Bimetallic MOF-Based Hybrid Platform with Dual Stimuli-Responsiveness for Sustained Release and Enhanced Retention DOI

Vinayak Hegde,

Mahesh P. Bhat, Jae Ho Lee

и другие.

ACS Applied Materials & Interfaces, Год журнала: 2025, Номер unknown

Опубликована: Март 24, 2025

Pesticide delivery carriers provide protection against pathogens but face significant challenges, including limited loading capacity, rapid release rates, and inconsistent performance. To address these issues, this study develops a dual-stimuli-responsive pesticide carrier, featuring an iron-copper bimetal-organic framework (Fe-Cu MOF) supported on diatomaceous earth (DE) coated with lauric acid (LA). Here, DE serves as biocompatible scaffold, enhancing the adhesion retention of MOF particles at target sites, thereby improving localization efficiency. The carrier exhibits high thiabendazole (Tbz) capacity 38.14% owing to its nanoporous structure. LA coating functions pH- temperature-responsive barrier, regulating prolong treatment duration minimizing need for repeated applications. demonstrates controlled rates 80.73% pH 5 96.55% 40 °C, confirming dual-stimuli responsiveness. In vitro assays reveal 92.26% inhibition Botrytis cinerea 1 μg mL-1, while in vivo experiments tomato plants fruits show complete 200 mL-1. Additionally, developed composites adhere strongly leaves through electrostatic hydrogen-bonding interactions, reducing loss due rain erosion. Overall, DE-MOF-Tbz-LA presents promising efficient alternative conventional

Язык: Английский

Bimetallic MOF-Based Hybrid Platform with Dual Stimuli-Responsiveness for Sustained Release and Enhanced Retention DOI

Vinayak Hegde,

Mahesh P. Bhat, Jae Ho Lee

и другие.

ACS Applied Materials & Interfaces, Год журнала: 2025, Номер unknown

Опубликована: Март 24, 2025

Pesticide delivery carriers provide protection against pathogens but face significant challenges, including limited loading capacity, rapid release rates, and inconsistent performance. To address these issues, this study develops a dual-stimuli-responsive pesticide carrier, featuring an iron-copper bimetal-organic framework (Fe-Cu MOF) supported on diatomaceous earth (DE) coated with lauric acid (LA). Here, DE serves as biocompatible scaffold, enhancing the adhesion retention of MOF particles at target sites, thereby improving localization efficiency. The carrier exhibits high thiabendazole (Tbz) capacity 38.14% owing to its nanoporous structure. LA coating functions pH- temperature-responsive barrier, regulating prolong treatment duration minimizing need for repeated applications. demonstrates controlled rates 80.73% pH 5 96.55% 40 °C, confirming dual-stimuli responsiveness. In vitro assays reveal 92.26% inhibition Botrytis cinerea 1 μg mL-1, while in vivo experiments tomato plants fruits show complete 200 mL-1. Additionally, developed composites adhere strongly leaves through electrostatic hydrogen-bonding interactions, reducing loss due rain erosion. Overall, DE-MOF-Tbz-LA presents promising efficient alternative conventional

Язык: Английский

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