Eucalyptol alleviates avermectin exposure-induced apoptosis and necroptosis of grass carp hepatocytes by regulating ROS/NLRP3 axis

Aquatic Toxicology, Год журнала: 2023, Номер 264, С. 106739 - 106739

Опубликована: Окт. 30, 2023

Язык: Английский

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Imidacloprid affects human cells through mitochondrial dysfunction and oxidative stress

The Science of The Total Environment, Год журнала: 2024, Номер 951, С. 175422 - 175422

Опубликована: Авг. 13, 2024

Язык: Английский

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ROS acted as an initial role in selenium nanoparticles alleviating insecticide chlorpyrifos-induced oxidative stress, pyroptosis, and intestinal barrier dysfunction in porcine intestinal epithelial cells

Pesticide Biochemistry and Physiology, Год журнала: 2025, Номер 211, С. 106418 - 106418

Опубликована: Апрель 16, 2025

Язык: Английский

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Resveratrol improves emamectin benzoate-induced pyroptosis and inflammation of Ctenopharyngodon idellus hepatic cells by alleviating oxidative stress/endoplasmic reticulum stress

Fish & Shellfish Immunology, Год журнала: 2023, Номер 142, С. 109148 - 109148

Опубликована: Окт. 6, 2023

Язык: Английский

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Resveratrol alleviates Mono-2-ethylhexyl phthalate-induced mitophagy, ferroptosis, and immunological dysfunction in grass carp hepatocytes by regulating the Nrf2 pathway

Journal of Environmental Management, Год журнала: 2024, Номер 371, С. 123235 - 123235

Опубликована: Ноя. 6, 2024

Язык: Английский

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New insights into resveratrol attenuates hepatotoxicity in emamectin benzoate-exposed grass carp (Ctenopharyngodon idella) via NO system/NF-κB signaling pathway

Pesticide Biochemistry and Physiology, Год журнала: 2024, Номер 202, С. 105941 - 105941

Опубликована: Май 3, 2024

Язык: Английский

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Trimethyltin chloride induces apoptosis and DNA damage via ROS/NF-κB in grass carp liver cells causing immune dysfunction

Fish & Shellfish Immunology, Год журнала: 2023, Номер 142, С. 109082 - 109082

Опубликована: Сен. 24, 2023

Язык: Английский

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Chronic exposure to environmentally relevant concentration of abamectin induces gut toxicity in largemouth bass: Molecular fate, bioaccumulation risk and its potential phytoremediation

Environmental Chemistry and Ecotoxicology, Год журнала: 2025, Номер unknown

Опубликована: Май 1, 2025

Язык: Английский

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Emamectin benzoate and nanoplastics induce PANoptosis of common carp (Cyprinus carpio) gill through MAPK pathway

Pesticide Biochemistry and Physiology, Год журнала: 2024, Номер 206, С. 106202 - 106202

Опубликована: Ноя. 2, 2024

Язык: Английский

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Exposure to Trimethyltin Chloride Induces Pyroptosis and Immune Dysfunction in Grass Carp CIK Cells by Activating the NF‐κB Pathway Through Oxidative Stress

Environmental Toxicology, Год журнала: 2024, Номер 39(11), С. 4984 - 4994

Опубликована: Июль 14, 2024

ABSTRACT Trimethyltin chloride (TMT) is a highly toxic organotin pollutant frequently found in aquatic environments, posing significant threat to the ecological system. The kidney plays vital role body's detoxification processes, and TMT present environment tends accumulate kidneys. However, it remained unclear whether exposure different doses of could induce pyroptosis immune dysfunction grass carp cells (CIK cells). For this purpose, after assessing half‐maximal inhibitory concentration (IC50) on CIK cells, we established model for at varying concentrations TMT. were treated with various (2.5, 5, 10 μM) 24 h. Oxidative stress levels measured using kits fluorescence methods, whereas expression related genes was verified through western blot quantitative real‐time PCR (qRT‐PCR). results indicated that led oxidative stress, increased ROS, H 2 O , MDA, GSH, inhibited activities T‐AOC, SOD, CAT. It activated NF‐κB pathway, leading upregulation p65, p50, GSDMD, NLRP3, ASC, Caspase‐1. Furthermore, also resulted cytokines (IL‐18, IL‐6, IL‐2, IL‐1β, TNF‐α) decreased antimicrobial peptides (LEAP2, HEPC, β‐defensin). In summary, induces dose‐dependent activates cells.

Язык: Английский

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