Journal of Cardiovascular Intervention, Год журнала: 2024, Номер 3(3), С. 136 - 136
Опубликована: Янв. 1, 2024
Язык: Английский
Surfaces and Interfaces, Год журнала: 2025, Номер unknown, С. 105735 - 105735
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
2
Ceramics International, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
2
International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(4), С. 1710 - 1710
Опубликована: Фев. 17, 2025
Nose-to-brain (N2B) drug delivery is a promising technique for the treatment of brain diseases. It allows to enter without passing through blood-brain barrier. However, nasal cavity and mucosa can restrict amount absorbed. Recent studies non-thermal plasma (NTP) have shown improvement in vitro cells tissues. whether NTP treatments enhance vivo drugs neurodegenerative disease like Alzheimer's (AD) into via N2B remains unclear. The used this study was galantamine hydrobromide. Galantamine treat patients with mild moderate AD. Based on principle NTP, type dielectric barrier discharge (DBD) plasma, which we called spiral DBD microplasma, designed. inserted nose rat depth 2 mm. microplasma driven by sinusoidal voltage 4 min, followed immediate administration galantamine. effect distribution evaluated using matrix-assisted laser desorption/ionization-imaging mass spectrometry (MALDI-IMS). results showed high left right hemispheres treated compared control discharge. novel contribution designs. In addition, has also created approach potential becoming non-invasive method enhancing neurological disorders.
Язык: Английский
Процитировано
1
Polymers, Год журнала: 2024, Номер 16(13), С. 1878 - 1878
Опубликована: Июль 1, 2024
Heart problems are quite prevalent worldwide. Cardiomyocytes and stem cells two examples of the supporting matrix that used in integrated process cardiac tissue regeneration. The objective is to create innovative materials can effectively replace or repair damaged muscle. One most effective appealing 3D/4D scaffolds for creating an appropriate milieu growth healing hydrogel. In order successfully regenerate heart tissue, bioactive biocompatible hydrogels required preserve infarcted region bid support restoration myocardial wall stress, cell survival function. engineering uses a variety hydrogels, such as natural synthetic polymeric hydrogels. This article provides quick overview various hydrogel types employed engineering. Their benefits drawbacks discussed. Hydrogel-based techniques regeneration also addressed, along with their clinical application future
Язык: Английский
Процитировано
7
Journal of Condensed Matter, Год журнала: 2025, Номер 3(02), С. 9 - 16
Опубликована: Май 4, 2025
Orthopaedic biomaterials play a pivotal role in advancing fracture fixation, joint replacement, and dynamic stabilization within orthopaedic applications. Primarily composed of metals, these exhibit outstanding properties including high strength, ductility, toughness, hardness, corrosion resistance, durability, biocompatibility. Despite their versatility, the landscape implant materials remains dominated by limited range ceramics, composites polymers. However, durability implants is challenged biological reactions material degradation caused wear electrochemical corrosion. This article examines developments that have taken place with respect to applications surgery. encompasses history, types polymers, composite biomaterials, processes fabricating them. The characteristics like biocompatibility, mechanical properties, fluid stability, ability induce osseointegration relevance such for surgery also discussed this article. Special attention given development novel bioactive metallic means improving resistance biocompatibility changing surface applying coats. scope review further covers advanced technologies smart bio-materials, 3D/4D printing, use nanotechnology, prosthetics. Further, discusses current status future trends concerning greater detail.
Язык: Английский
Процитировано
0
Applied Surface Science, Год журнала: 2024, Номер 669, С. 160521 - 160521
Опубликована: Июнь 12, 2024
Язык: Английский
Процитировано
2
Molecules, Год журнала: 2024, Номер 29(20), С. 4927 - 4927
Опубликована: Окт. 18, 2024
An extracellular matrix protein, fibronectin (Fn), was covalently immobilized on 316L stainless steel, L605 cobalt chromium (CoCr), and nickel titanium (NiTi) surfaces through an 11-mercaptoundecanoic acid (MUA) self-assembled monolayer (SAM) pre-formed these surfaces. Polarization modulation infrared reflection adsorption spectroscopy (PM-IRRAS) confirmed the presence of Fn The attached to SAM found be stable under fluid shear stress. Deconvolution amide I band indicated that secondary structure changes significantly upon immobilization SAM-functionalized metal substrate. Scanning electron microscopy energy dispersive X-ray analysis revealed spacing between molecules a modified commercial stent surface is approximately 66 nm, which has been reported most appropriate for cell/surface interactions.
Язык: Английский
Процитировано
1
Journal of Cardiovascular Intervention, Год журнала: 2024, Номер 3(3), С. 136 - 136
Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
0