Extraction methods, structural features and bioactivity diversity of polysaccharides from the genus Chrysanthemum: A review

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 139423 - 139423

Опубликована: Янв. 1, 2025

Язык: Английский

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Interplay between traditional Chinese medicine polysaccharides and gut microbiota: The elusive “polysaccharides‐bond‐bacteria‐enzyme” equation

Phytotherapy Research, Год журнала: 2024, Номер 38(9), С. 4695 - 4715

Опубликована: Авг. 9, 2024

Polysaccharides are one of the most important components traditional Chinese medicine (TCM) and have been extensively studied for their immunomodulatory properties. The functions effects TCM polysaccharides closely related to gut microbiota, making study interaction a hot topic in field metabolism. This review follows two main inquiries: first, how microbiota breaks down produce bioactive metabolites; second, reshape as carbon source. Understanding mechanism involves challenging equation structural association with metabolic activities microbiota. has meticulously searched, partially organized literature spanning past decade, that delves into between It also gives an overview complex factors elusive "polysaccharides-bond-bacteria-enzyme" equation: complexity polysaccharide structures, diversity glycosidic bond types, communal nature metabolizing enzymes involved functional degradation by hierarchical roles utilization locus gram-positive PULs. Finally, this aims facilitate discussion among peers offers prospects research fields, paving way pharmacological studies on therapeutics, providing reference point further clinical research.

Язык: Английский

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Optimization of Intercropping Modes in Placodon grandiflorus

Plant-Environment Interactions, Год журнала: 2025, Номер 6(1)

Опубликована: Фев. 1, 2025

ABSTRACT Intercropping enhances plant growth, increases yield, and boosts the accumulation of secondary metabolites. Platycodon grandiflorus ( P. ), a traditional Chinese medicinal herb, has limited research available regarding its intercropping practices. We aimed to (1) examine changes in physiological biochemical indicators growth during process , (2) assess quality when intercropped with different crops, (3) evaluate optimal mode for . This study utilized two‐year seedlings as test material field study. The treatments included monoculture (JG‐JG), Achyranthes bidentata (JG‐NX), Saposhnikovia divaricata (JG‐FF), Adenophora stricta (JG‐SS), Zea mays (JG‐YM), Setaria italica (JG‐GZ), Glycine max (JG‐DD). investigated effects these modes on indicators, five saponins at various development stages. Compared JG‐JG, chlorophyll MDA contents significantly increased decreased, respectively, JG‐YM, JG‐DD, JG‐NX treatments. All three enhanced biomass exhibited higher levels antioxidant enzyme activity osmoregulatory substance content. JG‐YM JG‐SS p < 0.05) improved notably maintaining high content platycodin D. results this provide scientific basis optimizing planting systems advancing sustainable medicine industry.

Язык: Английский

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Platycodonis Radix Polysaccharides Suppress Progression of High-Fat-induced Obesity Through Modulation of Intestinal Microbiota and Metabolites

Phytomedicine, Год журнала: 2025, Номер unknown, С. 156653 - 156653

Опубликована: Март 1, 2025

Язык: Английский

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Platycodin D ameliorates polycystic ovary syndrome-induced ovarian damage by upregulating CD44 to attenuate ferroptosis

Free Radical Biology and Medicine, Год журнала: 2024, Номер 224, С. 707 - 722

Опубликована: Сен. 24, 2024

Язык: Английский

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Selenium polysaccharide form sweet corn cob mediated hypoglycemic effects in vitro and untargeted metabolomics study on type 2 diabetes

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 281, С. 136388 - 136388

Опубликована: Окт. 9, 2024

Язык: Английский

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Extraction methods, structural characteristics, biological activities, and applications of the polysaccharides from Gracilaria lemaneiformis: A review

International Journal of Biological Macromolecules, Год журнала: 2024, Номер unknown, С. 139316 - 139316

Опубликована: Дек. 1, 2024

Язык: Английский

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Research Progress on Structure and Bioactivity of Polysaccharides from Platycodon grandiflorum

Starch - Stärke, Год журнала: 2024, Номер unknown

Опубликована: Сен. 13, 2024

Abstract Platycodon grandiflorum is a commonly used Chinese herbal medicine in China, containing saponins, flavonoids, phenolic compounds, fatty acids, volatile oils, polysaccharides, and other active ingredients. It has the effects of regulating immunity, anti‐inflammatory, expectorant, lowering blood lipids, antioxidation, etc., can be to treat symptoms such as cough, sore throat, lung pain, expectoration. Polysaccharides are one important bioactive substances P. , which have better anti‐tumor enhancing immune activity, widely medicine, health food, fields. polysaccharide (PGP) various biological activities main component key substance . effects, including regulation, antioxidant, anti‐tumor, liver protection, hypoglycemic, gastrointestinal protection. This paper systematically reviews research progress on extraction, separation purification, structural characteristics, activity polysaccharides recent years both domestically internationally, provide theoretical basis for improving utilization further studying structure–activity relationship polysaccharides.

Язык: Английский

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Effects and mechanism of combination of Platycodon grandiflorum polysaccharides and Platycodon saponins in the treatment of chronic obstructive pulmonary disease rats through the gut-lung axis

Journal of Ethnopharmacology, Год журнала: 2024, Номер unknown, С. 119305 - 119305

Опубликована: Дек. 1, 2024

Язык: Английский

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