Global burden of atrial fibrillation/atrial flutter and its attributable risk factors from 1990 to 2021
EP Europace,
Год журнала:
2024,
Номер
26(7)
Опубликована: Июль 1, 2024
Abstract
Aims
To
devise
effective
preventive
measures,
a
profound
understanding
of
the
evolving
patterns
and
trends
in
atrial
fibrillation
(AF)
flutter
(AFL)
burdens
is
pivotal.
Our
study
was
designed
to
quantify
burden
delineate
risk
factors
associated
with
AF
AFL
across
204
countries
territories
spanning
1990–2021.
Methods
results
Data
pertaining
were
sourced
from
Global
Burden
Disease
Study
2021.
The
AF/AFL
evaluated
using
metrics
such
as
incidence,
disability-adjusted
life
years
(DALYs),
deaths,
their
corresponding
age-standardized
rates
(ASRs),
stratified
by
age,
sex,
socio-demographic
index
(SDI),
human
development
(HDI).
estimated
annual
percentage
change
employed
changes
ASRs.
Population
attributable
fractions
calculated
determine
proportional
contributions
major
deaths.
This
analysis
encompassed
period
1990
Globally,
2021,
there
4.48
million
incident
cases
[95%
uncertainty
interval
(UI):
3.61–5.70],
8.36
DALYs
(95%
UI:
6.97–10.13)
0.34
deaths
0.29–0.37)
attributed
AF/AFL.
well
its
displayed
substantial
variations
based
on
gender,
SDI
quintiles,
geographical
regions.
High
systolic
blood
pressure
emerged
leading
contributor
prevalence,
death,
DALY
rate
globally
among
all
potential
factors,
followed
closely
high
body
mass
index.
Conclusion
underscores
enduring
significance
prominent
public
health
concern
worldwide,
marked
regional
national
variations.
Despite
for
prevention
management
AF/AFL,
pressing
imperative
adopt
more
cost-effective
strategies
interventions
target
modifiable
particularly
areas
where
or
escalating.
Язык: Английский
Global trends and epidemiological impact of metabolic risk factors on atrial fibrillation and atrial flutter from 1990 to 2021
Scientific Reports,
Год журнала:
2025,
Номер
15(1)
Опубликована: Фев. 7, 2025
Abstract
Atrial
fibrillation
(AF)
and
atrial
flutter
(AFL)
are
cardiac
arrhythmias
associated
with
high
morbidity
mortality.
This
cross-sectional
observational
study
assesses
the
epidemiological
burden
of
AF/AFL
concerning
metabolic
risk
factors
using
Global
Burden
Disease
(GBD)
2021
database.
Age-standardized
disability-adjusted
life
years
rate
(ASDR),
mortality,
estimated
annual
percentage
change
were
calculated.
The
Bayesian
Age-Period-Cohort
model
was
utilized
to
predict
future
trends
in
ASDR
age-standardized
mortality
(ASMR)
for
2030.
Between
1990
2021,
rose
from
34.22
34.94,
whereas
ASMR
increased
1.46
1.50
per
100,000
people.
High/high–middle
Socio-Demographic
Index
(SDI)
regions
showed
decreasing
ASMR,
low
middle
SDI
increasing
trends.
In
highest
recorded
Australasia,
North
America,
Western
Europe,
significant
country-level
variability.
Projections
indicate
a
declining
trend
stable
through
global
rise
attributable
necessitates
comprehensive
region-specific
public
health
strategies.
Further
research
is
warranted
develop
implement
effective
measures
mitigate
these
conditions
improve
cardiovascular
outcomes
worldwide.
Язык: Английский
Heart rate variability in patients with atrial fibrillation of sinus rhythm or atrial fibrillation: chaos or merit?
Annals of Medicine,
Год журнала:
2025,
Номер
57(1)
Опубликована: Март 13, 2025
Atrial
fibrillation
(AF)
is
the
most
common
sustained
cardiac
arrhythmia
characterized
by
consistently
irregular
atrial
and
ventricular
contractions.
Heart
rate
variability
(HRV)
refers
to
changes
in
intervals
between
consecutive
heartbeats.
In
sinus
rhythm,
HRV
may
be
subtle
quantitatively
reflecting
dynamic
interplay
of
autonomic
nervous
system,
which
plays
a
crucial
role
onset,
development,
maintenance
AF.
metrics,
consisting
time-domain,
frequency-domain,
nonlinear
parameters,
have
been
verified
vary
significantly
before
after
AF
episodes,
treatment-related
procedures
such
as
electrical
cardioversion,
ablation,
surgery
Therefore,
serve
digital
biomarker
predicting
risk
long-term
acute
period,
identification
patients
with
rhythm
recurrence
stratification
procedures.
predominantly
influenced
atrioventricular
node
conduction
under
onslaught
impulses,
shows
huge
disparity
compared
that
rhythm.
Despite
this,
still
provides
valuable
prognostic
information,
reduced
indicate
poor
heart
function
outcomes
being
lots
variables,
can
an
independent
clinical
management
throughout
its
entire
lifecycle.
Язык: Английский
COVID-associated left atrial changes as a significant predictor of atrial fibrillation recurrence
Russian Journal of Cardiology,
Год журнала:
2025,
Номер
30(2), С. 5801 - 5801
Опубликована: Март 14, 2025
Aim.
To
determine
the
prognostic
significance
of
left
atrial
(LA)
changes
after
SARS-CoV-2
infection
on
fibrillation
recurrence
rate
catheter
ablation.
Material
and
methods
.
The
study
involved
40
patients.
All
patients
were
monitored
3,
6
12
months,
as
well
when
clinical
performance
disease
changed.
average
follow-up
time
was
19±3
months.
Recurrence
observed
in
18
(45%).
Results
groups
completely
comparable
age
(p=0,382),
sex
(p=0,604),
arrhythmia
type
(p=0,842),
history
previous
surgeries
(p=0,949).
Arrhythmia
9,33
[2,18;
39,96]
times
more
common
who
had
before
surgery
(p=0,01).
ablation
caused
by
posterior
wall
fibrosis
without
pulmonary
vein
reconnection
is
an
independent
risk
factor
for
another
attempt
(p=0,020).
Also,
9
[2,09;
38,79]
atrium
box
isolation
(p=0,002).
About
half
area
with
represented
myocardium
amplitude
less
than
0,25
mV.
In
recurrence,
this
15,9%
smaller
(49±18,4%
33,1±17,5%,
respectively;
p=0,020).
Differences
myocardial
0,5
mV
are
pronounced
21,4%
(p=0,006).
LA
tissue
normal
signal
(>0,75
mV)
only
17,4%
which
2,14
remission
(p=0,011).
Conclusion
stable
over
significantly
increase
Additional
does
not
reduce
affect
duration
sinus
rhythm
control.
Язык: Английский
Low blood flow velocity in the left atrial appendage in sinus rhythm as a predictor of atrial fibrillation: results of a prospective cohort study with 3 years of follow-up
G Klinger,
Lea Schettler,
G Schettler
и другие.
Neurological Research and Practice,
Год журнала:
2025,
Номер
7(1)
Опубликована: Апрель 13, 2025
Atrial
fibrillation
(AF)
is
a
common
cause
of
cardioembolic
stroke
and
can
lead
to
severe
recurrent
cerebrovascular
events.
Thus,
identifying
patients
suffering
from
events
caused
by
undetected
AF
crucial.
Previously,
we
found
an
association
between
increasing
severity
decreasing
left
atrial
appendage
(LAA)
blood
flow
velocity
below
60
cm/s.
This
was
prospective
single-center
cohort
study
including
hospitalized
who
underwent
transesophageal
echocardiography
(TEE)
in
sinus
rhythm.
The
participants
were
divided
into
two
groups
(≥
cm/s;<60
cm/s)
based
on
their
maximum
LAA
velocity.
results
the
cardiovascular
risk
assessment
24-
72-hour
ECG
Holter
recorded.
Follow-up
appointments
scheduled
at
3,
6,
12,
24
36
months.
primary
endpoint
new-onset
AF.
statistics
included
Cox-proportional-hazard-model
binary
logistic
regression.
Numerical
data
or
categorical
analyzed
with
Mann-Whitney
U
test
chi-square
test.
A
total
166
recruited.
median
64
New-onset
diagnosed
22.9%
patients.
An
≤
cm/s
associated
threefold
increased
(35.8%
vs.
11.5%;
HR3.56;
CI95%1.70-7.46;
p
<
0.001),
independently
according
multivariate
analysis
(p
=
0.035).
Furthermore,
(OR1.043;
CI95%1.021-1.069;
0.001).
low
(≤
rhythm
prospectively
Additional
simple
LAA-TEE
examinations
could
help
identify
benefit
more
accurate
cardiac
monitoring.
Язык: Английский
The Involvement and Manifestations of SARS-CoV-2 Virus in Cardiovascular Pathology
Sofia Teodora Hărșan,
Anca Sin
Medicina,
Год журнала:
2025,
Номер
61(5), С. 773 - 773
Опубликована: Апрель 22, 2025
Although
the
acute
phase
of
COVID-19
pandemic
has
subsided,
emergence
post-COVID-19
condition
presents
a
new
and
complex
public
health
challenge,
characterized
by
persistent,
multisystem
symptoms
that
can
endure
for
weeks
or
months
after
initial
infection
with
SARS-CoV-2
virus,
significantly
affecting
survivors’
quality
life.
Among
most
concerning
sequelae
are
cardiovascular
complications,
which
encompass
broad
spectrum
conditions,
including
arrhythmias,
myocardial
damage,
postural
orthostatic
tachycardia
syndrome.
This
narrative
review
explores
burden
on
reviewing
latest
relevant
findings
in
literature
highlighting
different
aspects
COVID-19’s
involvement.
investigates
pathophysiological
mechanisms
underlying
involvement
condition,
focus
direct
viral
invasion
via
ACE2
receptors,
immune-mediated
injury,
cytokine
storm,
systemic
inflammation,
endothelial
dysfunction,
mitochondrial
injury.
The
interplay
between
pre-existing
diseases,
such
as
hypertension,
atherosclerosis,
diabetes,
atrial
fibrillation,
is
also
explored,
revealing
individuals
conditions
at
heightened
risk
both
severe
illness
long-term
complications.
Long-term
immune
activation
persistence
antigens
increasingly
recognized
contributors
to
ongoing
even
mild
asymptomatic
infections.
As
healthcare
system
continues
adapt
consequences
pandemic,
deeper
understanding
these
manifestations
essential.
knowledge
will
inform
development
targeted
strategies
prevention,
clinical
management,
rehabilitation
affected
patients.
Furthermore,
insights
gained
from
intersection
be
instrumental
shaping
responses
future
epidemics,
necessity
multidisciplinary
approaches
patient
care
preparedness.
Язык: Английский
Emergence of Atrial Fibrillation and Flutter in COVID-19 Patients: A Retrospective Cohort Study
Healthcare,
Год журнала:
2024,
Номер
12(17), С. 1682 - 1682
Опубликована: Авг. 23, 2024
COVID-19
is
associated
with
various
cardiovascular
complications,
including
arrhythmias.
This
study
investigated
the
incidence
of
new-onset
atrial
fibrillation
(AFB)
and
flutter
(AFL)
in
patients
identified
potential
risk
factors.
We
conducted
a
retrospective
cohort
at
tertiary-care
safety-net
community
hospital
647
diagnosed
from
March
2020
to
2021.
Patients
prior
history
AFB
or
AFL
were
excluded.
Data
on
demographics,
clinical
characteristics,
outcomes
collected
analyzed
using
chi-square
tests,
t-tests,
binary
logistic
regression.
found
that
69
(10.66%)
developed
AFL,
41
(6.34%)
experiencing
The
rates
for
5.4%
0.9%,
respectively.
Older
age
(≥65
years)
was
significantly
AFB/AFL
(OR:
5.43;
95%
CI:
2.31–12.77;
p
<
0.001),
as
development
sepsis
2.73;
1.31–5.70;
=
0.008).
No
significant
association
patient
sex.
Our
findings
indicate
arrhythmias
are
complication
patients,
particularly
among
elderly
those
sepsis.
highlights
need
targeted
monitoring
management
strategies
mitigate
burden
high-risk
populations
during
infection.
Язык: Английский