Advances in Clinical Medicine, Год журнала: 2024, Номер 14(05), С. 283 - 290
Опубликована: Янв. 1, 2024
Язык: Английский
ESC Heart Failure, Год журнала: 2024, Номер unknown
Опубликована: Июнь 12, 2024
Abstract Aims The value of the systemic immune‐inflammatory index (SII) in assessing adverse outcomes various cardiovascular diseases has been extensively discussed. This study aims to evaluate predictive and risk stratification ability SII for 30 day mortality patients with acute decompensated heart failure (ADHF). Methods analysis included 1452 hospitalized ADHF, all participants being part China Jiangxi‐acute failure1 project. capability as well its correlation among ADHF patients, was evaluated utilizing Kaplan–Meier survival multivariable Cox regression models. A restricted cubic spline employed model dose–response relationship between two, receiver operating characteristic curve utilized assess mortality. Results revealed that high group (SII ≥ 980 × 10 9 /L) significantly greater than low < /L, log‐rank P 0.001). After adjusting confounding factors, a higher associated an increased [hazard ratio (HR) = 2.03, 95% confidence interval (CI): 1.34–3.08]. Further non‐linear two ( 0.006). Receiver demonstrated had accuracy predicting events (AUC 0.7479), optimal threshold calculated be sensitivity 0.7547 specificity 0.7234. Conclusions found significant positive association all‐cause patients. We determined cut‐off point /L.
Язык: Английский
Процитировано
4
Genel Tıp Dergisi, Год журнала: 2025, Номер 35(1), С. 123 - 128
Опубликована: Фев. 28, 2025
Background: A new parameter called systemic immune-inflammatory index (SII), which is based on neutrophil-lymphocyte ratio (NLR) and platelet count, used to examine the inflammatory immune status of patients. The aim this study was evaluate prognostic value SII in adolescents diagnosed with COVID-19 compare other biomarkers such as C-reactive protein (CRP)/albumin (Alb) ratio, D-dimer, lactate NLR. Methods: medical records hospitalized adolescent patients between April 1, 2020, March 31, 2022, were retrospectively reviewed. cut-off for obtained predictive intensive care unit (ICU) admission primary outcome. Results: total 177 a mean age 165.89 ± 26.60 months included study. 97 (54.8%) male. most common presenting symptom fever (n:102, 57.6%). Median (IQR) 799 (951), 1.9 (1.53), NLR 10.19 6.77 CRP/Alb 1.55 (2.61). predicting ICU ≥1111 (sensitivity, 78.6%; specificity, 75.2%; +likelihood (3.32); -likelihood 0.30; AUC:0.768) (p 0.05). Conclusion: results suggest that high during hospitalization associated an increased likelihood COVID-19. Although additional studies are needed confirm validate these findings, evidence supports valuable predictor hospitilized
Язык: Английский
Процитировано
0
Discover Oncology, Год журнала: 2025, Номер 16(1)
Опубликована: Март 14, 2025
Our study aimed to examine the predictive relevance of Systemic Immune-Inflammation Index (SII) in patients with metastatic castration-resistant prostate cancer (mCRPC). A total 113 mCRPC were assessed. In this descriptive study, SII was calculated using formula (neutrophil count × platelet count)/lymphocyte count. The optimal threshold for SII, determined via ROC curve, 700. Patients ≤ 700 classified as SII-low, while those > categorized SII-high. median overall survival (mOS) significantly longer low group compared high (*P = 0.015). multivariate analysis, Gleason score, albumin levels, CHAARTED volume, and identified significant prognostic factors. findings indicate that has a strong correlation can serve an independent marker patients.
Язык: Английский
Процитировано
0
Journal of Clinical Medicine, Год журнала: 2024, Номер 13(15), С. 4466 - 4466
Опубликована: Июль 30, 2024
Background: The prognostic nutritional index (PNI) and the systemic immune inflammation (SII) have been used as simple risk-stratification predictors for COVID-19 severity mortality in general population. However, associations between these indices might differ due to age-related changes such inflammaging several comorbid conditions older patients. Therefore, we aimed compare predictivity of PNI SII among hospitalized patients under 65 years old. Methods: Patients with from March 2020 December were retrospectively included. calculated hospital records within first 48 h after admission. Data evaluated whole group according age groups (≥65 < years). Receiver operating characteristic curves drawn evaluate SII. Results: Out 407 included this study, 48.4% (n = 197) patients, 51.6% 210) For mortality, area curve (AUC) adult (<65 years) was 0.706 (95% CI 0.583–0.828) (p 0.003) 0.697 0.567–0.827) 0.005), respectively. AUC 0.515 0.427–0.604) 0.739) 0.500 0.411–0.590) 0.993). Conclusions: accuracy predicting seemed be fair, but no association found geriatric study. varies groups.
Язык: Английский
Процитировано
2
Advances in Clinical Medicine, Год журнала: 2024, Номер 14(05), С. 283 - 290
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
0