Physicochemical Properties and Cytoprotective Effects on PC12 Cells of Polysaccharides from Belamcanda chinensis (L.) DC. Obtained via a Gradient Ethanol Precipitation Method

Molecules, Год журнала: 2025, Номер 30(5), С. 998 - 998

Опубликована: Фев. 21, 2025

Given that the preparation method of polysaccharides affects functional properties, four types acidic (BCP30-1a, BCP50-1a, BCP70-1a, and BCP90-1a) were prepared using gradient ethanol precipitation method. Then, a series chemical instrumental analysis techniques used to compare structural characteristics morphology. Neuroprotective effects explored OGD/R-induced PC12 cells. The results showed BCP30-1a, BCP90-1a had similar characteristic groups contained both β-glycosidic α-glycosidic bonds. Their molecular weights, in descending order, 198.398 kDa, 184.690 184.556 184.217 respectively. In addition, different proportions glycosidic bonds, namely, Manp-(1→, →5)-Araf-(1→, →3)-Galp (or GalAp)-(1→, →4)-Glcp-(1→ →3,6)-Galp-(1→. BCP30-1a also certain proportion Galp-(1→, each polysaccharide microscopic good thermal stability. Finally, exhibited cytoprotective on cells based OGD/R model. These findings provide novel regulatory strategy for activity BCPs offer scientific evidence supporting application research field ischemic stroke.

Язык: Английский

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Potential Natural Plant Polysaccharides for Use as Feed Additives in Aquaculture: Structure–Activity Relationship, Benefits, and Restrictions

Reviews in Aquaculture, Год журнала: 2025, Номер 17(2)

Опубликована: Март 1, 2025

ABSTRACT Some potential natural plant polysaccharides (PNPP) exhibit a diverse array of beneficial biological activities and are increasingly utilized as feed additives in environmentally sustainable aquaculture. This review summarizes the extraction purification methods, well processes involved obtaining polysaccharides. Subsequently, we provide an in‐depth discussion on relationship between structural characteristics PNPP their associated activities. Following this, highlight advantageous effects Astragalus polysaccharides, Lycium barbarum other within aquaculture settings. We also briefly elucidate pathways mechanisms underlying these based properties. Finally, outline limitations currently faced applying to aquatic farming while proposing future directions for development this field. aims enhance understanding offers theoretical foundation forthcoming research applications

Язык: Английский

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Isolation of endophytes from Taxus cuspidata cv. Nana, preparation of extracellular polysaccharides and study on their functional properties

International Journal of Biological Macromolecules, Год журнала: 2025, Номер unknown, С. 142494 - 142494

Опубликована: Март 1, 2025

Язык: Английский

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Purification, Structural Analysis and Bioactivity of Pueraria montana Polysaccharide

Foods, Год журнала: 2025, Номер 14(8), С. 1359 - 1359

Опубликована: Апрель 15, 2025

Pueraria montana is a medicinal and edible plant widely distributed in Asia. It has antipyretic, analgesic, anti-inflammatory properties. In this study, novel polysaccharide (PMPS-A1) was obtained through purification, its biological activity investigated. Structural analysis revealed that PMPS-A1 composed of fructose glucose, with molecular weight 12168 Da. The main chain structure →1)-β-D-Fruf-(2→, →4)-α-D-Glcp-(1→, →4)-α-D-Glcp-(1→. branched α-D-Glcp-(1→3)-α-D-Glcp-(1→ α-D-Glcp-(1→ connected to the O-3 O-6 positions residue →3,4)-α-D-Glcp-(1→ →4,6)-α-D-Glcp-(1→, respectively. vitro, had favorable scavenging ability hydroxyl radical 1,1-diphenyl-2-picrylhydrazyl (DPPH) downregulated expression interleukin-6 nitric oxide lipopolysaccharide-induced RAW264.7 macrophages. addition, Caenorhabditis model assay demonstrated decreased buildup lipofuscin reactive oxygen species. Overall, these results enhance our knowledge chemical composition bioactivity point potential use for antioxidant anti-aging qualities, providing theoretical basis application polysaccharide.

Язык: Английский

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Comparative Analysis of Three Extraction Methods for Ginger Leaf Polysaccharide: Chemical Composition, Antioxidant activity, and Hypolipidemic Effects

Journal of Applied Research on Medicinal and Aromatic Plants, Год журнала: 2025, Номер unknown, С. 100639 - 100639

Опубликована: Апрель 1, 2025

Язык: Английский

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Chemical composition, rheological properties and calcium-induced gelation mechanism of Premna microphylla Turcz polysaccharide

Food Hydrocolloids, Год журнала: 2024, Номер unknown, С. 110882 - 110882

Опубликована: Ноя. 1, 2024

Язык: Английский

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Enzymatic grafting of 5-O-succinyl erythorbyl myristate onto chitosan to improve its emulsifying properties

Carbohydrate Polymers, Год журнала: 2024, Номер 351, С. 123093 - 123093

Опубликована: Дек. 6, 2024

Язык: Английский

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