Electrochemical Enaminone-Thioamide Annulation and Thioamide Dimeric Annulation for the Tunable Synthesis of Thiazoles and 1,2,4-Thiadiazole

Organic Letters, Год журнала: 2024, Номер 26(25), С. 5263 - 5268

Опубликована: Июнь 14, 2024

A green and sustainable electrochemical oxidative cyclization of enaminones with thioamides under metal- oxidant-free conditions has been developed, providing an efficient approach for thiazole synthesis. Furthermore, 1,2,4-thiadiazoles can be selectively accessed via the dimerization in absence enaminones.

Язык: Английский

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Photocatalytic Minisci-type multicomponent reaction for the synthesis of 1-(halo)alkyl-3-heteroaryl bicyclo[1.1.1]pentanes

Chinese Chemical Letters, Год журнала: 2024, Номер 35(10), С. 110115 - 110115

Опубликована: Июнь 13, 2024

Язык: Английский

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Electrosynthesis of N/S-Heterocycles

Green Chemistry, Год журнала: 2024, Номер 26(13), С. 7532 - 7551

Опубликована: Янв. 1, 2024

In this review, we present a comprehensive overview of our recent advancements in the methodology electrochemically assisted radical generation and its subsequent application synthesis functionalization diverse N/S-heterocyclic compounds.

Язык: Английский

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Progress on direct transformation of thiols to sulfinyl compounds

Phosphorus, sulfur, and silicon and the related elements, Год журнала: 2025, Номер unknown, С. 1 - 9

Опубликована: Янв. 26, 2025

Язык: Английский

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Native α‐ and β‐Cyclodextrin Cobalt Complexes as Catalysts in Sulfoxidation Reaction

ChemistrySelect, Год журнала: 2025, Номер 10(16)

Опубликована: Апрель 1, 2025

Abstract Four complexes were synthesised between bromide cobalt salt and native α‐ β‐cyclodextrins using dichloromethane or ethyl acetate as solvents. These characterised by techniques such IR, TGA UV–vis diffuse reflectance. used catalysts in the sulfoxidation reaction, being β‐CD/CoBr 2(DCM) is more efficient complex. The reaction conditions studied yielded good results with high chemoselectivity, aldehyde sulfoxide functional groups not oxidized under these conditions. evaluation green chemistry parameters showed results. use of EtOAc, a solvent, synthesis highlighted.

Язык: Английский

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A General Photoactive H‐Bonding EDA Complex Model Drives the Selective Hydrothiolation and Hydroxysulfenylation of Carbonyl Activated Alkenes

Angewandte Chemie International Edition, Год журнала: 2024, Номер 63(38)

Опубликована: Июль 2, 2024

Excitation of photoactive electron donor-acceptor (EDA) complexes to generate radical is a promising approach in chemistry. In this study, we introduce new model H-bonding EDA for the selective hydrothiolation and hydroxysulfenylation carbonyl-activated alkenes with diverse thiols under visible light conditions. The reliability complex has been confirmed by meticulous experimental theoretical calculations. Mechanistic investigations have revealed significant influence solvent determining whether excitation leads charge transfer (CT) or energy-charge (E

Язык: Английский

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Electrochemical multicomponent reaction toward vicinal sulfenyltetrazolation of unactivated alkenes

Organic Chemistry Frontiers, Год журнала: 2023, Номер 10(20), С. 5064 - 5069

Опубликована: Янв. 1, 2023

An electrochemical multicomponent reaction (e-MCR) enables the green and sustainable preparation of diverse vicinal sulfenyltetrazolation using readily available unactivated olefins, thiols, azidotrimethylsilane, acetonitrile.

Язык: Английский

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Electrochemical β-chlorosulfoxidation of alkenes

Organic Chemistry Frontiers, Год журнала: 2022, Номер 9(20), С. 5586 - 5591

Опубликована: Янв. 1, 2022

A green and sustainable electrochemical β-chlorosulfoxidation of alkenes with readily available thiols hydrochloride as the limiting agents has been developed.

Язык: Английский

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A General Photoactive H‐Bonding EDA Complex Model Drives the Selective Hydrothiolation and Hydroxysulfenylation of Carbonyl Activated Alkenes

Angewandte Chemie, Год журнала: 2024, Номер 136(38)

Опубликована: Июль 2, 2024

Abstract Excitation of photoactive electron donor−acceptor (EDA) complexes to generate radical is a promising approach in chemistry. In this study, we introduce new model H‐bonding EDA for the selective hydrothiolation and hydroxysulfenylation carbonyl‐activated alkenes with diverse thiols under visible light conditions. The reliability complex has been confirmed by meticulous experimental theoretical calculations. Mechanistic investigations have revealed significant influence solvent determining whether excitation leads charge transfer (CT) or energy‐charge (E n ‐CT), thereby controlling Markovnikov anti‐Markovnikov selectivity. Notably, Quantum Theory Atoms Molecules (QTAIM) analysis clearly shows that excited state C=O−H−S involves closed‐shell partially covalent interactions.

Язык: Английский

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Electrochemically Mediated Construction and Functionalization of N/S-Heterocycles

Topics in heterocyclic chemistry, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Язык: Английский

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