Impact of Neutrophil-to-Lymphocyte Ratio on Stroke Severity and Clinical Outcome in Anterior Circulation Large Vessel Occlusion Stroke DOI Creative Commons
Zülfikar Memiş, Erdem Gürkaş, Atilla Özcan Özdemir

и другие.

Diagnostics, Год журнала: 2024, Номер 14(24), С. 2880 - 2880

Опубликована: Дек. 21, 2024

Background: The prognostic value of the neutrophil–lymphocyte ratio (NLR) in ischemic stroke remains debated due to cohort variability and treatment heterogeneity across studies. This study evaluates relationship between admission NLR, severity 90-day outcomes patients with anterior circulation large vessel occlusion (LVO) undergoing early, successful revascularization. Methods: A retrospective multicenter was conducted 1082 treated mechanical thrombectomy for acute stroke. baseline National Institutes Health Stroke Scale (NIHSS), 24 h NIHSS modified Rankin (mRS) analyzed using logistic regression. Results: Admission NLR correlated weakly but significantly both (p = 0.018) 0.005) scores, reflecting severity. However, multivariate analysis showed that higher scores (OR 0.831, p 0.000) prolonged puncture-to-recanalization times 0.981, were independent predictors poor outcomes, whereas not 0.557). Conclusions: is associated does independently predict clinical at 90 days achieving early These findings underscore critical role inflammation phase suggest its long-term limited this context.

Язык: Английский

Impact of Neutrophil-to-Lymphocyte Ratio on Stroke Severity and Clinical Outcome in Anterior Circulation Large Vessel Occlusion Stroke DOI Creative Commons
Zülfikar Memiş, Erdem Gürkaş, Atilla Özcan Özdemir

и другие.

Diagnostics, Год журнала: 2024, Номер 14(24), С. 2880 - 2880

Опубликована: Дек. 21, 2024

Background: The prognostic value of the neutrophil–lymphocyte ratio (NLR) in ischemic stroke remains debated due to cohort variability and treatment heterogeneity across studies. This study evaluates relationship between admission NLR, severity 90-day outcomes patients with anterior circulation large vessel occlusion (LVO) undergoing early, successful revascularization. Methods: A retrospective multicenter was conducted 1082 treated mechanical thrombectomy for acute stroke. baseline National Institutes Health Stroke Scale (NIHSS), 24 h NIHSS modified Rankin (mRS) analyzed using logistic regression. Results: Admission NLR correlated weakly but significantly both (p = 0.018) 0.005) scores, reflecting severity. However, multivariate analysis showed that higher scores (OR 0.831, p 0.000) prolonged puncture-to-recanalization times 0.981, were independent predictors poor outcomes, whereas not 0.557). Conclusions: is associated does independently predict clinical at 90 days achieving early These findings underscore critical role inflammation phase suggest its long-term limited this context.

Язык: Английский

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