Innovations in Neurophysiology and Its Role in Neuropsychiatry DOI
Görsev Yener,

Didem Öz

Nöro Psikiyatri Arşivi, Год журнала: 2022, Номер unknown

Опубликована: Янв. 1, 2022

Many structural and functional tests are used to explore the nature of neurodevelopmental neurodegenerative diseases. Cognitive involvement has become more remarkable in many neurological psychiatric This condition evoked a paradigm shift, today disorders addressed from neuroscientific perspective, including silent symptoms. The spatial resolution studies is lacking combined with unique temporal EEG methods. In our current clinical practice, does not have definitive diagnostic value disorders, but it helps make correct diagnosis by excluding other However, use for research purposes promising both groups. this review; there up-to-date information on electrophysiological examinations diseases, especially Alzheimer's disease, Parkinson's Frontotemporal dementia, such as schizophrenia, mood attention deficit hyperactivity disorder, obsessive-compulsive define point we reached journey understand these disorders.

Язык: Английский

State-of-the-art imaging of neuromodulatory subcortical systems in aging and Alzheimer’s disease: Challenges and opportunities DOI Creative Commons
Nina Engels, Elouise A. Koops, Prokopis C. Prokopiou

и другие.

Neuroscience & Biobehavioral Reviews, Год журнала: 2022, Номер 144, С. 104998 - 104998

Опубликована: Дек. 13, 2022

Язык: Английский

Процитировано

27

Parallel electrophysiological abnormalities due to COVID‐19 infection and to Alzheimer's disease and related dementia DOI Creative Commons
Yang Jiang, Jennifer Watling Neal, Pradoldej Sompol

и другие.

Alzheimer s & Dementia, Год журнала: 2024, Номер unknown

Опубликована: Авг. 29, 2024

Many coronavirus disease 2019 (COVID-19) positive individuals exhibit abnormal electroencephalographic (EEG) activity reflecting "brain fog" and mild cognitive impairments even months after the acute phase of infection. Resting-state EEG abnormalities include slowing (reduced alpha rhythm; increased slow waves) epileptiform activity. An expert panel conducted a systematic review to present compelling evidence that deficits due COVID-19 Alzheimer's related dementia (ADRD) are driven by overlapping pathologies neurophysiological abnormalities. seen in patients resemble those observed early stages neurodegenerative diseases, particularly ADRD. It is proposed similar Long COVID ADRD parallel neuroinflammation, astrocyte reactivity, hypoxia, neurovascular injury. These underpinning decline can be detected routine exams. Future research will explore value monitoring for predicting long-term outcomes efficacy therapeutic interventions. HIGHLIGHTS: Abnormal intrinsic electrophysiological brain activity, such as EEG, reduced wave, characteristic findings patients. have potential neural biomarkers identify neurological complications at stage disease, assist clinical assessment, assess risk Similar typically with impairments, Evidence presented supports idea resulting, least part, from neuroinflammatory mechanisms reactivity. Identifying common biological highlight critical underlying disorders decline. elucidates questions regarding impairment not yet been adequately investigated.

Язык: Английский

Процитировано

5

The Dark Side of Alzheimer’s Disease: Neglected Physiological Biomarkers of Brain Hyperexcitability and Abnormal Consciousness Level DOI Open Access
Claudio Babiloni

Journal of Alzheimer s Disease, Год журнала: 2022, Номер 88(3), С. 801 - 807

Опубликована: Июнь 24, 2022

The National Institute of Aging and Alzheimer's Association have recently proposed a framework for the neurobiological diagnosis disease (AD) research applications [1].That states that AD can be based on biomarkers derived from in vivo measurement amyloidosis ('A'), tauopathy ('T'), neurodegeneration ('N') brain patients with AD, regardless clinical manifestations continuum subjective cognitive complaint, mild impairment (MCI), mild, moderate, or severe degree dementia [1].Specifically, measured by laboratory analysis cerebrospinal fluid positron emission tomography (PET) mapping, while probed structural magnetic resonance imaging fluorodeoxyglucose PET

Язык: Английский

Процитировано

15

Electrophysiological correlates of visual short-term memory Binding deficits in community-dwelling seniors at risk of dementia DOI Creative Commons
Rodrigo A. Gonzalez‐Montealegre, Alfredis González‐Hernández, Jasmín Bonilla-Santos

и другие.

Clinical Neurophysiology, Год журнала: 2025, Номер 171, С. 227 - 239

Опубликована: Янв. 25, 2025

Язык: Английский

Процитировано

0

Comparing levetiracetam and zonisamide effects on rivastigmine anti-Alzheimer’s activity in aluminum chloride-induced Alzheimer’s-like disease in rats: Impact on α7 nicotinic acetylcholine receptors and amyloid β DOI

Raafat A. Abdel-Aal,

Fatma Y. Meligy,

Nashwa Maghraby

и другие.

Brain Research, Год журнала: 2025, Номер unknown, С. 149573 - 149573

Опубликована: Март 1, 2025

Язык: Английский

Процитировано

0

Transcranial alternating current stimulation in affecting cognitive impairment in psychiatric disorders: a review DOI Creative Commons

Nina Biačková,

Andrea Adamová,

Monika Klírová

и другие.

European Archives of Psychiatry and Clinical Neuroscience, Год журнала: 2023, Номер 274(4), С. 803 - 826

Опубликована: Сен. 8, 2023

Transcranial alternating current stimulation (tACS) is a non-invasive brain method that, through its manipulation of endogenous oscillations, can affect cognition in healthy adults. Given the fact that both oscillations and are impaired various psychiatric diagnoses, tACS might represent suitable intervention. We conducted search Pubmed Web Science databases reviewed 27 studies where used diagnoses change evaluated. TACS safe well-tolerated intervention method, for multiple-sessions protocols. It be administered at home, individualized according to patient''s anatomical functional characteristics, or as marker disease progression. The results varying across applied protocols, with some protocols showing long-term effect. However, overall number small great variety parameters, such electrode montage frequency. Precise mechanisms interaction pathophysiological processes only partially described need further research. Currently, seems feasible alleviate cognitive impairment patients; however, more robust confirmation efficacy potential needed introduce it into clinical practise.

Язык: Английский

Процитировано

6

Age-Related Aspects of Sex Differences in Event-Related Brain Oscillatory Responses: A Turkish Study DOI Creative Commons
Görsev Yener, İlayda Kıyı, Seren Düzenli‐Öztürk

и другие.

Brain Sciences, Год журнала: 2024, Номер 14(6), С. 567 - 567

Опубликована: Июнь 3, 2024

Earlier research has suggested gender differences in event-related potentials/oscillations (ERPs/EROs). Yet, the alteration oscillations (EROs) delta and theta frequency bands have not been explored between genders across three age groups of adulthood, i.e., 18–50, 51–65, >65 years. Data from 155 healthy elderly participants who underwent a neurological examination, comprehensive neuropsychological assessment (including attention, memory, executive function, language, visuospatial skills), magnetic resonance imaging (MRI) past studies were used. The ERO powers compared correlational analyses among power, age, tests performed. results indicated that females displayed higher responses than males frontal, central, parietal regions but occipital location 18 50 years adulthood. declining power EROs women reached men after while was more stable men. Our imply cohorts must be recruited at specified ranges genders, clinical trials using neurophysiological biomarkers as an intervention endpoint should take into account future.

Язык: Английский

Процитировано

1

A distributed theta network of error generation and processing in aging DOI
Vasil Kolev, Michael Falkenstein, Juliana Yordanova

и другие.

Cognitive Neurodynamics, Год журнала: 2023, Номер 18(2), С. 447 - 459

Опубликована: Ноя. 16, 2023

Язык: Английский

Процитировано

3

EEG, ERPs, and EROs in patients with cognitive deficits due to progressive neurodegenerative diseases: The dark side of the precision medicine DOI Open Access
Claudio Babiloni, Bahar Güntekin

International Journal of Psychophysiology, Год журнала: 2023, Номер 190, С. 56 - 59

Опубликована: Июнь 10, 2023

Язык: Английский

Процитировано

1

Aging alters functional connectivity of motor theta networks during sensorimotor reactions DOI Creative Commons
Juliana Yordanova, Michael Falkenstein, Vasil Kolev

и другие.

Clinical Neurophysiology, Год журнала: 2024, Номер 159, С. 97 - 109

Опубликована: Фев. 27, 2024

Both cognitive and primary motor networks alter with advancing age in humans. The activated response to external environmental stimuli supported by theta oscillations remain less well explored. present study aimed characterize the effects of aging on functional connectivity response-related during sensorimotor tasks. Electroencephalographic signals were recorded young middle-to-older adults three tasks performed two modalities, auditory visual: a simple reaction task, Go-NoGo choice-reaction task. Response-related computed. phase-locking value (PLV) was used analyze spatial synchronization control networks. Performance overall preserved older adults. Independently associated reorganized contra-lateral cortex. In younger adults, it synchronized regions (intra-hemispheric premotor/frontal medial frontal). only intra-hemispheric regions. Motor manifest decoupling between response-generating cortex regions, which not modulated task variables. performance suggests that increased within network is an excessive reliance feedback movement execution compensating for deficient regulation reactions. New evidence provided reorganization reactions already at transition from middle old age.

Язык: Английский

Процитировано

0