Опубликована: Янв. 1, 2024
Язык: Английский
Опубликована: Янв. 1, 2024
Язык: Английский
Опубликована: Март 26, 2025
Folic acid (FA) residue is a well-known and widely spread targeting ligand, or biovector, used as component in engineering artificial nanosized submicron particles (NSPs) to target various cells treat variety of diseases that are associated with FA (or folate) receptors (FR) overexpression. A particular place the list these held by cancer types, for which overexpression FR on cell surface often accompanied more severe disease course, increased resistance conventional chemotherapy, poorer prognosis. The incorporation albumin into NSPs has been shown enhance their biocompatibility, give high compatibility drug molecules, prolong circulation, reduce thrombogenic activity, improve colloidal stability. Nowadays albumin-based agent photothermal photodynamic therapy, combined visualization, theranostics (also known theragnostics) types cancer: breast, cervical, ovarian, prostate, nasopharyngeal, gastric, colorectal, liver cancer, brain tumors. limited number studies have also focused use rheumatoid arthritis treatment. In this review, we discuss ways FA-albumin conjugation albumin-modified systems. An application delivery systems base serum therapy diagnostics discussed.
Язык: Английский
Процитировано
0Coordination Chemistry Reviews, Год журнала: 2025, Номер 535, С. 216641 - 216641
Опубликована: Март 30, 2025
Язык: Английский
Процитировано
0Опубликована: Янв. 1, 2025
Язык: Английский
Процитировано
0Carbohydrate Polymers, Год журнала: 2024, Номер 348, С. 122797 - 122797
Опубликована: Сен. 26, 2024
Язык: Английский
Процитировано
1Опубликована: Янв. 1, 2024
Язык: Английский
Процитировано
0