Protective effects of tiger milk mushroom extract (xLr®) against UVB irradiation in Caenorhabditis elegans via DAF-16 anti-oxidant regulation DOI Creative Commons
Panthakarn Rangsinth,

Rajasekharan Sharika,

Chanin Sillapachaiyaporn

и другие.

Journal of Traditional and Complementary Medicine, Год журнала: 2024, Номер 15(1), С. 73 - 83

Опубликована: Ноя. 12, 2024

A critical causative factor of oxidative stress and inflammation leading to several skin complications is ultraviolet-B (UVB) irradiation. Lignosus rhinocerus (LR), or tiger milk mushroom, native Southeast Asia. Cold water extract an LR cultivar, TM02® (xLr®) a promising anti-oxidant anti-inflammatory source. However, the effects xLr® on UVB-induced photoaging have never been elucidated. This study investigated protective its high, medium, low molecular weight (HLR, MLR, LLR, respectively) fractions against UVB irradiation using in vivo Caenorhabditis elegans (C. elegans) model. The investigation revealed significant lifespan extension UVB-irradiated C. elegans, which could be mediated by regulation genes associated with (daf-16 sod-3) apoptosis (cep-1, hus-1, ced-13, egl-1) pathways. significantly reduced ROS production increased DAF-16 nuclear translocation compared untreated worms. Additionally, SOD-3 expression was xLr®-treated Hence, it suggests that different components work synergistically protect Our findings may beneficial for application as treatment cellular damage photoaging.

Язык: Английский

Green Synthesis of Zinc Oxide Nanoparticles for the Industrial Biofortification of (Pleurotus pulmonarius) Mushrooms DOI Creative Commons

Muhammad Bin Ali,

Tehreema Iftikhar, Hammad Majeed

и другие.

Heliyon, Год журнала: 2024, Номер 10(19), С. e37927 - e37927

Опубликована: Сен. 19, 2024

Язык: Английский

Процитировано

3
Protective effects of tiger milk mushroom extract (xLr®) against UVB irradiation in Caenorhabditis elegans via DAF-16 anti-oxidant regulation DOI Creative Commons
Panthakarn Rangsinth,

Rajasekharan Sharika,

Chanin Sillapachaiyaporn

и другие.

Journal of Traditional and Complementary Medicine, Год журнала: 2024, Номер 15(1), С. 73 - 83

Опубликована: Ноя. 12, 2024

A critical causative factor of oxidative stress and inflammation leading to several skin complications is ultraviolet-B (UVB) irradiation. Lignosus rhinocerus (LR), or tiger milk mushroom, native Southeast Asia. Cold water extract an LR cultivar, TM02® (xLr®) a promising anti-oxidant anti-inflammatory source. However, the effects xLr® on UVB-induced photoaging have never been elucidated. This study investigated protective its high, medium, low molecular weight (HLR, MLR, LLR, respectively) fractions against UVB irradiation using in vivo Caenorhabditis elegans (C. elegans) model. The investigation revealed significant lifespan extension UVB-irradiated C. elegans, which could be mediated by regulation genes associated with (daf-16 sod-3) apoptosis (cep-1, hus-1, ced-13, egl-1) pathways. significantly reduced ROS production increased DAF-16 nuclear translocation compared untreated worms. Additionally, SOD-3 expression was xLr®-treated Hence, it suggests that different components work synergistically protect Our findings may beneficial for application as treatment cellular damage photoaging.

Язык: Английский

Процитировано

0