web Science, PubMed, Scopus Science Direct were used literature search. The initial keywords search was or L. For focused search, we added terms methane, rumen fermentation, milk production antioxidants. All done ruminants. conforms theme article selected, summarized, finally completed article. Results By regulating microbiome (suppressing protozoans, methanogenic bacteria, fungi), can lower according many vitro anaerobic experiments. Fenugreek secondary metabolites (saponins tannins) responsible impact, but it still unclear exactly how they work. Therefore, long-term vivo experiments needed verify its efficacy. rich alkaloids, amino acids, flavonoids, saponins phenolic acids. These compounds been shown beneficial effects on lactation, total antioxidant capacity. great opportunity develop into new green additive. Conclusions This review provides summary effect bioactive by addition, based available data, possible biochemical pathway ruminants described. Overall, industry natural, environmentally-friendly fenugreek.

Язык: Английский

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Application of edible nanocomposites from chitosan/fenugreek seed mucilage/selenium nanoparticles for protecting lemon from green mold

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 273, С. 133109 - 133109

Опубликована: Июнь 12, 2024

Язык: Английский

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