Recent Advances in Wearable Healthcare Devices: From Material to Application
Bioengineering,
Год журнала:
2024,
Номер
11(4), С. 358 - 358
Опубликована: Апрель 6, 2024
In
recent
years,
the
proliferation
of
wearable
healthcare
devices
has
marked
a
revolutionary
shift
in
personal
health
monitoring
and
management
paradigm.
These
devices,
ranging
from
fitness
trackers
to
advanced
biosensors,
have
not
only
made
more
accessible,
but
also
transformed
way
individuals
engage
with
their
data.
By
continuously
signs,
physical-based
biochemical-based
such
as
heart
rate
blood
glucose
levels,
technology
offers
insights
into
human
health,
enabling
proactive
rather
than
reactive
approach
healthcare.
This
towards
personalized
empowers
knowledge
tools
make
informed
decisions
about
lifestyle
medical
care,
potentially
leading
earlier
detection
issues
tailored
treatment
plans.
review
presents
fabrication
methods
flexible
applications
care.
The
potential
challenges
future
prospectives
are
discussed.
Язык: Английский
Oral and Gingival Crevicular Fluid Biomarkers for Jawbone Turnover Diseases: A Scoping Review
Diagnostics,
Год журнала:
2024,
Номер
14(19), С. 2184 - 2184
Опубликована: Сен. 30, 2024
Gingival
crevicular
fluid
(GCF)
and
oral
have
emerged
as
promising
diagnostic
tools
for
detecting
biomarkers.
This
review
aimed
to
evaluate
the
existing
literature
on
using
fluids
a
source
of
biomarkers
bone
turnover
diseases
affecting
jawbone.
A
comprehensive
search
strategy
was
executed
between
August
2014
2024
across
five
major
databases
(Web
Science,
EBSCOhost
Dentistry
&
Oral
Sciences
Source,
Cochrane
Library,
Scopus,
PubMed)
grey
sources.
The
Preferred
Reporting
Items
Systematic
Reviews
Meta-Analyses
extension
Scoping
(PRISMA-ScR)
applied.
screening
facilitated
Rayyan
at
rayyan.ai
Endnote
X20
software
tools,
culminating
in
evaluation
14,965
citations
from
34
literature.
Following
rigorous
scrutiny,
37
articles
were
selected
inclusion
this
review,
encompassing
such
periodontitis,
medication-related
osteonecrosis
jaw
(MRONJ),
osteoporosis.
quality
included
observational
studies
assessed
Revised
Risk
Bias
Assessment
Tool
Non-Randomized
Studies
(RoBANS
2).
Interleukin-1
beta
(IL-1β),
sclerostin,
osteoprotegerin
(OPG),
interleukin-34
(IL-34)
significant
GCF,
they
mainly
periodontitis
Osteocalcin
(OC),
IL-1β,
tumor
necrosis
factor-alpha
(TNF-α),
interleukin-6
(IL-6),
OPG,
matrix
metalloproteinase-9
(MMP-9)
or
saliva,
MRONJ,
These
findings
underscore
potential
use
fluids,
which
are
regarded
non-invasive
biomarker
identification
turnover.
Many
overlap,
it
is
important
identify
other
specific
enable
accurate
diagnosis
these
conditions.
Язык: Английский
Biomarkers in Saliva to Assess the State of Periodontal Disease
IntechOpen eBooks,
Год журнала:
2025,
Номер
unknown
Опубликована: Май 22, 2025
Periodontal
disease
is
a
multifactorial
infectious
and
immunoinflammatory
condition
that
affects
the
tissues
surrounding
teeth,
potentially
leading
to
irreversible
damage
tooth
loss.
Early
detection
diagnosis
are
crucial
preventing
its
progression
associated
systemic
health
risks.
Traditional
clinical
diagnostic
methods,
such
as
probing
depth
radiographic
assessments,
have
limitations
in
detecting
early-stage
disease.
Consequently,
molecular
biomarkers
found
saliva
emerged
promising
tools
for
early
monitoring
of
periodontal
These
include
inflammatory
mediators,
enzymes,
bone
remodeling
markers,
microbial
metabolites,
providing
valuable
insights
into
status
progression.
Advances
omics
technologies,
including
proteomics
genomics,
further
enhanced
identification
potential
biomarkers,
paving
way
precision
medicine
periodontology.
This
chapter
reviews
role
specific
salivary
assessment,
highlighting
their
potential,
applications,
future
research
directions
field.
Язык: Английский
Association between Periodontal Disease and Obesity: Umbrella Review
Medicina,
Год журнала:
2024,
Номер
60(4), С. 621 - 621
Опубликована: Апрель 11, 2024
Objective:
Determine
the
association
between
periodontal
disease
(PD)
and
obesity
through
an
umbrella
review.
Materials
Methods:
A
search
for
information
until
March
2024
was
carried
out
in
following
electronic
databases:
PubMed,
Cochrane
library,
Scopus,
SciELO,
Web
of
Science,
Google
Scholar,
Proquest
Dissertations
Theses,
OpenGrey.
We
included
studies
that
were
systematic
reviews
(SR)
with
or
without
meta-analysis,
time
language
restrictions,
evaluated
primary
associated
PD
obesity.
Literary
narrative
reviews,
rapid
intervention
studies,
observational
preclinical
basic
research,
summaries,
comments,
case
reports,
protocols,
personal
opinions,
letters,
posters
excluded.
The
AMSTAR-2
tool
used
to
determine
quality
overall
confidence
studies.
Results:
preliminary
yielded
a
total
419
articles,
discarding
those
did
not
meet
selection
criteria,
leaving
only
14
articles.
All
reported
obesity,
OR
RR
ranging
from
1.1
1.46
1.64
2.21,
respectively.
Conclusions:
Based
on
results
conclusions
SR
high
level,
is
Язык: Английский
Alterations in salivary biomarkers in relation to periodontal health and obesity among Hong Kong adolescents
Journal of Dentistry,
Год журнала:
2024,
Номер
146, С. 105055 - 105055
Опубликована: Май 10, 2024
:
To
explore
the
association
among
salivary
biomarkers,
periodontal
inflammation,
and
adiposity
status
in
adolescents.
This
study
included
180
Hong
Kong
adolescents
aged
12–15
years.
Anthropometric
measurements
including
central
obesity
surrogate,
waist-to-height
ratio
(WHtR),
dental
examinations
were
conducted.
The
participants
classified
into
four
groups
as
follows:
with
normal
WHtR
less
extensive
inflammation
(NW+LP);
high
(HW+LP);
more
(NW+P);
(HW+P).
Saliva
collected
to
measure
physicochemical
parameters,
total
bacterial
load,
levels
of
protein
biomarkers
secretory
phospholipase
A2
group
IIA
(sPLA2-IIA)
interleukin-6
(IL-6).
Data
analysed
by
Kruskal-Wallis
test
Spearman
correlation
coefficient.
Salivary
IL-6
sPLA2-IIA
output
differed
significantly
between
(P
=
0.041,
0.027,
0.043,
respectively).
NW+P
had
higher
than
NW+LP
0.034)
lower
HW+LP
0.038).
negatively
correlated
number
sextants
healthy
gingivae
positively
WHtR.
load
associated
extent
but
not
those
Adolescents
different
may
have
mechanisms
inflammation.
Investigating
health
holds
potential
benefits
identifying
individuals
at
risk
customizing
oral
promotion
strategies
for
varying
adiposity,
even
early
adolescence.
Язык: Английский
Inflammatory profile of patients with different weight diagnoses and similar periodontal condition: A systematic review
Journal of Indian Society of Periodontology,
Год журнала:
2024,
Номер
28(1), С. 32 - 42
Опубликована: Янв. 1, 2024
Abstract:
Background:
This
study
aimed
to
systematically
review
the
literature
regarding
inflammatory
profiles,
measured
by
cytokines
and
chemokines,
of
individuals
with
different
diagnoses
weight,
but
similar
periodontal
condition.
Materials
Methods:
Searches
were
performed
in
five
databases
(Scopus,
EMBASE,
PubMed,
Web
Science,
Cochrane-Central).
Studies
that
compared
profile
normal-weight
those
obesity
evaluated
same
cytokine,
collection
method,
diagnosis
(periodontal
health,
gingivitis,
or
periodontitis)
included.
Cross-sectional
studies
underwent
evaluation
independent
researchers
using
Joanna
Briggs
Institute
Critical
Appraisal
Checklist.
The
GRADE
(Grades
Recommendation,
Assessment,
Development
Evaluation)
system
assessed
evidence
certainty.
Results:
Twelve
was
done
on
basis
body
mass
index,
waist
circumference,
waist–hip
ratio.
Pro-inflammatory
(interleukin-6
[IL-6],
tumor
necrosis
factor-α
[TNF]-α,
IL-1β,
IL-31,
IL-34)
analyzed
serum,
saliva,
gingival
crevicular
fluid
(GCF),
plasma.
Periodontal
varied
across
studies.
TNF-α
expression
significantly
higher
health
periodontitis.
Serum
IL-1β
levels
showed
mixed
results,
salivary
elevated
obese
individuals.
IL-6
individuals,
regardless
status.
IL-34
IL-10
no
significant
differences
groups.
Monocyte
chemoattractant
protein-4
(MCP-4)
periodontitis
health.
IL-31
GCF
between
nonobese
without
Conclusions:
Heterogeneous
results
noted
for
IL-6,
IL-34,
TNF-α,
MCP-4,
hindering
conclusions
weight’s
impact
profiles
patients.
Язык: Английский