Catalysts,
Год журнала:
2024,
Номер
14(6), С. 371 - 371
Опубликована: Июнь 10, 2024
Chitin
and
chitosan,
abundant
biopolymers
derived
from
the
shells
of
crustaceans
cell
walls
fungi,
have
garnered
considerable
attention
in
pharmaceutical
circles
due
to
their
biocompatibility,
biodegradability,
versatile
properties.
Deep
eutectic
solvents
(DESs),
emerging
green
composed
mixtures
hydrogen
bond
acceptors
donors,
offer
promising
avenues
for
enhancing
solubility
functionality
chitin
chitosan
formulations.
This
review
delves
into
potential
utilizing
DESs
as
highlighting
efficiency
dissolving
these
polymers,
which
facilitates
production
novel
drug
delivery
systems,
wound
dressings,
tissue
engineering
scaffolds,
antimicrobial
agents.
The
distinctive
physicochemical
properties
DESs,
including
low
toxicity,
volatility,
adaptable
solvation
power,
enable
customization
chitosan-based
materials
meet
specific
requirements.
Moreover,
environmentally
friendly
nature
aligns
with
growing
demand
sustainable
eco-friendly
processes
manufacturing.
revision
underscores
recent
advances
illustrating
role
evolving
applications
laying
groundwork
development
innovative
systems
biomedical
enhanced
efficacy
safety
profiles.
Frontiers in Bioengineering and Biotechnology,
Год журнала:
2024,
Номер
12
Опубликована: Май 17, 2024
Periodontal
defects
involve
the
damage
and
loss
of
periodontal
tissue,
primarily
caused
by
periodontitis.
This
inflammatory
disease,
resulting
from
various
factors,
can
lead
to
irreversible
harm
tissues
supporting
teeth
if
not
treated
effectively,
potentially
in
tooth
or
loosening.
Such
outcomes
significantly
impact
a
patient’s
facial
appearance
their
ability
eat
speak.
Current
clinical
treatments
for
periodontitis,
including
surgery,
root
planing,
types
curettage,
as
well
local
antibiotic
injections,
aim
mitigate
symptoms
halt
disease
progression.
However,
these
methods
fall
short
fully
restoring
original
structure
functionality
affected
due
complex
deep
pockets
intricate
nature
tissue.
To
overcome
limitations,
numerous
biomaterials
have
been
explored
tissue
regeneration,
with
hydrogels
being
particularly
noteworthy.
Hydrogels
are
favored
research
exceptional
absorption
capacity,
biodegradability,
tunable
mechanical
properties.
They
shown
promise
barrier
membranes,
scaffolds,
carriers
cell
transplantation
drug
delivery
systems
regeneration
therapy.
The
review
concludes
discussing
ongoing
challenges
future
prospects
hydrogel
applications
treatment.
Frontiers in Chemistry,
Год журнала:
2024,
Номер
12
Опубликована: Ноя. 20, 2024
The
extensive
utilization
of
natural
polymers
in
tissue
engineering
is
attributed
to
their
excellent
biocompatibility,
degradability,
and
resemblance
the
extracellular
matrix.
These
have
a
wide
range
applications
such
as
delivering
therapeutic
medicine,
detecting
diseases,
sensing
biological
substances,
promoting
regeneration,
treating
diseases.
This
brief
review
current
developments
properties
uses
widely
used
biomedical
derived
from
nature.
Additionally,
it
explores
correlation
between
characteristics
functions
these
materials
different
highlights
prospective
direction
for
advancement
polymer
engineering.
Materials,
Год журнала:
2025,
Номер
18(4), С. 823 - 823
Опубликована: Фев. 13, 2025
Significant
progress
has
been
achieved
in
the
development
of
superabsorbent
polymers
(SAPs),
focusing
on
enhancing
their
performance
and
expanding
applications.
Efforts
are
particularly
directed
at
increasing
water
absorbency
while
promoting
environmental
sustainability.
Biodegradable
materials
such
as
starch
potassium
humate
have
successfully
integrated
with
SAPs
for
desert
greening,
improving
retention,
salt
resistance,
seedling
survival.
The
inclusion
nutrient-rich
organic-inorganic
composites
further
enhances
durability,
efficiency,
recyclability
SAPs.
In
drought
mitigation,
polymeric
absorbent
resins
polyacrylamide
starch-grafted
acrylates
shown
efficacy
ameliorating
soil
conditions
fostering
plant
growth.
arid
environments,
agents
enriched
humic
acid
bentonite
contribute
to
improved
aeration
creating
optimal
establishment.
Additionally,
adoption
innovative
waste
management
solutions
led
production
amphiphilic
from
residual
sludge,
effectively
addressing
nutrient
deficiencies
pollution.
food
industry,
containing
protease,
tea
polyphenols,
chitosan
exhibit
potential
stability
quality
seafood
products.
These
advancements
highlight
growing
relevance
structural
optimization
approaches
SAP
across
diverse
applications
underline
importance
continued
innovation
these
fields.
As
novel
emerge
challenges
intensify,
anticipated
expand
significantly.
Macromolecular Rapid Communications,
Год журнала:
2025,
Номер
unknown
Опубликована: Фев. 20, 2025
Abstract
There
is
intense
research
during
the
past
few
decades
to
design
and
fabricate
drug
delivery
systems
using
electrospinning
system.
Electrospinning
an
efficient
technique
produce
nanofiber
materials
with
different
dimensions
morphologies
by
adjusting
processing
parameters.
becoming
innovative
technology
that
promotes
pursuit
maintenance
of
human
health.
Herein,
review
discusses
contribution
in
systems,
summarising
modification
various
system
configurations
effects
process
parameters
on
fibers,
their
application
including
carrier
materials,
loaded
drugs
release
mechanisms
illustrates
medical
applications.
Finally,
this
challenges,
bottlenecks,
development
prospects
field
terms
scaling
up
for
clinical
use
exploring
potential
solutions
pave
way
establish
future
systems.
Pharmaceutical Development and Technology,
Год журнала:
2025,
Номер
unknown, С. 1 - 50
Опубликована: Март 31, 2025
Thymus
capitatus
(Th.
Ca)
is
known
to
treat
mouth
ulcers
and
respiratory
infections
in
Cyprus.
However,
antioxidant,
antibacterial
cytotoxic
potential
of
Th.
Ca.
EO
on
MDA-MB-231
cells
its'
encapsulation
into
nanoparticles
has
not
been
well
studied.
Therefore,
we
aimed
analyse
the
antibacterial,
potential,
loading
efficiency
vitro
release
profile
both
Chitosan
Nanoparticle
(Ch.
Np)
-
EO.
GC-MS
analysis
revealed
53.97%
carvacrol,
14.53%
borneol
12.09%
sabinene
presence
The
Ch.
Np.
was
calculated
as
35.27%
reached
a
maximum
68%
pH
7
for
two
weeks.
Minimum
Inhibitory
Concentration
(MIC)
assay
showed
that
E.
coli
had
an
MIC50
0.3215
mg/ml
while
B.
subtilis
0.5304
mg/ml.
antioxidant
activity
assessed
by
performing
DPPH
with
IC50
=
440
μg/ml.
Trypan
Blue
Assay
60
µg/ml
significantly
reduced
cell
viability
10.7%
at
48h
20.06%
72h.
Overall,
shown
promising
formulation
pharmaceutical
industry.
Abstract
The
growing
presence
of
pharmaceutical
pollutants
in
aquatic
environments
poses
significant
threats
to
both
human
health
and
ecosystems.
Despite
their
crucial
role
healthcare,
pharmaceuticals
enter
water
systems
through
various
sources,
making
them
some
the
most
critical
environmental
contaminants.
Traditional
wastewater
treatments,
which
are
classified
into
physical,
chemical,
biological
techniques,
often
struggle
effectively
remove
pharmaceuticals.
Among
these
methods,
adsorption
stands
out
as
a
reliable
versatile
approach
for
removing
organic
enhancing
efficiency
treatment
processes.
Biopolymers,
particularly
chitosan,
gaining
attention
due
numerous
advantages,
including
biocompatibility,
biodegradability,
affordability,
high
capability,
non‐toxicity,
availability
from
diverse
natural
sources.
Chitosan,
hydrophilic
biopolymer,
can
be
chemically
modified
by
incorporating
nanoparticles
(e.g.,
metal
oxides,
carbon‐based
materials,
magnetic
particles)
boost
its
efficiency.
These
advancements
enable
chitosan‐based
nanocomposites
range
pharmaceuticals,
antibiotics,
analgesics,
hormones,
water.
This
review
examines
latest
developments
nanocomposite
adsorbents,
emphasizing
fundamental
mechanisms,
optimization
conditions,
kinetic
behaviors,
isotherm
models.
factors
collectively
determine
capturing
pollutants.
Moreover,
underscores
potential
materials
remediation,
offering
valuable
insights
application
future
research
directions.
Ultimately,
aim
this
is
provide
insight
offer
an
innovative
effective
solution
challenge
contamination
By
addressing
key
challenges
utilizing
advanced
material
designs,
adsorbents
hold
great
promise
sustainable
efficient
removal
systems.
