Metal-Organic Frameworks: Performance, Fabrication, and Applications in Biosensors DOI
You Wu

Transactions on Materials Biotechnology and Life Sciences, Год журнала: 2024, Номер 7, С. 289 - 292

Опубликована: Дек. 24, 2024

Biosensors serve as key detection tools in many fields, such clinical diagnosis, environmental monitoring and food safety. Although breakthroughs have been achieved the field of sensor technology, related issues sensitivity, specificity stability remain unresolved. Recent academic research has highlighted significant prospects metal-organic frameworks (MOFs) potential solutions to these problems. The MOFs, which are composed organic ligands metal ions, high surface area, adjustable pore size excellent chemical versatility. By optimizing characteristics, sensitivity selectivity biosensors improved, thereby improving their performance. This study analyzes extensive on MOF-based biosensors. paper emphasizes synthesis methods, functionalization strategies, applications. Specifically, application here is mainly biomarkers cancer cardiovascular diseases. role MOFs-based cell tissue imaging discussed well. goal this explain latest results define areas exploration for subsequent scientific works. work would contribute improve biosensing technology.

Язык: Английский

The Role of NT-proBNP Levels in the Diagnosis of Hypertensive Heart Disease DOI Creative Commons
Angeliki Mouzarou,

Nikoleta Hadjigeorgiou,

Despo Melanarkiti

и другие.

Diagnostics, Год журнала: 2025, Номер 15(1), С. 113 - 113

Опубликована: Янв. 6, 2025

Hypertension is a major risk factor of various cardiac complications, including hypertensive heart disease (HHD). This condition can lead to number structural and functional changes in the heart, such as left ventricular hypertrophy, diastolic dysfunction, and, eventually, systolic dysfunction. In management disease, early diagnosis appropriate treatment are crucial for preventing progression congestive failure. One potential diagnostic marker that has gained attention recent years N-terminal pro-brain natriuretic peptide (NT-proBNP). The peptides, brain (BNP) its inactive fragment, secreted by myocardium response increased wall stress volume overload. patients with NT-proBNP levels may reflect occurring result chronic pressure Several studies have investigated utility disease. be useful adjunct particularly assessment dysfunction hypertrophy. review paper explores role

Язык: Английский

Процитировано

0
Integrative bioinformatic analysis of prognostic biomarkers in heart failure: Insights from clinical trials DOI Open Access
José Mesquita Bastos,

Noemi Scala,

Luís Perpétuo

и другие.

European Journal of Clinical Investigation, Год журнала: 2025, Номер unknown

Опубликована: Фев. 16, 2025

Abstract Background Heart failure (HF) remains a major cause of morbidity and mortality worldwide. Therefore, there is need to identify robust biomarkers improve early diagnosis, stratify disease severity predict outcomes. Biomarkers such as galectin‐3 (Gal‐3), TIMP‐1, BNP, NT‐proBNP, CysC, CA125, ST2 MMP9 have shown the potential reflect pathophysiology HF. Despite their clinical potential, integration into routine practice still limited. The use bioinformatics may help uncover critical associations between these progression HF, providing opportunities for personalized management. Methods Following PRISMA guidelines, systematic review studies was performed using databases with time constraints. proteins associated HF were identified diagnostic prognostic roles analysed. Results study emphasizes that (Gal‐3) TIMP‐1 serve key indicators fibrosis inflammation, while BNP NT‐proBNP are reliable markers cardiac stress. Cystatin C (CysC) reflects renal dysfunction, CA125 correlates strongly venous congestion. In addition, provide valuable insights inflammation tissue remodelling processes. These consistently elevated in patients emphasizing role detecting systemic manifestations disease. Conclusion Our results emphasize importance including Gal‐3, diagnosis treatment Their upregulation complex pathophysiological processes supports setting accuracy, precision therapeutic strategies.

Язык: Английский

Процитировано

0
Recent advances in MOF-modified electrochemical sensor for point-of-care detecting cardiac biomarkers DOI
Mohamed Ahmed, Jingyi Bai, Lingxue Kong

и другие.

TrAC Trends in Analytical Chemistry, Год журнала: 2025, Номер unknown, С. 118277 - 118277

Опубликована: Апрель 1, 2025

Язык: Английский

Процитировано

0
The CRISPR/Cas13a-assisted electrochemiluminescence sensing device combined with entropy-driven and hybrid chain reaction nucleic acid amplification techniques for ultra-sensitive analysis of brain natriuretic peptide DOI
Haixiang Li,

Shijie Lian,

Zhiwei Zhang

и другие.

Talanta, Год журнала: 2025, Номер unknown, С. 128310 - 128310

Опубликована: Май 1, 2025

Язык: Английский

Процитировано

0
Enhanced Electrochemiluminescence Sensing of Brain Natriuretic Peptide (BNP) using Copper Nanocluster and Luminol-H2O2 based System in Heart Failure Diagnosis DOI

B. K. Arathy,

Merin K. Abraham,

Geneva Indongo

и другие.

Talanta, Год журнала: 2025, Номер 295, С. 128362 - 128362

Опубликована: Май 21, 2025

Язык: Английский

Процитировано

0
Prognostic Utility of N-terminal Pro-B-type Natriuretic Peptide (NT-proBNP) for Predicting Hospital Readmissions in Patients With Heart Failure: A Systematic Review of Clinical Evidence DOI Open Access
Hassaan Arshad,

Fnu Laraib,

FNU Nikeeta

и другие.

Cureus, Год журнала: 2025, Номер unknown

Опубликована: Июнь 2, 2025

Язык: Английский

Процитировано

0
DISPOSITIVOS MÉDICOS CONECTADOS. AVANCES EN MONITOREO Y DIAGNÓSTICO DOI Creative Commons
Edwin Gerardo Acuña Acuña, Felipe Ángel Álvarez Salgado, Silvia Munárriz Delgado

и другие.

New Trends in Qualitative Research, Год журнала: 2024, Номер 20(3), С. e1053 - e1053

Опубликована: Авг. 26, 2024

Introducción: Este estudio examina la revolución tecnológica en el ámbito de los dispositivos médicos conectados, que están redefiniendo monitoreo, diagnóstico y tratamiento enfermedades. Se analiza cómo integración tecnologías avanzadas está impulsando atención médica personalizada a distancia. Objetivos: Evaluar avances conectados su impacto mejora del monitoreo investiga estas cambiando dinámica cuáles son desafíos oportunidades asociados. Metodología: utiliza un enfoque cualitativo, vinculando preguntas investigación con teorías resultados. El se basa análisis wearables sistemas implantables, combinando revisión literatura entrevistas expertos datos. metodológico permite una comprensión profunda interacción entre tecnología práctica médica. Resultados: Los hallazgos muestran ofrecen significativas ventajas términos precisión eficiencia, permitiendo seguimiento tiempo real mejor toma decisiones clínicas. identifican retos técnicos, éticos regulatorios, pero también destacan soluciones innovadoras para superarlos. Conclusiones: La subraya importancia cualitativo conectados. resultados enfatizan necesidad marco robusto evaluar tanto tecnológicos como contribuye transformando médica, enfatizando abordajes integrados multidisciplinarios maximizar sus beneficios minimizar riesgos.

Процитировано

0
Metal-Organic Frameworks: Performance, Fabrication, and Applications in Biosensors DOI
You Wu

Transactions on Materials Biotechnology and Life Sciences, Год журнала: 2024, Номер 7, С. 289 - 292

Опубликована: Дек. 24, 2024

Biosensors serve as key detection tools in many fields, such clinical diagnosis, environmental monitoring and food safety. Although breakthroughs have been achieved the field of sensor technology, related issues sensitivity, specificity stability remain unresolved. Recent academic research has highlighted significant prospects metal-organic frameworks (MOFs) potential solutions to these problems. The MOFs, which are composed organic ligands metal ions, high surface area, adjustable pore size excellent chemical versatility. By optimizing characteristics, sensitivity selectivity biosensors improved, thereby improving their performance. This study analyzes extensive on MOF-based biosensors. paper emphasizes synthesis methods, functionalization strategies, applications. Specifically, application here is mainly biomarkers cancer cardiovascular diseases. role MOFs-based cell tissue imaging discussed well. goal this explain latest results define areas exploration for subsequent scientific works. work would contribute improve biosensing technology.

Язык: Английский

Процитировано

0