Enhanced urease inhibitory activity of quercetin via conjugation with silver nanoparticles: synthesis, characterization, and DFT study DOI Creative Commons
Somayeh Asadi, Kobra Rostamizadeh, Hamed Bahrami

и другие.

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Апрель 7, 2025

Urease plays a crucial role in the survival and colonization of Helicobacter pylori (H. pylori). Consequently, urease inhibitors are important managing various diseases associated with H. infection. Given widespread use silver nanoparticles (AgNPs) as antibacterial agents quercetin's known inhibitory properties, we sought to develop potent inhibitor by conjugating quercetin onto AgNPs. In fact, this study aimed enhance activity through its conjugation Quercetin-loaded (Ag@QNPs) were successfully synthesized using Frens method characterized techniques, including UV-Vis spectroscopy, FT-IR XRD analysis, DLS, TEM. The Ag@QNPs was significantly higher (approximately 250 times) than that pure quercetin, demonstrating synergistic effect. contrast, AgNPs alone exhibited minimal against urease. Density functional theory (DFT) calculations revealed favorable interaction energy between surface. These findings suggest potential promising nanomaterials for applications urease-related diseases.

Язык: Английский

Antioxidant and anti-diabetic potential of the green synthesized silver nanoparticles using Martynia annua L. root extract DOI Creative Commons
Megha B. Abbigeri, Bothe Thokchom, Sapam Riches Singh

и другие.

Nano TransMed, Год журнала: 2025, Номер unknown, С. 100070 - 100070

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

4

Investigation of Structural, Optical, Morphological and Compositional Properties of Agglomerated CuMn2O4 Nanoparticles for In Vitro Anticancer Activity Against MCF-7 Cell Lines DOI

M. Priyadharshan,

M. Karthikeyan, S. Rajkumar

и другие.

Journal of Inorganic and Organometallic Polymers and Materials, Год журнала: 2025, Номер unknown

Опубликована: Янв. 13, 2025

Язык: Английский

Процитировано

0

Addressing the silent killer: Nanotechnology for preventing oral bacteria-induced cardiovascular risks DOI
Santosh Mallikarjun Bhavi,

Akshata Choudhari Padti,

Bothe Thokchom

и другие.

Deleted Journal, Год журнала: 2025, Номер 9(1)

Опубликована: Март 4, 2025

Tooth extraction, while essential for oral health, can contribute to systemic complications, particularly increasing cardiovascular risk due bacterial translocation and inflammation. Periodontal disease, a major cause of tooth loss, exacerbates this by serving as reservoir pathogenic bacteria that enter the bloodstream during extractions. This review explores mechanisms linking post-extraction infections diseases evaluates role nanotechnology in mitigating these risks. Advances antimicrobial nanoparticles, nanodrug delivery systems, biosensors offer promising solutions infection control targeted drug delivery. These innovations enhance healing potentially reducing However, challenges remain optimizing material biocompatibility, ensuring clinical efficacy, addressing translational hurdles. underscores need interdisciplinary research integrate into dental practice, ultimately improving both health outcomes.

Язык: Английский

Процитировано

0

A study on the antioxidant, cytotoxicity, and coagulation potential of carbon quantum dots derived from the leaves of Lagerstroemia speciosa DOI Creative Commons
Sapam Riches Singh,

Gouramma R. Kanamadi,

Bothe Thokchom

и другие.

Hybrid Advances, Год журнала: 2025, Номер unknown, С. 100430 - 100430

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

Enhanced urease inhibitory activity of quercetin via conjugation with silver nanoparticles: synthesis, characterization, and DFT study DOI Creative Commons
Somayeh Asadi, Kobra Rostamizadeh, Hamed Bahrami

и другие.

Scientific Reports, Год журнала: 2025, Номер 15(1)

Опубликована: Апрель 7, 2025

Urease plays a crucial role in the survival and colonization of Helicobacter pylori (H. pylori). Consequently, urease inhibitors are important managing various diseases associated with H. infection. Given widespread use silver nanoparticles (AgNPs) as antibacterial agents quercetin's known inhibitory properties, we sought to develop potent inhibitor by conjugating quercetin onto AgNPs. In fact, this study aimed enhance activity through its conjugation Quercetin-loaded (Ag@QNPs) were successfully synthesized using Frens method characterized techniques, including UV-Vis spectroscopy, FT-IR XRD analysis, DLS, TEM. The Ag@QNPs was significantly higher (approximately 250 times) than that pure quercetin, demonstrating synergistic effect. contrast, AgNPs alone exhibited minimal against urease. Density functional theory (DFT) calculations revealed favorable interaction energy between surface. These findings suggest potential promising nanomaterials for applications urease-related diseases.

Язык: Английский

Процитировано

0