Prevalence of Vancomycin-Resistant Van A and Van B Genes in ESKAPE Gram-Positive Bacteria Isolated from Hospitalized Patients in Mashhad, Iran DOI
Saeideh Hamzeh, Shahla Hosseini, Tohid Javaheri

и другие.

Research in Biotechnology and Environmental Science, Год журнала: 2024, Номер 3(4), С. 59 - 65

Опубликована: Дек. 12, 2024

Introduction: The ESKAPE group, comprising Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterococcus faecium, is known for its role in hospital-acquired infections growing resistance to antimicrobial agents. This complicates treatment options, particularly with last-resort antibiotics, such as vancomycin. study aims determine the prevalence of vancomycin-resistant genes (Van A Van B) aureus species isolated by polymerase chain reaction (PCR) method from hospitalized patients Mashhad, Iran. Materials Methods: total 1000 clinical samples were collected over six months four hospitals included blood, urine, wound swabs, respiratory secretions. isolates identified through standard microbiological tests. Vancomycin susceptibility was assessed using E-test method. presence determined PCR Results: Out a 98 bacterial isolates, 77 21 species. Among 15 faecium 6 faecalis. detected 7 total, these harboring gene 1 carrying B gene. Conclusion: reveals 40% 1.3% prevalences vancomycin respectively. These findings underscore critical need vigilant antibiotic stewardship implementation appropriate strategies effectively manage caused resistant pathogens.

Язык: Английский

A systematic review of potentially toxic elements (PTEs) in river sediments from China: evaluation of associated non-dietary health risks DOI
Yadolah Fakhri, Intissar Limam, Marzieh Kamali

и другие.

Environmental Monitoring and Assessment, Год журнала: 2025, Номер 197(3)

Опубликована: Фев. 11, 2025

Язык: Английский

Процитировано

0

Enhancing MRI diagnosis of myocarditis using deep learning and generative adversarial networks DOI Open Access
Honglian Gui, Na Zhang

Applied Mathematics and Nonlinear Sciences, Год журнала: 2025, Номер 10(1)

Опубликована: Янв. 1, 2025

Abstract In this paper, in order to enhance the MRI diagnosis of myocarditis, a generative adversarial network (GAN)-based diagnostic model for myocarditis is constructed paper. The images provided by hospital were used as data source study, and image format was transformed into NII file saving using Python tool, which uniformly cropped 480×768 pixels, stored form datasets, divided dataset A (the MRI-weighted dataset) B myocarditis). ResNet-34 U-Net generator discriminator, respectively, address problem difficulty training GAN networks, BN layer added between convolutional activation function construction finally completed. Determine loss function, select quantitative evaluation indexes (MAE, RMSE, PSNR, SSIM PCC), set control (CNN, RNN, LSTM, GRU), validate analyze discriminator after 400 iterations training, value both almost 0. paper’s genus pig are higher than other four models. summary, has facilitating effect on myocarditis.

Язык: Английский

Процитировано

0

Optimized Feature Selection and Deep Neural Networks to Improve Heart Disease Prediction DOI

Tan Chang-ming,

Zhe Yuan, Feng Xu

и другие.

Deleted Journal, Год журнала: 2025, Номер unknown

Опубликована: Апрель 16, 2025

Heart disease remains a significant health threat due to its high mortality rate and increasing prevalence. Early prediction using basic physical markers from routine exams is crucial for timely diagnosis intervention. However, manual analysis of large datasets can be labor-intensive error-prone. Our goal rapidly reliably anticipate cardiac variety body signs. This research presents unique model heart prediction. We provide system predicting that blends the deep convolutional neural network with feature selection technique based on LinearSVC. integrated method selects subset characteristics are strongly linked disease. feed these features into conventual we constructed. Also improve speed predictor avoid gradient varnishing or explosion, network's hyperparameters were tuned random search algorithm. The proposed was evaluated UCI MIT datasets. number indicators, such as accuracy, recall, precision, F1 score. results demonstrate our attains accuracy rates 98.16%, 98.2%, 95.38%, 97.84% in dataset, an average MCC score 90%. These affirm efficacy reliability predict

Язык: Английский

Процитировано

0

The concentration and prevalence of aflatoxins and ochratoxin A in imported rice ( Oryza sativa ) samples from Iranian market: a probabilistic dietary risk assessment DOI

Masoud Memar,

Zahra Esfandiari,

Mehrdad Ahmadi

и другие.

International Journal of Environmental & Analytical Chemistry, Год журнала: 2024, Номер unknown, С. 1 - 18

Опубликована: Ноя. 13, 2024

This investigation aimed to measure the concentrations of total aflatoxin (AFT), B1 (AFB1), and ochratoxin A (OTA) in imported rice samples Iran conduct a probabilistic health risk assessment for consumers. Three thousand seven hundred fifty-one were randomly collected from March 2022 April 2024. The AFT, AFB1, OTA analysed using high-performance liquid chromatography with flame ionisation detector (HPLC-FID) an ultraviolet (HPLC-UV). ranking mycotoxins based on mean concentration was as follows: AFT (3.996 ± 6.925 µg/kg) > AFB1 (2.648 5.746 (0.088 0.847 µg/kg). prevalence these found be present 897 out 3,710 (24.18%), 657 (17.52%), 40 (1.07%). Significant correlations observed between (C: 0.96, p-value < 0.001), 0.28, 0.15, 0.001). 95th percentile Margin Exposure (MOE) adult child consumers 0.930 0.270, respectively, while Hazard Quotient (HQ) adults children 0.030 0.100, respectively. estimated cancer percentages 22.220 43.500 children. Overall, consuming containing does not pose significant non-carcinogenic consumers' health. However, carcinogenic is higher than other countries. Therefore, it recommended that more effective continuous monitoring programmes implemented ensure quality rice.

Язык: Английский

Процитировано

1

Prevalence of Vancomycin-Resistant Van A and Van B Genes in ESKAPE Gram-Positive Bacteria Isolated from Hospitalized Patients in Mashhad, Iran DOI
Saeideh Hamzeh, Shahla Hosseini, Tohid Javaheri

и другие.

Research in Biotechnology and Environmental Science, Год журнала: 2024, Номер 3(4), С. 59 - 65

Опубликована: Дек. 12, 2024

Introduction: The ESKAPE group, comprising Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterococcus faecium, is known for its role in hospital-acquired infections growing resistance to antimicrobial agents. This complicates treatment options, particularly with last-resort antibiotics, such as vancomycin. study aims determine the prevalence of vancomycin-resistant genes (Van A Van B) aureus species isolated by polymerase chain reaction (PCR) method from hospitalized patients Mashhad, Iran. Materials Methods: total 1000 clinical samples were collected over six months four hospitals included blood, urine, wound swabs, respiratory secretions. isolates identified through standard microbiological tests. Vancomycin susceptibility was assessed using E-test method. presence determined PCR Results: Out a 98 bacterial isolates, 77 21 species. Among 15 faecium 6 faecalis. detected 7 total, these harboring gene 1 carrying B gene. Conclusion: reveals 40% 1.3% prevalences vancomycin respectively. These findings underscore critical need vigilant antibiotic stewardship implementation appropriate strategies effectively manage caused resistant pathogens.

Язык: Английский

Процитировано

0