Who is missed in a community-based survey: Assessment and implications of biases due to incomplete sampling frame in a community-based serosurvey, Choma and Ndola Districts, Zambia, 2022 DOI Creative Commons
Natalya Kostandova, Simon Mutembo, Christine Prosperi

и другие.

PLOS Global Public Health, Год журнала: 2024, Номер 4(4), С. e0003072 - e0003072

Опубликована: Апрель 29, 2024

Community-based serological studies are increasingly relied upon to measure disease burden, identify population immunity gaps, and guide control elimination strategies; however, there is little understanding of the potential for impact sampling biases on outcomes interest. As part efforts quantify measles gaps in Zambia, a community-based survey using stratified multi-stage cluster approach was conducted Ndola Choma districts May—June 2022, enrolling 1245 individuals. We carried out follow-up study among individuals missed from frame serosurvey July—August 672 assessed by i) estimating differences characteristics households included excluded (77% vs 23% households) ii) evaluating magnitude these make healthcare-seeking behavior, vaccination coverage, seroprevalence. found that were 20% smaller 25% less likely have children. Missed resided wealthy households, had different distributions sex occupation, more seek care at health facilities. Despite differences, simulating which resulted than 5% estimated bias outcomes. Although upheld as gold standard design assessing underlying community characteristics, findings underscore fact can results even well-conducted surveys. Results should be interpreted context methodology challenges faced during implementation, include shortcomings establishing accurate up-to-date frames. Failure account may result biased estimates detrimental effects decision-making.

Язык: Английский

Detection of IgG antibodies against the receptor binding domain of the spike protein and nucleocapsid of SARS-CoV-2 at university students from Southern Mexico: a cross-sectional study DOI Creative Commons

Jesús Adolfo Bailón-Cuenca,

Karen Cortés-Sarabia, José Legorreta-Soberanis

и другие.

BMC Infectious Diseases, Год журнала: 2024, Номер 24(1)

Опубликована: Июнь 12, 2024

Abstract Background Natural infection and vaccination against SARS-CoV-2 is associated with the development of immunity structural proteins virus. Specifically, two most immunogenic are S (spike) N (nucleocapsid) proteins. Seroprevalence studies performed in university students provide information to estimate number infected patients (symptomatic or asymptomatic) generate knowledge about viral spread, vaccine efficacy, epidemiological control. Which, aim this study was evaluate IgG antibodies at from Southern Mexico. Methods A total 1418 serum samples were collected eighteen work centers Autonomous University Guerrero. Antibodies detected by Indirect ELISA using as antigen peptides derived Results We reported a seroprevalence 39.9% anti-S/N (positive both antigens), 14.1% anti-S 0.5% anti-N. The highest Costa Grande, Acapulco Centro. age, COVID-19, contact patients, vaccination. Conclusion could play an essential role disseminating SARS-CoV-2. 54.5% proteins, which be due high population rate cultural resistance safety measures COVID-19 different regions state.

Язык: Английский

Процитировано

0
Seroprevalence of SARS-CoV-2 IgG antibodies among rural children aged 6-14 years in a selected block of West Bengal, India DOI Creative Commons
Vineeta Shukla, Vivek V. Shukla, Mausumi Basu

и другие.

IMC Journal of Medical Science, Год журнала: 2024, Номер unknown, С. 1 - 8

Опубликована: Июль 11, 2024

Background and objectives: Children comprised a significant part of the population during second third waves COVID-19 pandemic. The objectives this study were to estimate seroprevalence IgG antibody among children aged 6 14 years determine, if any, factors associated with seropositivity. Methods: This cross-sectional was conducted in selected block West Bengal, India over period 1 year (April 2022-March 2023) children. Thirty villages by cluster sampling technique. IgM/IgG Rapid Antibody Test Kit (ICMR approved) used for detection SARS-CoV-2 antibodies. Data analyzed appropriate statistical tests. Results: Total 600 enrolled study.SARS-CoV-2 positive 57.2% seropositivity rate (91.8%) significantly (p<0.001) high age group 12 years. Seropositivity not different between male female (46.4% vs. 53.6%; p>0.05). Conclusion: SARS-COV-2 proportion residing rural areas indicating asymptomatic coronavirus infections population. Socio-demographic such as higher father’s education July 2024; Vol. 18(2):010. DOI:https://doi.org/10.55010/imcjms.18.022 *Correspondence: Vineeta Shukla, Department Community Medicine, Infectious Diseases Beliaghata General Hospital, Kolkata, India. Email: [email protected]

Язык: Английский

Процитировано

0
Assessment of Antibody Titers after 6 Months of Vaccination against SARS-COV-2 in Patients with CKD Stage 4, 5 and CKD 5d DOI Open Access

Dr. Md Farucul Hasan,

Prof. Dr. Md. Nazrul Islam,

Abu Saleh Ahmed

и другие.

Saudi Journal of Medical and Pharmaceutical Sciences, Год журнала: 2024, Номер 10(07), С. 436 - 446

Опубликована: Июль 8, 2024

Background: Since the pandemic of COVID-19 started from December 2019, remarkable numbers infections and deaths associated with have been recorded worldwide. Chronic kidney disease patients are particularly at high risk due to impairments in innate adaptive immune systems. Adequate humoral (antibody) cellular (T cell-driven) immunity required minimize pathogen entry promote clearance enable infection control. Vaccination can generate against this specific pathogen. prevention through successful vaccination is therefore paramount chronic population. But efficacy diminished these because premature ageing system systemic low- grade inflammation main causes alteration patients. Therefore, it urgently necessary establish a different strategy for dialysis patient terms dose administration time. Aims: This study aimed assessment antibody titers after SARS-COV-2 stage 4, 5 on conservative management maintenance haemodialysis. Methods: prospective observational comparative was conducted Nephrology department Dhaka Medical College Hospital. Selectionof done by purposive sampling according inclusion exclusion criteria. Total 135 distributed three groups: 45 (CKD) management, haemodialysis (MHD) healthy controls were approached who receiving vaccination. Demographic, clinical laboratory data collected initially. At first pre sample or 1st taken measurement. Then participants all groups given 2 doses MODERNA vaccine containing 100 µg 0.5 ml each 28 days apart. 14 2nd samples taken, 3rd Study populations subdivided into two titer; seropositive- positive response before seronegative- negative They also divided quantitive response; response- values ≥10 DU/mL Negative <10 negative. Result: Seroconversion rate around 20% among vaccination, 90.04% had CKD group whereas MHD 84.82% responded control 100%. Immune 100% but concentration differs significantly groups. Responders comparatively younger normal BMI. Conclusion: Haemodialysis as well showed favorable profoundly lower early response, which decreased substantially during follow-up.

Язык: Английский

Процитировано

0
Recent advances in metal sulfide nanomaterials for antimicrobial activity and disinfection self-cleaning DOI
Nibedita Nath,

Subhendu Chakroborty,

Suresh Babu Naidu Krishna

и другие.

Elsevier eBooks, Год журнала: 2024, Номер unknown, С. 325 - 342

Опубликована: Ноя. 22, 2024

Язык: Английский

Процитировано

0
Who is missed in a community-based survey: Assessment and implications of biases due to incomplete sampling frame in a community-based serosurvey, Choma and Ndola Districts, Zambia, 2022 DOI Creative Commons
Natalya Kostandova, Simon Mutembo, Christine Prosperi

и другие.

PLOS Global Public Health, Год журнала: 2024, Номер 4(4), С. e0003072 - e0003072

Опубликована: Апрель 29, 2024

Community-based serological studies are increasingly relied upon to measure disease burden, identify population immunity gaps, and guide control elimination strategies; however, there is little understanding of the potential for impact sampling biases on outcomes interest. As part efforts quantify measles gaps in Zambia, a community-based survey using stratified multi-stage cluster approach was conducted Ndola Choma districts May—June 2022, enrolling 1245 individuals. We carried out follow-up study among individuals missed from frame serosurvey July—August 672 assessed by i) estimating differences characteristics households included excluded (77% vs 23% households) ii) evaluating magnitude these make healthcare-seeking behavior, vaccination coverage, seroprevalence. found that were 20% smaller 25% less likely have children. Missed resided wealthy households, had different distributions sex occupation, more seek care at health facilities. Despite differences, simulating which resulted than 5% estimated bias outcomes. Although upheld as gold standard design assessing underlying community characteristics, findings underscore fact can results even well-conducted surveys. Results should be interpreted context methodology challenges faced during implementation, include shortcomings establishing accurate up-to-date frames. Failure account may result biased estimates detrimental effects decision-making.

Язык: Английский

Процитировано

0