Deleted Journal, Год журнала: 2025, Номер 2(1)
Опубликована: Янв. 21, 2025
Язык: Английский
The Science of The Total Environment, Год журнала: 2024, Номер 931, С. 172687 - 172687
Опубликована: Апрель 23, 2024
Язык: Английский
Процитировано
17
Aquaculture International, Год журнала: 2024, Номер 32(6), С. 7671 - 7681
Опубликована: Май 9, 2024
Abstract Aquaculture faces significant challenges due to bacterial pathogens like Aeromonas hydrophila , which can severely impact production and fish health. Understanding the relationship between environmental factors, host susceptibility, virulence is crucial for effectively managing mitigating risks associated with A. in aquaculture systems. found ubiquitously aquatic environments, possesses various factors that enhance its pathogenicity. These are closely linked conditions, such as temperature pH, play pivotal roles growth, survival, pathogenic potential. Fluctuations pH significantly influence ’s metabolic activity growth rate, thereby modulating overall Ammonia, a byproduct of organism metabolism organic matter decomposition, accumulate toxic levels settings, compromising health immune function. Elevated ammonia concentrations worsen infections by immunity creating favorable conditions proliferation. Oxygen concentration, signals, diet formulation impacting susceptibility organisms infection. most shaping ecology, physiology, pathogenicity aquaculture. There limited information on how these modulate genes important pathogens. The knowledge interplay paves way developing strategies prevent control diseases
Язык: Английский
Процитировано
14
Foods, Год журнала: 2024, Номер 13(23), С. 3886 - 3886
Опубликована: Дек. 1, 2024
Foodborne pathogens are microorganisms that cause illness through contamination, presenting significant risks to public health and food safety. This review explores the metabolites produced by these pathogens, including toxins secondary metabolites, their implications for human health, particularly concerning cancer risk. We examine various such as Salmonella sp., Campylobacter Escherichia coli, Listeria monocytogenes, detailing specific of concern carcinogenic mechanisms. study discusses analytical techniques detecting chromatography, spectrometry, immunoassays, along with challenges associated detection. covers effective control strategies, processing techniques, sanitation practices, regulatory measures, emerging technologies in pathogen control. manuscript considers broader highlighting importance robust policies, awareness, education. identifies research gaps innovative approaches, recommending advancements detection methods, preventive policy improvements better manage foodborne metabolites.
Язык: Английский
Процитировано
13
Vaccines, Год журнала: 2025, Номер 13(2), С. 202 - 202
Опубликована: Фев. 18, 2025
Aeromonas hydrophila presents a significant threat to global aquaculture due its ability infect freshwater and marine fish species, leading substantial economic losses. Effective mitigation methods are essential address these challenges. Vaccination has emerged as promising strategy reduce A. infections; however, it faces several obstacles, including variability in immune responses, pathogen diversity, environmental factors affecting vaccine efficacy. To enhance performance, researchers focus on adjuvants boost responses develop multivalent vaccines targeting multiple strains. Tailoring specific conditions optimizing vaccination schedules can further the challenges posed by diversity variable responses. This review provides an in-depth analysis of immunological hurdles associated with development. Current types-live attenuated, inactivated, subunit, recombinant, DNA-exhibit diverse mechanisms for stimulating innate adaptive immunity, varying levels success. Key areas include potential advanced nanoparticle delivery systems overcome existing barriers. The also highlights importance understanding host-pathogen interactions guiding development more targeted effective fish. Complementary approaches, such immunostimulants, probiotics, plant-based extracts, explored adjuncts health management. Despite notable progress, remain translating laboratory innovations into scalable, cost-effective solutions aquaculture. Future directions emphasize integration genomic proteomic tools identify novel antigen candidates need industry-wide collaborations standardize production delivery. Addressing unlock innovative technologies safeguard promote sustainable practices globally.
Язык: Английский
Процитировано
2
Frontiers in Immunology, Год журнала: 2024, Номер 15
Опубликована: Май 10, 2024
Introduction Aeromonas hydrophila , a bacterium widely distributed in the natural environment, causes multiple diseases various animals. Exploring mechanism of host defense against A. can help develop efficient strategies infection. Methods Herein, we investigated temporal influence on Chinese soft-shelled turtle, an economically important species, at biochemical, transcriptomic, and metabolomic levels. Plasma parameters were detected with test kits. Transcriptome metabolome respectively applied to screen differentially expressed genes metabolites. Results The contents or activities these plasma significantly increased 24 hpi declined 96 hpi, indicating that two time points during Totals 3121 274 (DEGs) from transcriptome while 74 91 abundant metabolites (DAMs) hpi. top DEGs included Ccl2, Ccl3, Ccl4, Il1β, Il6, Il7, Il15, Tnf, Tnfr1 Zap70, Cd3g, Cd8a, Itk, Pik3r3, Cd247, Malt1, Cd4 most predominant DAMs O-phospho-L-serine, γ-Aminobutyric acid, orotate, L-tyrosine, L-tryptophan as well L-glutamic L-arginine, glutathione, glutathione disulfide, citric acid Discussion combined analysis revealed tryptophan metabolism, nicotinate nicotinamide starch sucrose signaling pathways early infective stage tyrosine pyrimidine alanine, aspartate glutamate metabolism crucial later stage. In general, our results indicated turtle displays stage-specific physiological responses resist
Язык: Английский
Процитировано
9
Archives of Microbiology, Год журнала: 2024, Номер 206(5)
Опубликована: Апрель 16, 2024
Язык: Английский
Процитировано
8
Advances in environmental engineering and green technologies book series, Год журнала: 2024, Номер unknown, С. 297 - 318
Опубликована: Май 1, 2024
Secondary metabolites produced by plants are particular to their species or genus and do not contribute the basic processes of growth, development, reproduction. These compounds play a key role as feed deterrents against herbivores, protectants from microbial infection, abiotic stresses, UV-protectants, pollinators attractants, antioxidants, signalling molecules. Based on chemical structures production routes, secondary may be further classified across several classes. Alkaloids, terpenes, phenolic chemicals make up largest most common group. The importance found in for human nutrition has grown an important interesting research area. used people medicine cure illnesses infections, flavourings, pesticides recent past. Therefore, overview is provided this chapter including how these relevant health.
Язык: Английский
Процитировано
8
Aquaculture, Год журнала: 2024, Номер 588, С. 740943 - 740943
Опубликована: Апрель 9, 2024
Язык: Английский
Процитировано
7
Scientific Reports, Год журнала: 2024, Номер 14(1)
Опубликована: Июль 23, 2024
Several farmed fish species, including carps, tilapia, salmon, and catfish, have experienced significant economic losses in aquaculture due to motile Aeromonas septicemia caused by hydrophila. In the present study, a novel lytic bacteriophage infecting hypervirulent hydrophila (vAh) was isolated characterized. This is first report of phage against vAh. Phage AhFM11 demonstrated activity both vAh strains A. reference strain ATCC 35654. The genome sequenced assembled, comprising 168,243 bp with an average G + C content 41.5%. did not harbor any antibiotic resistance genes. Genomic information along transmission electron microscopy revealed that belongs Straboviridae family. Therapeutic application monophage showed 100% survival injection, 95% immersion 93% oral feeding top-coated feed. Fish chicken meat spiked reduction These findings support can be used as biocontrol agent alternative antibiotics.
Язык: Английский
Процитировано
7
Food Packaging and Shelf Life, Год журнала: 2025, Номер 47, С. 101437 - 101437
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
1