Organic Letters, Год журнала: 2024, Номер unknown

Опубликована: Дек. 13, 2024

The direct carboxylation of C(sp3)–H bonds with CO2 represents a challenging but highly attractive strategy in organic synthesis. In this study, we presented visible-light-catalyzed for carboxylating remote via aryl radical induced 1,5-hydrogen atom transfer. This transformation involves generating alkyl radicals transfer from radicals, forming carbanions as key intermediates, and subsequent nucleophilic attack CO2, thereby enabling access to variety tertiary quaternary carboxylic acids moderate good yields.

Язык: Английский