Cellulose Chemistry and Technology,
Год журнала:
2024,
Номер
58(9-10), С. 1099 - 1112
Опубликована: Ноя. 25, 2024
Anabasis
articulata
(Chenopodiaceae),
commonly
called
Ajrem,
is
a
medicinal
plant
of
Algerian
flora
arid
and
semi-arid
regions,
extensively
used
in
complementary
medicine
to
treat
diabetes,
eczema,
fever,
kidney
diseases.
The
current
investigation
was
intended
evaluate
the
anti-inflammatory
potential
A.
ethanolic
extract
(EEAA)
its
fractions
that
were
separated
using
decreasing
polarity
solvents
(hexane,
chloroform,
ethyl
acetate,
butanol)
obtain
an
(EEAA),
chloroform
(ChFA),
acetate
(EAFA),
n-butanol
(nBFA),
aqueous
(AqFA).
These
analyzed
LC-MS-MS,
whereas
polyphenols,
flavonoids,
tannins
evaluated
colorimetric
methods.
For
acute
toxicity
study,
one
oral
dose
2
5
g/kg
administered
mice.
vitro
properties
determined
by
egg
albumin
denaturation
test,
vivo
effect
assessed
carrageenan,
croton
oil,
xylene-induced
edema
tests.
these
natural
compounds
silico
via
molecular
docking
simulations
applying
cyclooxygenase
COX2
inhibitory
impact.
Seven
metabolites
identified:
anthrone,
beta-carotene,
butylated
hydroxyanisole,
butylatedhydroxytoluene,
gallic
acid,
myricetin,
rutin.
ChFA
contained
greatest
quantity
polyphenols
flavonoids
(497.98±0.377
mg
GAE/g
79.89±0.789
QE/g).
While
nBFA
showed
highest
amount
total
(162.89±2.103
TAE/g).
evaluation
revealed
all
had
potent
effect.
No
death,
no
toxicological
symptoms,
appreciable
body
weight
changes
between
treated
control
groups
observed.
Oral
administration
EEAA
(200
mg/kg)
significantly
reduced
induced
xylene.
beta
carotene,
rutin
exhibited
most
promising
inhibition
against
COX2.
Significant
effects
demonstrated
vitro,
vivo,
silico.
ariculata
can
be
regarded
as
non-toxic.
findings
are
consistent
with
plant’s
traditional
applications,
which
include
therapy
illnesses.
International Journal of Biological and Chemical Sciences,
Год журнала:
2024,
Номер
18(1), С. 10 - 19
Опубликована: Май 9, 2024
Blighia
sapida
is
widely
used
in
traditional
medicine
for
the
treatment
of
several
diseases
Togo.
This
study
aimed
to
assess
antioxidant
and
anti-inflammatory
properties
sapida.
To
this
end,
a
phytochemical
screening
was
carried
out,
followed
by
an
assessment
DPPH,
total
capacity,
ex
vivo
lipoperoxidation
tests
on
Sprague
Dawley
rats,
evaluation
anti-
inflammatory
activity
egg
albumin
denaturation
test.
The
leaves
extract
scavenged
DPPH
free
radical
with
IC50
172
±
0.577µg/mL
its
capacity
value
40.174
0.638
mg
Eq
AA/g.
In
test
kidney
liver,
showed
significant
inhibitory
effect.
Phytochemical
revealed
presence
tannins,
flavonoids,
alkaloids,
saponosides,
carbohydrate
compounds.
present
results
that
possess
which
may
be
linked
bioactive
compounds
they
contain,
suggesting
their
use
prevent
oxidative
processes.
Pharmacognosy Journal,
Год журнала:
2024,
Номер
16(3), С. 582 - 590
Опубликована: Июль 1, 2024
Introduction:
Uvaria
chamae
and
Sida
linifolia
are
plants
traditionally
used
in
Togo
diabetes
treatment,
an
affection
that
often
leads
to
several
complications.
This
study
aimed
evaluate
the
antihyperglycemic,
anti-inflammatory,
antioxidant
activity
toxicity
of
these
two
extracts.
Methods:
A
phytochemical
analysis
was
carried
out
on
extracts
obtained
either
by
decoction
or
maceration
ethanol
leaves
whole
plant.
Evaluation
antihyperglycemic
consisted
glucose
absorption
test
using
yeast
rats'
muscle
jejunum.
DPPH
test,
total
capacity
assay,
hemolysis
egg
albumin
denaturation
inhibition
assays
evaluation
acute
were
performed.
Results:
Hydroalcoholic
extract
showed
strongest
(p<0.05);
highest
phenolic
contents
(147.93
±
1.01
mg/g),
best
(153.33
4.07),
lowest
IC50
(μg/mL)
for
(296.96
91.69),
a
(825.99
29.24)
(738.10
92.26)
assays.
In
same
way,
hydroalcoholic
linifolia,
(p<0.05),
(71.60
2.16
(146.98
2.81),
(μg/
mL)
(788.28
112.54),
(882.03
20.86)
(1966.18
35.94)
None
rats.
Conclusion:
plant
could
be
candidates
treatment
its
Heliyon,
Год журнала:
2024,
Номер
10(19), С. e38736 - e38736
Опубликована: Сен. 30, 2024
Propolis
produced
by
stingless
bees
contains
various
chemical
compounds
that
contribute
to
its
bioactivity.
The
availability
of
certain
plants
at
the
growth
site
and
propolis's
geographic
origin
have
a
significant
impact
on
composition.
objective
this
study
was
examine
profile,
yield,
total
flavonoid
phenolic
content,
Cellulose Chemistry and Technology,
Год журнала:
2024,
Номер
58(9-10), С. 1099 - 1112
Опубликована: Ноя. 25, 2024
Anabasis
articulata
(Chenopodiaceae),
commonly
called
Ajrem,
is
a
medicinal
plant
of
Algerian
flora
arid
and
semi-arid
regions,
extensively
used
in
complementary
medicine
to
treat
diabetes,
eczema,
fever,
kidney
diseases.
The
current
investigation
was
intended
evaluate
the
anti-inflammatory
potential
A.
ethanolic
extract
(EEAA)
its
fractions
that
were
separated
using
decreasing
polarity
solvents
(hexane,
chloroform,
ethyl
acetate,
butanol)
obtain
an
(EEAA),
chloroform
(ChFA),
acetate
(EAFA),
n-butanol
(nBFA),
aqueous
(AqFA).
These
analyzed
LC-MS-MS,
whereas
polyphenols,
flavonoids,
tannins
evaluated
colorimetric
methods.
For
acute
toxicity
study,
one
oral
dose
2
5
g/kg
administered
mice.
vitro
properties
determined
by
egg
albumin
denaturation
test,
vivo
effect
assessed
carrageenan,
croton
oil,
xylene-induced
edema
tests.
these
natural
compounds
silico
via
molecular
docking
simulations
applying
cyclooxygenase
COX2
inhibitory
impact.
Seven
metabolites
identified:
anthrone,
beta-carotene,
butylated
hydroxyanisole,
butylatedhydroxytoluene,
gallic
acid,
myricetin,
rutin.
ChFA
contained
greatest
quantity
polyphenols
flavonoids
(497.98±0.377
mg
GAE/g
79.89±0.789
QE/g).
While
nBFA
showed
highest
amount
total
(162.89±2.103
TAE/g).
evaluation
revealed
all
had
potent
effect.
No
death,
no
toxicological
symptoms,
appreciable
body
weight
changes
between
treated
control
groups
observed.
Oral
administration
EEAA
(200
mg/kg)
significantly
reduced
induced
xylene.
beta
carotene,
rutin
exhibited
most
promising
inhibition
against
COX2.
Significant
effects
demonstrated
vitro,
vivo,
silico.
ariculata
can
be
regarded
as
non-toxic.
findings
are
consistent
with
plant’s
traditional
applications,
which
include
therapy
illnesses.
