Pomegranate: historical origins, nutritional composition, health functions and processing development research

Critical Reviews in Food Science and Nutrition, Год журнала: 2025, Номер unknown, С. 1 - 23

Опубликована: Май 6, 2025

Pomegranate, native to Iran and Central Asia, has a long history of cultivation widespread dissemination through trade. Its extensive geographic distribution highlights its ecological adaptability economic importance. The fruit contains about 80% water, 12-20% carbohydrates, 10-60 mg dietary fiber per 100 g. It is rich in vitamins, including vitamin C, potassium, folate. Pomegranate also bioactive compounds like polyphenols, flavonoids, triterpenes, tannins, which contribute antioxidant, anti-inflammatory, antimicrobial, antiviral properties. concentration varies by genotype environmental conditions, with Punicalagin ranging from 16.67 245.47 mg/g Ellagic acid between 0.44 3.04 mg/g. Genotypic variations significantly influence the potential. Historically consumed as fresh or juice, pomegranate's by-products, such peels leaves, contain compounds. Recent research expanded applications pharmaceuticals, cosmetics, high-tech industries, promoting sustainable resource utilization. This review provides an overview cultivation, composition, substances, advancements for further development.

Язык: Английский

Dietary Flaxseed Oil and Its Blended Oil Alleviate High-Fat Diet-Induced Obesity in Mice by Improving Lipid Metabolism and Regulating Gut Microbiota

Foods, Год журнала: 2025, Номер 14(11), С. 1877 - 1877

Опубликована: Май 26, 2025

Obesity represents a chronic metabolic disorder feature by dysregulated glucose-lipid homeostasis. We investigated the effects of flaxseed oil (FO), rich in α-linolenic acid, and its blended (BO) on high-fat diet-induced obese mice. In BO, mass ratio oil, sunflower (as source linoleic acid), olive oleic acid) was precisely set at 11.90:51.64:36.46 (w/w/w) After 13 weeks supplementation, both FO BO significantly suppressed weight gain (multiple comparisons week 13: 8.57 ± 1.25 g ND group; 25.08 2.96 HFD 19.35 1.47 g/19.71 HFD+FO/HFD+BO group), fat accumulation, restored dyslipidemia (notably, administration resulted significant reduction LDL-C LEP levels (p < 0.01)), elevated blood glucose (FO demonstrated more pronounced effect compared to BO), liver tissue damage (specifically, exhibited decreasing oxidative stress markers, including alanine aminotransferase (ALT) malondialdehyde (MDA), greater efficacy ameliorating histopathological conditions tissue) HFD-fed The 16S rRNA gene sequencing mice fecal samples showed that reduced Firmicutes/Bacteroidetes (F/B) (supplementation with decreased F/B from 68.95 15.24 0.01), while supplementation it 19.47), abundance Proteobacteria 0.21 0.15, whereas 0.17). addition, increased Clostridium, Lactobacillus (rose 5.42 10.3), reversing imbalance gut microbiota These findings suggest may be promising dietary strategies for treating obesity improving associated disorders.

Язык: Английский

Analysis of diagnostic genes and molecular mechanisms of Crohn’s disease and colon cancer based on machine learning algorithms

Scientific Reports, Год журнала: 2024, Номер 14(1)

Опубликована: Дек. 30, 2024

Язык: Английский