BULLETIN OF STOMATOLOGY AND MAXILLOFACIAL SURGERY, Год журнала: 2025, Номер unknown, С. 277 - 283

Опубликована: Март 20, 2025

Background: Periodontitis is a severe gum infection that damages the soft tissue and, if untreated, can destroy bone supports your teeth.Cissus quadrangularis, medicinal plant known for its healing properties, has been used in traditional medicine centuries. Antibiotic-laden membranes have gained significant attention due to their ability prevent infections, which are major challenge orthopedic surgeries and grafting procedures. The main aim of study fabricate characterize triple antibiotic Cissus quadrangularis conjugated lyophilized membrane periodontal regeneration. Materials Methods: 10mg was weighed dispersed 100 ml deionised waste heated at 50 degree centigrade 24 hrs then extract collected using filtration method with wattmann filter paper. 1 g PEG Carrageenan (2 g) dissolved mL cissus 60 ◦C magnetic stirrer under 400 rpm . Triple antibiotics were also added. Following 24-hour period, petri plate dried 12 hours 50°C. removed from dish placed desiccator. formation FTIR, contact angle, Antimicrobial activity compared between carrageenan (control group) Group 2 consisted membrane, antibiotic, (test group). Results: Tensile strength control group 14.62 N Test 32.13 N. Hence more tensile than test membrane. showed an angle average 75.27 Control 46.51degree. indicates better hydrophilic nature material. antimicrobial against tested bacteria (Streptococcus mutans). Conclusion: present results higher strength, good property enhanced wettability prepared novel when group. By addressing both prevention promotion healing, this builds on existing research offers promising solution use guided regeneration

Язык: Английский