Deleted Journal, Год журнала: 2024, Номер unknown
Опубликована: Дек. 19, 2024
Hydrogels possessing both conductive characteristics and notable self-healing to achieve high wound closure effectiveness is highly desirable in clinical applications. In this work, the stretchable hydrogel dressings were designed through dual-dynamic-bond cross-linking. A stable tricomplex molecule (PA@Fe) could be formed by pH-sensitive coordinate bond (catechol-Fe) between catechol groups PA ferric ions (Fe3+). And hydrogels with properties fabricated cross-linking of aldehyde PA@Fe gelatin dynamic Schiff base bonds integration poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS). The as-prepared exhibited good self-healing, adhesive ability, biocompatibility, hemostatic, electrical conductivity. vivo evaluation a full-thickness skin model revealed post-wound-closure care smart hydrogels, demonstrating its great potential dealing wounds.
Язык: Английский