Anti-proliferative effects of Rosmarinus officinalis L. (Rosemary) against human breast and liver carcinoma cells
Food Bioscience,
Год журнала:
2025,
Номер
unknown, С. 106164 - 106164
Опубликована: Фев. 1, 2025
Язык: Английский
Comprehensive review of extraction, purification, structural characteristics, pharmacological activities, structure-activity relationship and application of seabuckthorn protein and peptides
Guo Chun-qiu,
Ling Na,
Haiyan Tian
и другие.
International Journal of Biological Macromolecules,
Год журнала:
2025,
Номер
294, С. 139447 - 139447
Опубликована: Янв. 5, 2025
Язык: Английский
Research Progress on Anti-Hyperlipidemia Peptides Derived from Foods
Nutrients,
Год журнала:
2025,
Номер
17(7), С. 1181 - 1181
Опубликована: Март 28, 2025
Hyperlipidemia
is
a
metabolic
disorder
in
which
cholesterol
(TC)
and
triglycerides
(TGs)
the
blood
exceed
normal
physiological
levels.
The
incidence
of
condition
has
continued
to
rise
recent
years,
posing
serious
threat
public
health.
Its
clinical
treatment
mainly
relies
on
drug
interventions,
such
as
statins,
fibrate,
niacin.
Although
these
drugs
have
shown
some
efficacy
hyperlipidemia,
their
adverse
effects
cannot
be
ignored.
In
contrast,
naturally
derived
peptides
gradually
become
potential
candidates
for
prevention
hyperlipidemia
due
strong
anti-hyperlipidemic
activity
safety;
examples
include
those
from
dairy
products,
grains,
legumes,
seafood.
This
review
systematically
summarizes
with
analyzes
mechanisms
action,
providing
theoretical
basis
further
research.
addition,
we
also
outline
challenges
facing
application
peptides,
hoping
prevent
reduce
its
by
encouraging
consumption
foods
rich
anti-hyperlipidemia
peptides.
Язык: Английский
Food-grade Lactococcus lactis expressing LEK peptide ameliorates hypertension and hyperlipidemia via ACE inhibition and lipid metabolism regulation
Journal of Functional Foods,
Год журнала:
2025,
Номер
129, С. 106830 - 106830
Опубликована: Апрель 29, 2025
Язык: Английский
Macadamia (Macadamia integrifolia) Oil Prevents High-Fat Diet-Induced Lipid Accumulation and Oxidative Stress by Activating the AMPK/Nrf2 Pathway
Foods,
Год журнала:
2024,
Номер
13(22), С. 3672 - 3672
Опубликована: Ноя. 18, 2024
Hyperlipidemia,
characterized
by
an
abnormal
lipid
metabolism,
is
related
to
multiple
cardiovascular
diseases
that
pose
challenges
global
public
health.
Macadamia
oil
(MO),
rich
in
monounsaturated
fatty
acids
(around
80%),
regarded
as
a
functional
used
regulate
accumulation.
Nonetheless,
the
lipid-lowering
mechanism
of
MO
still
unknown.
Therefore,
effects
high-fat
diet
(HFD)-induced
hyperlipidemic
mice
were
evaluated
this
study.
The
results
revealed
could
effectively
reduce
body
weight
and
organ
index
improve
serum
levels
reducing
total
cholesterol,
triglycerides,
low-density
lipoprotein
cholesterol
elevating
high-density
levels.
Additionally,
supplementation
liver
function
caused
hyperlipemia,
decreased
enzyme
levels,
including
alanine
aminotransferase
aspartate
aminotransferase.
Meanwhile,
also
exhibited
inhibitory
effect
on
oxidative
stress
accumulation
HFD.
Moreover,
findings
from
qRT-PCR
Western
blotting
analyses
suggest
markedly
prevented
hyperlipidemia
inhibiting
expression
AMPK
pathway-related
genes,
SREBP-1c,
FAS,
ACC,
PPAR-γ,
well
upregulating
Nrf2,
HO-1,
γ-GCS.
These
indicate
attenuates
vivo
via
AMPK/Nrf2
pathway
activation,
suggesting
serve
dietary
or
medication
for
treating
hyperlipidemia.
Язык: Английский