Journal of Pharmacy And Bioallied Sciences,
Год журнала:
2024,
Номер
16(Suppl 2), С. S1204 - S1206
Опубликована: Апрель 1, 2024
A
BSTRACT
Delayed
wound
healing
is
one
of
the
most
common
problems
associated
with
diabetic
patients.
There
are
several
factors
delayed
healing.
It
has
been
observed
that
if
not
cured
takes
a
long
time.
This
reason
researchers
engaged
in
developing
sustainable,
biodegradable,
biocompatible,
and
effective
wound-healing
dressings.
However,
it
traditional
bandages
have
drawbacks
such
as
allergies
less
efficiency
absorption
exudate.
To
fill
gap,
hydrogels
developed
recently
which
higher
capacity.
In
addition,
they
pose
slow
drug
release
properties.
Therefore,
present
study
was
conducted
to
prepare
an
promising
hydrogel
high
Processes,
Год журнала:
2023,
Номер
11(9), С. 2696 - 2696
Опубликована: Сен. 8, 2023
Biomaterials
are
mostly
any
natural
and
synthetic
materials
which
compatible
from
a
biological
point
of
view
with
the
human
body.
widely
used
to
sustain,
increase,
reestablish
or
substitute
function
injured
tissue
organ
Additionally,
biomaterials
uninterruptedly
in
contact
body,
i.e.,
tissue,
blood
fluids.
For
this
reason,
an
essential
feature
is
their
biocompatibility.
Consequently,
review
summarizes
classification
different
types
based
on
origin,
as
ones.
Moreover,
advanced
applications
pharmaceutical
medical
domains
highlighted
specific
mechanical
physical
properties
biomaterials,
concerning
use.
The
high-priority
challenges
field
also
discussed,
especially
those
regarding
transfer
implementation
valuable
scientific
results
practice.
International Journal of Nanomedicine,
Год журнала:
2025,
Номер
Volume 20, С. 3559 - 3574
Опубликована: Март 1, 2025
Tens
of
millions
people
die
from
wound
infections
globally
each
year,
and
nearly
80%
tissue
are
associated
with
bacterial
biofilms.
However,
overuse
antibiotics
can
lead
to
resistance.
Therefore,
it
is
critical
develop
simple
effective
strategies
kill
bacteria
remove
The
present
study
used
sericin
as
a
reducing
stabilizing
agent
synthesize
sericin-gold
nanoparticles
(Ser-Au
NPs)
tested
its
colloidal
stability
under
different
pH
salt
concentration
conditions.
Subsequently,
functional
gold
nanocomposites
(Ser-Au@MMI)
were
synthesized
by
combining
Ser-Au
NPs
2-mercapto-1-methylimidazole
(MMI).
antimicrobial
effect
Ser-Au@MMI
was
checked
MIC,
activity
test,
in
vitro
cytotoxicity
assessed
using
CCK-8
assay.
In
anti-biofilm
observed
fluorescence
microscopy
SEM.
Finally,
the
anti-infective
therapeutic
efficacy
determined
an
vivo
rat-infected
model.
Sericin
exhibited
excellent
TEM,
EDS,
XPS
analyses
confirmed
successful
synthesis
Ser-Au@MMI.
It
higher
antibacterial
due
synergistic
MMI
AuNP,
which
achieve
bactericidal
destroying
integrity
cell
walls
structure.
addition,
Ser-Au@MMI10
(HAuCl4:MMI
=1:10)
(64
μg/mL)
could
effectively
disrupt
biofilms
formed
four
species
them,
including
P.
aeruginosa,
B.
subtilis,
E.
coli,
S.
aureus,
but
not
cytotoxic
mouse
fibroblasts
(L929)
cells.
Infected
modeling
showed
that
accelerated
infected
healing
vivo.
prepared
through
facile
environmentally
friendly
strategy
have
advantages
low
toxicity,
has
potential
for
application
broad-spectrum
biofilm
disrupting
healthcare.
Frontiers in Bioengineering and Biotechnology,
Год журнала:
2024,
Номер
12
Опубликована: Май 28, 2024
Periodontitis
is
an
inflammation-related
condition,
caused
by
infectious
microbiome
and
host
defense
that
causes
damage
to
periodontium.
The
natural
processes
of
the
mouth,
like
saliva
production
eating,
significantly
diminish
therapeutic
medication
residency
in
region
periodontal
disease.
Furthermore,
complexity
diversity
pathological
mechanisms
make
successful
periodontitis
treatment
challenging.
As
a
result,
developing
enhanced
local
drug
delivery
technologies
logical
therapy
procedures
provides
foundation
for
effective
treatment.
Being
biocompatible,
biodegradable,
easily
administered
tissues,
hydrogels
have
sparked
substantial
intense
curiosity
discipline
therapy.
primary
objective
hydrogel
research
has
changed
recent
years
intelligent
thermosensitive
hydrogels,
involve
adjustable
sol-gel
transformations
regulate
release
reaction
temperature,
we
present
thorough
introduction
creation
efficient
construction
new
regeneration.
We
also
address
cutting-edge
smart
options
based
on
pathophysiology.
problems
prospective
study
objectives
are
reviewed,
with
focus
establishing
methods
clinical
applications.
Polysaccharides,
Год журнала:
2024,
Номер
5(1), С. 49 - 66
Опубликована: Март 7, 2024
Amidst
population
growth
and
challenges
with
existing
fertilizers,
the
development
of
smart
environmentally
friendly
agrochemicals
is
imperative.
While
3D
printing
widespread,
its
potential
in
slow-release
remains
unexplored.
This
proof-of-concept
study
employed
solvent
casting
to
develop
agar–urea
structures.
These
structures,
comprising
2.5%
(w/w)
agar,
incorporated
either
7%
or
13%
urea
as
nitrogen
nutrients.
Rheological,
mechanical,
morphological
properties
sorption
capabilities
were
explored.
Rheological
analysis
revealed
a
substantial
impact
urea,
enhancing
material
resistance
deformation.
In
mechanical
tests,
inclusion
showed
no
significant
on
compressive
strength.
SEM
confirmed
successful
entrapment
within
agar
matrix.
The
resulted
diminished
water
capacity,
attributed
urea–water
interactions
disrupting
hydrogen
bonding
ability
agar.
Agar–urea
inks
utilizing
direct-ink
writing
technique,
release
behavior
was
investigated.
Results
nearly
complete
positive
control
48
h.
contrast,
formulations
achieved
rates
88.8%
94.4%,
respectively,
suggesting
for
3D-printed
modify
immediate
seen
conventional
fertilizers.
