Citrus Pomace as a Source of Plant Complexes to Be Used in the Nutraceutical Field of Intestinal Inflammation DOI Creative Commons

Mariarosaria Ingegneri,

Maria Rita Braghini,

Michela Piccione

и другие.

Antioxidants, Год журнала: 2024, Номер 13(7), С. 869 - 869

Опубликована: Июль 19, 2024

This study aims to recover the main by-product of Citrus fruits processing, raw pomace, known also as pastazzo, produce plant complexes be used in treatment inflammatory bowel disease (IBD). Food-grade extracts from orange (OE) and lemon (LE) pomace were obtained by ultrasound-assisted maceration. After a preliminary phytochemical biological screening vitro assays, primary secondary metabolites characterized proton nuclear magnetic resonance (1H-NMR) liquid chromatography coupled diode array detection electrospray ionization mass spectrometry (LC-DAD-ESI-MS) analyses. The intestinal bioaccessibility antioxidant anti-inflammatory properties investigated simulated gastro-intestinal digestion followed treatments on lipopolysaccharide (LPS)-stimulated human colorectal adenocarcinoma cell line (Caco-2). tight junctions-associated structural proteins (ZO-1, Claudin-1, Occludin), transepithelial electrical resistance (TEER), reactive oxygen species (ROS)-levels, expression some key (CAT, NRF2 SOD2) (IL-1β, IL-6, TNF-α, IL-8) genes, pNFkB p65 translocation, evaluated. OE LE digesta, which did not show any significant difference terms profile, showed effects protecting against LPS-induced barrier damage, oxidative stress response. In conclusion, both emerged potential candidates for further preclinical studies vivo IBD models.

Язык: Английский

The Effect of the Use of Unconventional Solutions for Osmotic Dehydration on Selected Properties of Fresh-Cut Oranges DOI Creative Commons
Sabina Galus, Katarzyna Rybak, Magdalena Dadan

и другие.

Foods, Год журнала: 2025, Номер 14(3), С. 468 - 468

Опубликована: Фев. 1, 2025

This study investigated the effects of unconventional solutions on osmotic dehydration oranges. These included xylitol, fruit concentrates (strawberry, cherry, orange), rosehip juice, and sucrose. The examined kinetics, dry matter, total soluble solids, water activity, color, texture, sugars, vitamin C, polyphenols, carotenoids, antioxidant potential, alongside microstructural observations. results indicated that time (3 h) significantly influenced oranges’ physical chemical properties. Cherry strawberry concentrate caused greatest color changes, enhancing dried product’s visual appeal. Oranges dehydrated with exhibited highest polyphenol content (2909 mg chlorogenic acid/100 g d.m.) potential (11.0 TE/d.m.), while solution yielded C levels (80.27 g/100 d.m.), followed by (62.32 orange (47.67 concentrates. findings highlight benefits using juices in dehydration. resulted a reduction hardness sliced from 0.65 N to range 0.36–0.60 N, except for concentrate, which value (0.72 N). Key parameters, such as efficiency, were more favorable compared those sucrose samples. organoleptic assessment recommended xylitol maintaining sweetness without altering taste or smell, whereas juice scored lowest due its foreign smell. Overall, enhanced nutritional sensory attributes oranges allowing penetration bioactive compounds, making them superior fresh raw material tested parameters.

Язык: Английский

Процитировано

0

Effect of microwave and ultrasonic pre-treatments on anaerobic co-digestion of orange wastes and municipal sewage sludge: A case study DOI Creative Commons
Aleksandra Szaja, Izabela Bartkowska

Desalination and Water Treatment, Год журнала: 2024, Номер 320, С. 100754 - 100754

Опубликована: Сен. 4, 2024

Язык: Английский

Процитировано

2

Citrus Pomace as a Source of Plant Complexes to Be Used in the Nutraceutical Field of Intestinal Inflammation DOI Creative Commons

Mariarosaria Ingegneri,

Maria Rita Braghini,

Michela Piccione

и другие.

Antioxidants, Год журнала: 2024, Номер 13(7), С. 869 - 869

Опубликована: Июль 19, 2024

This study aims to recover the main by-product of Citrus fruits processing, raw pomace, known also as pastazzo, produce plant complexes be used in treatment inflammatory bowel disease (IBD). Food-grade extracts from orange (OE) and lemon (LE) pomace were obtained by ultrasound-assisted maceration. After a preliminary phytochemical biological screening vitro assays, primary secondary metabolites characterized proton nuclear magnetic resonance (1H-NMR) liquid chromatography coupled diode array detection electrospray ionization mass spectrometry (LC-DAD-ESI-MS) analyses. The intestinal bioaccessibility antioxidant anti-inflammatory properties investigated simulated gastro-intestinal digestion followed treatments on lipopolysaccharide (LPS)-stimulated human colorectal adenocarcinoma cell line (Caco-2). tight junctions-associated structural proteins (ZO-1, Claudin-1, Occludin), transepithelial electrical resistance (TEER), reactive oxygen species (ROS)-levels, expression some key (CAT, NRF2 SOD2) (IL-1β, IL-6, TNF-α, IL-8) genes, pNFkB p65 translocation, evaluated. OE LE digesta, which did not show any significant difference terms profile, showed effects protecting against LPS-induced barrier damage, oxidative stress response. In conclusion, both emerged potential candidates for further preclinical studies vivo IBD models.

Язык: Английский

Процитировано

1