Dietary AGEs and food allergy: insights into the mechanisms of AGEs-induced food allergy and mitigation strategies DOI
Lichun Liu,

Ziye Zhang,

Hang Xiao

и другие.

Critical Reviews in Food Science and Nutrition, Год журнала: 2025, Номер unknown, С. 1 - 18

Опубликована: Март 24, 2025

Food allergy (FA) is a significant public health concern, with over one billion individuals globally affected, and its prevalence continues to rise. Advanced glycation end products (AGEs) are common hazards in various diet. Recent investigations have shown that AGEs could influence the pathogenesis of FA by interacting receptors. This paper provides comprehensive review recent advances on diet AGEs, summarized mechanisms regulating food mitigation strategies, analyzed limitations current research prospected future research. combine receptors for (RAGE) induce oxidative stress, inflammation allergic signaling pathways. can affect allergen epitopes conformation regulate intestinal flora non-receptor-dependent manner, as well barrier Th1/Th2 immune balance through receptor-dependent pathways allergy. Currently, approaches reduce AGEs-induced mainly depended improving processing methods (e.g., low temperature, short time, pH non-thermal methods), natural inhibitors RAGE inhibitors. elucidates influences which provide novel insights into reducing induced AGEs.

Язык: Английский

Dietary AGEs and food allergy: insights into the mechanisms of AGEs-induced food allergy and mitigation strategies DOI
Lichun Liu,

Ziye Zhang,

Hang Xiao

и другие.

Critical Reviews in Food Science and Nutrition, Год журнала: 2025, Номер unknown, С. 1 - 18

Опубликована: Март 24, 2025

Food allergy (FA) is a significant public health concern, with over one billion individuals globally affected, and its prevalence continues to rise. Advanced glycation end products (AGEs) are common hazards in various diet. Recent investigations have shown that AGEs could influence the pathogenesis of FA by interacting receptors. This paper provides comprehensive review recent advances on diet AGEs, summarized mechanisms regulating food mitigation strategies, analyzed limitations current research prospected future research. combine receptors for (RAGE) induce oxidative stress, inflammation allergic signaling pathways. can affect allergen epitopes conformation regulate intestinal flora non-receptor-dependent manner, as well barrier Th1/Th2 immune balance through receptor-dependent pathways allergy. Currently, approaches reduce AGEs-induced mainly depended improving processing methods (e.g., low temperature, short time, pH non-thermal methods), natural inhibitors RAGE inhibitors. elucidates influences which provide novel insights into reducing induced AGEs.

Язык: Английский

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