Abstract
Hydrogel
dressings
play
an
important
role
in
the
treatment
of
bacterial
infection.
In
this
study,
carboxymethyl
chitosan
(CM‐CS)
was
cross‐linked
with
aldehyde
polyglycol
(DF‐PEG),
and
then
polydopamine
(pDA)
5,10,15,
20‐tetrakis
(4‐aminophenyl)
porphyrin
(TAPP)
were
grafted
to
prepare
a
CM‐CS/DF‐PEG/pDA/TAPP
hydrogel
(CDPT).
The
results
showed
that
CDPT
had
good
adhesion,
injectability,
self‐healing,
degradability,
biocompatibility.
Under
near‐infrared
irradiation,
has
excellent
photothermal
photodynamic
effects
can
effectively
inhibit
activity
Staphylococcus
aureus
(S.
aureus)
,
Escherichia
coli
(
E.
)
antibiotic‐resistant,
methicillin‐resistant
(MRSA)
.
summary,
potential
applications
as
antibacterial
material.
Journal of Materials Chemistry B,
Год журнала:
2024,
Номер
12(9), С. 2384 - 2393
Опубликована: Янв. 1, 2024
Coaxial
electrospinning
produced
biodegradable
nanofibers
(PSTs)
with
a
core–shell
structure.
These
PSTs
exhibited
anti-oxidative
properties
as
well
outstanding
biocompatibility
and
excellent
mechanical
properties.
Journal of Biomaterials Science Polymer Edition,
Год журнала:
2025,
Номер
unknown, С. 1 - 22
Опубликована: Фев. 10, 2025
Cerebrospinal
fluid
(CSF)
leakage
caused
by
accidents
or
diseases
resulting
from
traumatic
brain
injury,
inflammation,
tumor
erosion
and
surgery
can
lead
to
many
complications.
In
this
study,
a
multifunctional
composite
double-layer
hydrogel
was
designed
simulating
the
structure
of
native
dura
mater,
which
composed
polyacrylic
acid
(PAA),
polyethyleneimine
(PEI),
sodium
alginate
(SA),
β-cyclodextrin
(β-CD)
edaravone
(Ed).
The
PAA/PEI
layer
had
strong
wet
adhesion
characteristics,
while
PEI/SA@β-CD/Ed
exhibited
significant
antioxidant,
drug
release
biocompatibility
properties.
By
controlling
concentration
Ca2+,
gelation
time
be
adjusted
rapidly
within
95-215
s.
Specifically,
final
PAA/PEI/SA@β-CD/Ed
porous
network
with
high
porosity
low
swelling
rate,
improved
tensile
strength,
sufficient
biodegradability,
favourable
performance,
enhanced
DPPH
ABTS
radicals
scavenging
abilities,
sustained
Ed
capacity.
addition,
also
showed
excellent
protective
effect
on
H2O2-induced
oxidative
damage
in
SH-SY5Y
cells.
These
results
preliminarily
suggested
that
would
appear
promising
candidate
for
dural
repair.
Biomacromolecules,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 17, 2025
The
skin
is
fragile,
making
it
very
vulnerable
to
damage
and
injury.
Untreated
wounds
can
pose
a
serious
threat
human
health.
Three-dimensional
polymer
network
hydrogels
have
broad
application
prospects
in
wound
dressings
due
their
unique
properties
structure.
therapeutic
effect
of
traditional
limited,
while
multifunctional
composite
show
greater
potential.
Multifunctional
regulate
moisture
through
formula
adjustment.
Moreover,
be
combined
with
bioactive
ingredients
improve
performance
healing
applications.
Stimulus-responsive
respond
specifically
the
environment
meet
needs
different
stages.
This
review
summarizes
material
types,
structure,
properties,
design
considerations,
formulation
strategies
for
hydrogel
used
healing.
We
discuss
various
types
recently
developed
dressings,
highlights
importance
tailoring
physicochemical
addresses
potential
challenges
preparing
dressings.
