An Updated Review Summarizing the Anticancer Potential of Poly(Lactic‐co‐Glycolic Acid) (PLGA) Based Curcumin, Epigallocatechin Gallate, and Resveratrol Nanocarriers DOI
Pratibha Pandey, Meenakshi Verma, Sorabh Lakhanpal

и другие.

Biopolymers, Год журнала: 2024, Номер unknown

Опубликована: Окт. 17, 2024

ABSTRACT The utilization of nanoformulations derived from natural products for the treatment many human diseases, including cancer, is a rapidly developing field. Conventional therapies used cancer have limited efficacy and greater number adverse effects. Hence, it imperative to develop innovative anticancer drugs with superior effectiveness. Among diverse array compounds, resveratrol, curcumin, epigallocatechin gallate (EGCG) gained considerable attention in recent years. Despite their strong properties, medicinally significant phytochemicals such as EGCG certain disadvantages, solubility water, stability, bioavailability problems. Encapsulating these poly(lactic‐ co ‐glycolic acid) (PLGA), polymer that nontoxic, biodegradable, biocompatible, an effective method delivering medication tumor location. In addition, PLGA nanoparticles can be modified targeting molecules specifically target cells, thereby improving effectiveness fighting tumors. Combining plant‐based medicine (phytotherapy) nanotechnology clinical environment has potential enhance improve overall health outcomes patients. Therefore, crucial comprehensive understanding different aspects advancements using PLGA‐based nanocarriers phytochemicals. This review addresses most delivery systems EGCG, emphasizing possibility resolving issues related therapeutic compounds.

Язык: Английский

Amine-functionalized high-surface-area Al2O3 adsorbent for CO2 capture: Effect of the support calcination conditions DOI
Zhongyang Chen, Xinlong Yan, Xiao Hu

и другие.

Separation and Purification Technology, Год журнала: 2024, Номер 342, С. 127064 - 127064

Опубликована: Март 11, 2024

Язык: Английский

Процитировано

4

Improving Curcumin Constraints with pH-Responsive Chitosan Based Graphene Oxide/Montmorillonite Nanohybrid Modified Agarose in Breast Cancer Therapy DOI

Mariyeh Rajaei,

Mehrab Pourmadadi, Hamid Rashedi

и другие.

BioNanoScience, Год журнала: 2024, Номер 14(2), С. 1613 - 1626

Опубликована: Апрель 15, 2024

Язык: Английский

Процитировано

4

Nanoparticles as Drug Delivery Carrier-synthesis, Functionalization and Application DOI

Drishya Sajeevan,

Ramakrishna Prasad Are,

Prabhudutta Hota

и другие.

Current Pharmaceutical Design, Год журнала: 2024, Номер 31(4), С. 244 - 260

Опубликована: Апрель 30, 2024

In recent years, advancements in chemistry have allowed the tailoring of materials at nanoscopic level as needed. There are mainly four main types nanomaterials used drug carriers:metal-based nanomaterials, organic inorganic and polymer nanomaterials. The a carrier showed advantages for decreased side effects with higher therapeutic index. stability compounds increased by encapsulation within nano-drug carriers, leading to systemic toxicity. Nano-drug carriers also controlled release system-made solubility characteristics nanoparticles surface coating surfactants. review focuses on different nanoparticle synthesis process, techniques purposes, applications prospects biomedical applications.

Язык: Английский

Процитировано

4

Surface-modified carbon quantum dot for enhanced fluorescent-sensing of hexagonal valent chromium DOI Open Access

Kangle Shang,

Hansong Chen,

Wenwen Yang

и другие.

Analytical Sciences, Год журнала: 2025, Номер unknown

Опубликована: Янв. 21, 2025

As one of the most harmful heavy metal pollutants, hexavalent chromium Cr(VI) is becoming a serious threat to human health. Thus pursuing remarkably sensitive method monitor concentration in natural conditions favored for fast response prevent harm. In present work, an ethylenediamine (En) and SiO2-modified wool keratin-based carbon quantum dot (CQD)(En@CQDs@SiO2) fluorescent sensor prepared, En found improve discrimination ability by binding with surface carboxyl groups. Based on these designs, En@CQDs@SiO2 achieves significant improvement detection ability, limit 6.08 × 10–4 mg/L, which succeeded 6 times over CQDs, better than conventional UV–Vis flame atomic absorption (AAS) techniques. Furthermore, has good relative sensitivity, selectivity, spectral reproducibility, excellent structural stability. These properties make suitable environmental detection, undoubtedly improves economy friendliness sensor.

Язык: Английский

Процитировано

0

Carbon Quantum Dots Based Materials for Drug Delivery DOI
Mehrab Pourmadadi, Bahareh Farasati Far, Mostafa Khajeh

и другие.

Опубликована: Янв. 1, 2025

Язык: Английский

Процитировано

0

Sustainable Approaches for Pharmaceutical Pollutant Removal: Advances in Chitosan‐Based Nanocomposite Adsorbents DOI

Hossein Dinarvand,

Omid Moradi

ChemistrySelect, Год журнала: 2025, Номер 10(13)

Опубликована: Апрель 1, 2025

Abstract The growing presence of pharmaceutical pollutants in aquatic environments poses significant threats to both human health and ecosystems. Despite their crucial role healthcare, pharmaceuticals enter water systems through various sources, making them some the most critical environmental contaminants. Traditional wastewater treatments, which are classified into physical, chemical, biological techniques, often struggle effectively remove pharmaceuticals. Among these methods, adsorption stands out as a reliable versatile approach for removing organic enhancing efficiency treatment processes. Biopolymers, particularly chitosan, gaining attention due numerous advantages, including biocompatibility, biodegradability, affordability, high capability, non‐toxicity, availability from diverse natural sources. Chitosan, hydrophilic biopolymer, can be chemically modified by incorporating nanoparticles (e.g., metal oxides, carbon‐based materials, magnetic particles) boost its efficiency. These advancements enable chitosan‐based nanocomposites range pharmaceuticals, antibiotics, analgesics, hormones, water. This review examines latest developments nanocomposite adsorbents, emphasizing fundamental mechanisms, optimization conditions, kinetic behaviors, isotherm models. factors collectively determine capturing pollutants. Moreover, underscores potential materials remediation, offering valuable insights application future research directions. Ultimately, aim this is provide insight offer an innovative effective solution challenge contamination By addressing key challenges utilizing advanced material designs, adsorbents hold great promise sustainable efficient removal systems.

Язык: Английский

Процитировано

0

Cell Death Mechanisms Produced by Carbon‐Based Nanoparticles DOI Creative Commons
Santos-Adriana Martel-Estrada, Claudia Vargas-Requena,

Josue-Itan Sifuentes-Chavarría

и другие.

Journal of Nanotechnology, Год журнала: 2025, Номер 2025(1)

Опубликована: Янв. 1, 2025

Using carbon‐based nanoparticles, such as diamond, graphite, fullerene, and nanotubes, has increased their research possible strategies for drug delivery to control diseases, especially cancer. However, because these materials, when interacting with the living environment, release substances that are capable of inducing cell death by themselves, it is vital importance analyze type particle can induce. Although there different efforts describe kind nanoparticles used treat diseases cancer, no paper explains mechanisms induced nanoparticle systems. Therefore, this attempts gain cutting‐edge information on using nanopolymorphisms mechanism particles produce. In conclusion, carbon interact directly membranes, causing physical damage disturbing integrity membrane. This alteration mainly lead necrosis or apoptosis. The definition a predominant each depends dose‐dependent manner. Primarily, concentrations cytotoxicity were 100–500 μg/mL. several studies analyzed, was only find nanodiamonds proved not be cytotoxic.

Язык: Английский

Процитировано

0

Versatile Approaches of Quantum Dots in Biosensing and Imaging DOI
Daphika S. Dkhar, Rohini Kumari, Vinay Patel

и другие.

Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology, Год журнала: 2024, Номер 16(5)

Опубликована: Сен. 1, 2024

Cancer is considered a formidable global health threat, despite substantial strides in diagnosis, detection, and therapeutic strategies. Remarkable progress has been achieved these realms, yet the survival rates for cancer patients have persisted at suboptimal levels over decades. Acknowledging need to address ongoing challenges rates, research efforts are being made push boundaries of innovation diagnostic techniques, bioimaging, drug delivery technologies. Over past few years, nano(bio)technology-based approaches applied biosensing imaging applications detect biochemical substances various matrices. Among nanoengineered particulates, quantum dots (QDs) recognized as versatile agents applications. QDs, often called artificial atoms, characterized by remarkable optical electrical features which essential cytosensing, localized bioimaging therapeutics. Here this review, we discussed QDs sensitive selective precise sensing cells. Both electrochemical used describe cytosensing detection methods. Furthermore, malignant tumor cells with responses also highlighted. This review lists several kinds that frequently such applications, carbon, graphene, zinc, other types hybrid-based QDs. Finally, shed insight on prospective research, advantages potential In article, emphasize limitations difficulties associated clinical order provide insights solutions.

Язык: Английский

Процитировано

3

Novel carboxymethyl cellulose/polyvinyl pyrrolidone hydrogel incorporating graphitic carbon nitride for quercetin delivery DOI

Mohammadreza Salehi,

Mehrab Pourmadadi, Majid Abdouss

и другие.

Inorganic Chemistry Communications, Год журнала: 2023, Номер 160, С. 111932 - 111932

Опубликована: Дек. 18, 2023

Язык: Английский

Процитировано

7

Revolutionizing Cancer Treatment: Biopolymer‐Based Aerogels as Smart Platforms for Targeted Drug Delivery DOI
Hala M. Alkhalidi, Amerh Aiad Alahmadi, Waleed Y. Rizg

и другие.

Macromolecular Rapid Communications, Год журнала: 2024, Номер 45(9)

Опубликована: Март 2, 2024

Abstract Cancer stands as a leading cause of global mortality, with chemotherapy being pivotal treatment approach, either alone or in conjunction other therapies. The primary goal these therapies is to inhibit the growth cancer cells specifically, while minimizing harm healthy dividing cells. Conventional treatments, often causing patient discomfort due side effects, have led researchers explore innovative, targeted cell Thus, biopolymer‐based aerogels emerge innovative platforms, showcasing unique properties that respond intelligently diverse stimuli. This responsiveness enables precise control over release anticancer drugs, enhancing therapeutic outcomes. significance lies their ability offer drug delivery increased efficacy, biocompatibility, and high payload. In this comprehensive review, author discuss role an emerging functionalized platforms delivery. review addresses showing smart behavior responding different stimuli including temperature, pH, magnetic redox potential release. Finally, discusses application aerogel delivering drugs also gene applications.

Язык: Английский

Процитировано

2