International Dairy Journal, Год журнала: 2025, Номер unknown, С. 106250 - 106250
Опубликована: Март 1, 2025
Язык: Английский
Analytical Methods, Год журнала: 2025, Номер unknown
Опубликована: Янв. 1, 2025
A sustainable and comprehensive process for extracting triterpenoids from persimmon leaves was developed the first time. This method utilizes deep eutectic solvents extraction macroporous resins recovery of triterpenoids.
Язык: Английский
Процитировано
1
European Journal of Medicinal Chemistry, Год журнала: 2025, Номер 287, С. 117350 - 117350
Опубликована: Фев. 6, 2025
Язык: Английский
Процитировано
0
Processes, Год журнала: 2025, Номер 13(3), С. 904 - 904
Опубликована: Март 19, 2025
In this study, we thoroughly investigated the stability of haloperidol using a comprehensive set chromatographic and thermal analyses. Various stress conditions were examined, including exposure to oxidizing agents (such as hydrogen peroxide), dry heat, photolytic conditions, acid alkaline hydrolysis. Significant degradation was observed in acidic environments, leading formation by-products, specifically DPA, DPB, DPC, DPD for basic conditions. contrast, demonstrated robust under photolytic, oxidative, dry-heat For analysis drug its products, C-18 column employed, coupled with mobile phase consisting methanol phosphate buffer (pH = 9.8) 90:10 (v/v) ratio. The analytical method rigorously validated according ICH Q2 (R1) guidelines, ensuring accuracy reliability. This exhibited excellent linearity within concentration range 1 50 µg/mL, an R2 0.999. Additionally, is applicable commercial formulations, without need prior extraction. LC-MS/MS revealed distinct m/z values fragmentation spectra corresponding impurity not documented European Pharmacopoeia monograph drug. Three additional products identified based on base fragments. Thermal analyses, thermogravimetric (TGA), differential scanning calorimetry (DSC), (DTA), provided further evidence active ingredient’s stability, melting temperature approximately 150 °C. These results collectively offer valuable insights into behavior haloperidol, providing critical implications pharmaceutical quality integrity various environmental
Язык: Английский
Процитировано
0
Functional & Integrative Genomics, Год журнала: 2025, Номер 25(1)
Опубликована: Фев. 15, 2025
Язык: Английский
Процитировано
0
The European Physical Journal Plus, Год журнала: 2025, Номер 140(2)
Опубликована: Фев. 24, 2025
Язык: Английский
Процитировано
0
ChemistrySelect, Год журнала: 2025, Номер 10(8)
Опубликована: Фев. 1, 2025
Abstract Sustainable nanotechnology is becoming more prominent daily, especially in preparing magnetic nanoparticles like CuFe 2 O 4 . This work involves the phyto‐mechanochemical (mechanical and green) synthesis of NPs by Spinacia oleracea leaf extract. Various spectroscopic analytical techniques including FTIR, UV–vis, XRD, SEM, VSM, EDX, BET, confirmed formation characterizations CuFe₂O₄ with 26 nm diameter. Results from VSM analysis demonstrated ferromagnetism high saturation magnetization. At same time UV–vis spectroscopy showed optical characteristics these materials. The photocatalytic properties were tested through decoloration textile industry pollutant congo red (CR) dye. an effective degradation rate 89% for CR dye during a 90 min incubation period under their best operating conditions. mechanism was studied kinetic measurements utilizing first‐order Langmuir‐Hinshelwood models. nanoparticle size bioactive enabled them to demonstrate powerful antibacterial capabilities against Streptococcus Escherichia coli bacteria. Uniformity key feature phyto‐mechanically synthesized while demonstrating potential environmental remediation biomedical research.
Язык: Английский
Процитировано
0
Industrial Crops and Products, Год журнала: 2025, Номер 227, С. 120796 - 120796
Опубликована: Март 6, 2025
Язык: Английский
Процитировано
0
Chemical Papers, Год журнала: 2025, Номер unknown
Опубликована: Март 14, 2025
Язык: Английский
Процитировано
0
International Journal of Molecular Sciences, Год журнала: 2025, Номер 26(6), С. 2678 - 2678
Опубликована: Март 16, 2025
Despite the substantial advances in cancer therapies, developing safe and effective treatment methodologies is critical. Natural (plant-derived compounds), such as flavonoids, might be crucial a methodology without toxicity toward healthy tissues. Prunin flavonoid with potential to used biomedical applications. has yet undergo thorough scientific research, its precise molecular mechanisms of action remain largely unexplored. This review summarizes therapeutic prunin for first time, focusing on underlying an anticancer compound. gained significant attention due antioxidant, anti-inflammatory, effects. aims unlock how functions at level exert effects, primarily modulating key cellular pathways. Furthermore, we have discussed prunin’s adjunctive therapy conventional treatments, highlighting ability strengthen responses while decreasing drug resistance. Moreover, discussion probes into innovative delivery methods, particularly nanoformulations, that address bioavailability, solubility, stability limitations optimize application. By providing comprehensive analysis properties, this stimulate further exploration using agent, thereby progressing development targeted, selective, safe, methods.
Язык: Английский
Процитировано
0
Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Год журнала: 2025, Номер unknown, С. 126086 - 126086
Опубликована: Март 1, 2025
Язык: Английский
Процитировано
0