Biomolecules,
Год журнала:
2024,
Номер
14(9), С. 1129 - 1129
Опубликована: Сен. 6, 2024
Conventional
pulp
capping
materials
have
limited
anti-inflammatory
capacity.
It
is
necessary
to
develop
more
effective
material
for
the
treatment
of
inflamed
pulps.
Tannic
acid
(TA)
a
natural,
water-soluble
polyphenol
with
antimicrobial
and
properties.
This
study
aimed
investigate
effects
tannin-containing
hydroxypropyl
chitin
hydrogel
(HPCH/TA
hydrogel)
as
an
innovative
material.
The
physicochemical
properties
composite
hydrogels
were
characterized.
HPCH/TA
evaluated
in
vitro
vivo.
underlying
mechanism
was
explored.
demonstrated
favorable
temperature
sensitivity,
injectability,
antibacterial
In
vitro,
effectively
promoted
proliferation
human
dental
cells
inhibited
interleukin-1β,
interleukin-6,
tumor
necrosis
factor-α
expression,
possibly
by
suppressing
nuclear
factor
kappa-B
pathway.
vivo,
on
fourth
day
after
capping,
group
showed
lower
inflammatory
scores
compared
control
iRoot
BP
Plus
(commercial
material)
group.
By
sixth
week,
complete
reparative
dentin
formation
observed
group,
no
difference
thickness
Collectively,
holds
promise
bioactive
promoting
repair
vital
therapy.
Advanced Healthcare Materials,
Год журнала:
2024,
Номер
unknown
Опубликована: Дек. 26, 2024
Porous
polymers,
including
hydrogels,
covalent
organic
frameworks
(COFs),
and
hyper
crosslinked
polymers
(HCPs),
have
become
essential
in
biomedical
research
for
their
tunable
pore
architectures,
large
surface
areas,
functional
versatility.
This
review
provides
a
comprehensive
overview
of
classification
updated
synthesis
mechanisms,
such
as
3D
printing,
electrospinning,
molecular
imprinting.
Their
pivotal
roles
drug
delivery,
tissue
engineering,
wound
healing,
photodynamic/photothermal
therapies,
focusing
on
how
size,
distribution,
architecture
impact
release,
cellular
interactions,
therapeutic
outcomes,
are
explored.
Key
challenges,
biocompatibility,
mechanical
strength,
controlled
degradation,
scalability,
critically
assessed
alongside
emerging
strategies
to
enhance
clinical
potential.
Finally,
recent
challenges
future
perspectives,
emphasizing
the
broader
applications
porous
addressed.
work
valuable
insights
advancing
next-generation
innovations
through
these
materials.
Molecular & cellular biomechanics,
Год журнала:
2024,
Номер
21, С. 158 - 158
Опубликована: Авг. 6, 2024
Evaluating
people’s
food
intake
is
crucial
for
establishing
the
link
between
diet
and
disease.
Deprivation
of
vital
nutrients
causes
body
to
deteriorate
organs
increases
risk
severe
diseases
that
manifest
in
maturity.
Making
healthy
choices
one
best
ways
avoid
developing
chronic
diseases,
such
as
diabetes,
heart
disease,
stroke,
even
certain
types
cancer.
Hence,
this
paper
proposes
a
deep
learning-based
automated
nutrition
classification
system
(DL-ANCS)
predicting
ingredients
nutrition.
The
DL-ANCS
with
Internet
Things
(IoT)
sensors
quantify
smartphone
app
compile
ingredient
nutritional
information.
It
possible
take
pictures
eaten
using
camera
comes
most
mobile
phones.
automatically
identify
items
record
keeping
image
processing.
effectiveness
proposed
relies
on
its
ability
accurately
classify
these
photos
utilizing
meal
prediction
algorithms
DL-ANCS.
This
research
introduces
novel
approach
extracting
texture
information
from
show
how
features
improve
accuracy
assessment
runs
method
improvesthe
ratio
98.7%,
99.2%,
95.89%,
predictionsand
their
compatibility
96.8%,
component
classifications
97.29%.
ACS Biomaterials Science & Engineering,
Год журнала:
2024,
Номер
10(9), С. 5513 - 5536
Опубликована: Авг. 22, 2024
Irreversible
bone
defects
resulting
from
trauma,
infection,
and
degenerative
illnesses
have
emerged
as
a
significant
health
concern.
Structurally
functionally
controllable
hydrogels
made
by
tissue
engineering
(BTE)
become
promising
biomaterials.
Natural
proteins
are
able
to
establish
connections
with
autologous
through
unique
biologically
active
regions.
Hydrogels
based
on
can
simulate
the
microenvironment
regulate
biological
behavior
of
stem
cells
in
niche,
making
them
candidates
for
research
related
regeneration.
This
article
reviews
functions
various
natural
macromolecular
(such
collagen,
gelatin,
fibrin,
silk
fibroin)
highlights
their
special
advantages
hydrogels.
Then
latest
trends
cross-linking
modified
protein
improved
mechanical
properties
composite
loaded
exogenous
micromolecular
been
discussed.
Finally,
applications
hydrogels,
such
3D
printed
microspheres,
injectable
were
introduced,
aiming
provide
reference
repair
clinical
defects.
Biomolecules,
Год журнала:
2024,
Номер
14(9), С. 1129 - 1129
Опубликована: Сен. 6, 2024
Conventional
pulp
capping
materials
have
limited
anti-inflammatory
capacity.
It
is
necessary
to
develop
more
effective
material
for
the
treatment
of
inflamed
pulps.
Tannic
acid
(TA)
a
natural,
water-soluble
polyphenol
with
antimicrobial
and
properties.
This
study
aimed
investigate
effects
tannin-containing
hydroxypropyl
chitin
hydrogel
(HPCH/TA
hydrogel)
as
an
innovative
material.
The
physicochemical
properties
composite
hydrogels
were
characterized.
HPCH/TA
evaluated
in
vitro
vivo.
underlying
mechanism
was
explored.
demonstrated
favorable
temperature
sensitivity,
injectability,
antibacterial
In
vitro,
effectively
promoted
proliferation
human
dental
cells
inhibited
interleukin-1β,
interleukin-6,
tumor
necrosis
factor-α
expression,
possibly
by
suppressing
nuclear
factor
kappa-B
pathway.
vivo,
on
fourth
day
after
capping,
group
showed
lower
inflammatory
scores
compared
control
iRoot
BP
Plus
(commercial
material)
group.
By
sixth
week,
complete
reparative
dentin
formation
observed
group,
no
difference
thickness
Collectively,
holds
promise
bioactive
promoting
repair
vital
therapy.
