The intrinsic macrolide resistome of Escherichia coli
Antimicrobial Agents and Chemotherapy,
Год журнала:
2024,
Номер
68(8)
Опубликована: Июнь 28, 2024
Intrinsic
resistance
to
macrolides
in
Gram-negative
bacteria
is
primarily
attributed
the
low
permeability
of
outer
membrane,
though
underlying
genetic
and
molecular
mechanisms
remain
be
fully
elucidated.
Here,
we
used
transposon
directed
insertion-site
sequencing
(TraDIS)
identify
chromosomal
non-essential
genes
involved
Язык: Английский
Cryptic Mutation in the Genome of Salmonella enterica to Acquire AMR Genes With Alteration of Amino Acid Sequences: A Pathogenomics Study
Biotechnology and Applied Biochemistry,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 21, 2025
ABSTRACT
The
Mahanadi
river
is
a
freshwater
sink
of
Odisha
which
has
taken
its
course
through
the
Western
and
finally
end
in
Bay
Bengal.
However,
water
receiving
pathogenic
bacterial
strains
due
to
anthropogenic
activities
therefore
health
common
man
severely
affected
with
regular
outbreaks.
This
present
pursuit
had
aimed
carry
out
pathogenomics
isolate
perpetuating
said
near
local
tertiary
care
hospital,
Burla,
Odisha,
India.
Relevant
procedures
experiments
were
carried
out,
strain
Salmonella
enterica
was
identified.
whole
genome
sequenced
using
NGS
approaches.
It
observed
that
there
alteration
amino
acids
leading
acquire
AMR
genes.
There
change
nucleotide
codon
from
CTA
reversed
back
CTA,
acid
I
>
P,
position
contig,
143183–146332
at
node
15,
eluted
gene
acrB
identity
99.97%.
In
addition,
AGC
ACC
T
S
17
elution
genes,
pmrA
(109013‐10968)
pmrB
(109691–110761)
contig.
further
depiction
ATG
ACG,
GTC
GCC,
GGC
AGC,
GTA
ATA,
ATT
GTT,
GCG
ACG.
As
result
which,
methionine
threonine
(M
T),
valine
alanine
(V
A),
glycine
serine
(G
S),
isoleucine
I),
(I
V),
(A
T)
changed
without
any
respect
consociation.
Язык: Английский
CRISPR/Cas12a-Triggered Visible-Light-Driven Photoelectrochemical Assay with Single-Nucleotide Resolution for Drug-Resistant Foodborne Salmonella Detection
Jun Li,
Jiaen Song,
Yanbai Chen
и другие.
Journal of Agricultural and Food Chemistry,
Год журнала:
2024,
Номер
unknown
Опубликована: Сен. 19, 2024
The
prevalence
of
foodborne
pathogenic
bacteria,
especially
drug-resistant
strains,
such
as
Язык: Английский