Revolutionizing Prostate Cancer Therapy: Artificial intelligence – based Nanocarriers for Precision Diagnosis and Treatment

Critical Reviews in Oncology/Hematology, Год журнала: 2025, Номер unknown, С. 104653 - 104653

Опубликована: Фев. 1, 2025

Язык: Английский

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Utilizing Gold Nanoparticles in Plasmonic Photothermal Therapy for Cancer Treatment

Heliyon, Год журнала: 2025, Номер 11(4), С. e42738 - e42738

Опубликована: Фев. 1, 2025

In recent decades, significant attention has been directed towards gold nanoparticles due to their exceptional properties, capturing the interest of researchers globally. Their unique characteristics, such as localized surface plasmon resonance, high area volume ratio, biocompatibility, and facile functionalization, render them highly suitable for diverse applications, ranging from optoelectronics sensing surface-enhanced spectroscopies biomedical uses, particularly in realm photothermal therapy. Plasmonic therapy, an emerging technology, garnered substantial its potential cancer treatment management. This approach employs agents, nanoparticles, which absorb light near-infrared region. When these agents accumulate within cells, absorbed photon energy is converted into heat, inducing local hyperthermia. effect selectively eliminates damaged cells adjacent while sparing normal cells. Various shapes sizes have proven well-suited candidates paper provides overview distinctive properties nanoparticles. It delves functionalization techniques crucial ensuring cells' effective retention targeting this context, present reviews applications with different plasmonic encompassing nanospheres, nanorods, nanoshells, nanostars, nanocages.

Язык: Английский

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Advances in Materials Science for Precision Melanoma Therapy: Nanotechnology-Enhanced Drug Delivery Systems

Pharmaceutics, Год журнала: 2025, Номер 17(3), С. 296 - 296

Опубликована: Фев. 24, 2025

Melanoma, a highly aggressive form of skin cancer, poses major therapeutic challenge due to its metastatic potential, resistance conventional therapies, and the complexity tumor microenvironment (TME). Materials science nanotechnology advances have led using nanocarriers such as liposomes, dendrimers, polymeric nanoparticles, metallic nanoparticles transformative solutions for precision melanoma therapy. This review summarizes findings from Web Science, PubMed, EMBASE, Scopus, Google Scholar highlights role in overcoming treatment barriers. Nanoparticles facilitate passive active targeting through mechanisms enhanced permeability retention (EPR) effect functionalization with tumor-specific ligands, thereby improving accuracy drug delivery reducing systemic toxicity. Stimuli-responsive systems multi-stage further improve overcome challenges poor penetration resistance. Emerging platforms combine diagnostic imaging delivery, paving way personalized medicine. However, there are still issues scalability, biocompatibility, regulatory compliance. comprehensive potential integrating genetics proteomics, scalable, patient-specific therapies. These interdisciplinary innovations promise redefine provide safer, more effective, accessible treatments. Continued research is essential bridge gap between evidence-based scientific clinical applications.

Язык: Английский

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Nanomedicine for cancer patient‐centered care

MedComm, Год журнала: 2024, Номер 5(11)

Опубликована: Окт. 20, 2024

Abstract Cancer is a leading cause of morbidity and mortality worldwide, an increase in incidence estimated the next future, due to population aging, which requires development highly tolerable low‐toxicity cancer treatment strategies. The use nanotechnology tailor treatments according genetic immunophenotypic characteristics patient's tumor, allow its targeted release, can meet this need, improving efficacy minimizing side effects. Nanomedicine‐based approach for diagnosis rapidly evolving field. Several nanoformulations are currently clinical trials, some have been approved marketed. However, their large‐scale production still hindered by in‐depth debate involving ethics, intellectual property, safety health concerns, technical issues, costs. Here, we survey key approaches, with specific reference organ‐on chip technology, cutting‐edge tools, such as CRISPR/Cas9 genome editing, through nanosystems needs personalized diagnostics therapy patients. An update provided on nanopharmaceuticals marketed those undergoing trials. Finally, discuss emerging avenues field challenges be overcome transfer nano‐based precision oncology into daily life.

Язык: Английский

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Phytoreduced gold nanoparticles from vitalmelon promote white adipocyte browning in murine cells by targeting phospholipase D2

Journal of Photochemistry and Photobiology, Год журнала: 2024, Номер 25, С. 100254 - 100254

Опубликована: Дек. 10, 2024

Язык: Английский

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