Electrospun chitosan//ethylcellulose-vitamin E//ethylcellulose-curcumin tri-chamber eccentric Janus nanofibers for a joint antibacterial and antioxidant performance

International Journal of Biological Macromolecules, Год журнала: 2024, Номер 281, С. 135753 - 135753

Опубликована: Окт. 17, 2024

Язык: Английский

---

Reverse Gradient Distributions of Drug and Polymer Molecules within Electrospun Core–Shell Nanofibers for Sustained Release

International Journal of Molecular Sciences, Год журнала: 2024, Номер 25(17), С. 9524 - 9524

Опубликована: Сен. 1, 2024

Core–shell nanostructures are powerful platforms for the development of novel nanoscale drug delivery systems with sustained release profiles. Coaxial electrospinning is facile and convenient creating medicated core–shell elaborate designs which sustained-release behaviors molecules can be intentionally adjusted. With resveratrol (RES) as a model poorly water-soluble cellulose acetate (CA) PVP polymeric carriers, brand-new electrospun nanostructure was fabricated in this study. The guest RES host CA were designed to have reverse gradient distribution within nanostructures. Scanning electron microscope transmission evaluations verified that these nanofibers had linear morphologies, without beads or spindles, an obvious double-chamber structure. X-ray diffraction patterns Fourier transform infrared spectroscopic results indicated involved components highly compatible presented amorphous molecular state. In vitro dissolution tests new structures able prevent initial burst release, extend continuous-release time period, reduce negative tailing-off effect, thus ensuring better profile than traditional blended drug-loaded nanofibers. mechanism underlying influence structure RES/CA on proposed. Based proof-of-concept demonstration, series advanced functional nanomaterials similarly developed based distributions multi-chamber

Язык: Английский

---

Synergistic Effects of Radical Distributions of Soluble and Insoluble Polymers within Electrospun Nanofibers for an Extending Release of Ferulic Acid

Polymers, Год журнала: 2024, Номер 16(18), С. 2614 - 2614

Опубликована: Сен. 15, 2024

Polymeric composites for manipulating the sustained release of an encapsulated active ingredient are highly sought after many practical applications; particularly, water-insoluble polymers and core–shell structures frequently explored to manipulate behaviors drug molecules over extended time period. In this study, electrospun nanostructures were utilized develop a brand-new strategy tailor spatial distributions both insoluble polymer (ethylcellulose, EC) soluble (polyvinylpyrrolidone, PVP) within nanofibers, thereby extended-release loaded ingredient, ferulic acid (FA). Scanning electron microscopy transmission assessments revealed that all prepared nanofibers had linear morphology without beads or spindles, those from coaxial processes obvious structure. X-ray diffraction attenuated total reflectance Fourier transform infrared spectroscopic tests confirmed FA fine compatibility with EC PVP, presented in amorphous state. vitro dissolution indicated radical (decreasing shell core) PVP (increasing able play their important role elaborately. On one hand, F3 advantages homogeneous composite F1 higher content solutions inhibit initial burst provide longer period release. other F2 core negative tailing-off The key element was water permeation rates, controlled by ratios polymers. new based on structure paves way developing wide variety polymeric heterogeneous realizing desired functional performances.

Язык: Английский

---

Synergistic improvements of properties of cellulose acetate based curcumin@TiO2 nanofibers via triaxial electrospinning

Chemical Engineering Journal, Год журнала: 2025, Номер 506, С. 160117 - 160117

Опубликована: Янв. 1, 2025

Язык: Английский

---

Harnessing Electrospun Nanofibers for Comprehensive Oral Disease Management: Current Trends and Future Perspectives

Journal of Drug Delivery Science and Technology, Год журнала: 2025, Номер 106, С. 106681 - 106681

Опубликована: Фев. 7, 2025

Язык: Английский

---

Challenges Associated with the Production of Nanofibers

Processes, Год журнала: 2024, Номер 12(10), С. 2100 - 2100

Опубликована: Сен. 27, 2024

Nanofibers, with their high surface area-to-volume ratio and unique physical properties, hold significant promise for a wide range of applications, including medical devices, filtration systems, packaging, electronics, advanced textiles. However, development commercialization are hindered by several key challenges hazards. The main issues production cost yield, voltage, clogging, toxic materials driven complex techniques, which limit adoption. Additionally, there environmental health concerns associated nanofiber disposal, necessitating the safer more sustainable processes materials. Addressing these requires continued innovation in science industrial practices, as well concerted effort to balance production, material, surrounding condition parameters. This study emphasizes hazards electrospinning, centrifugal spinning, solution blow electro-blown wet melt spinning. It also biopolymers recycling eco-friendly practices avoid harming environment human beings.

Язык: Английский

---

Light-Activated Nanofibers: Advances in Photo-Responsive Electrospun Polymer Technologies

Polymer-Plastics Technology and Materials, Год журнала: 2024, Номер 64(4), С. 397 - 438

Опубликована: Окт. 1, 2024

Язык: Английский

---

From nature to nanotech: Harnessing the power of electrospun polysaccharide-based nanofibers as sustainable packaging

International Journal of Biological Macromolecules, Год журнала: 2025, Номер 299, С. 140127 - 140127

Опубликована: Янв. 21, 2025

Язык: Английский

---

Cyclodextrin nanocarriers in Coordination Chemistry: Enhancing encapsulation and targeted delivery of 5-Fluorouracil for cancer treatment

Results in Chemistry, Год журнала: 2024, Номер 12, С. 101878 - 101878

Опубликована: Окт. 30, 2024

Язык: Английский

---

Wound dressings using electrospun nanofibers: mechanisms, applications, and future directions

European Polymer Journal, Год журнала: 2025, Номер unknown, С. 113900 - 113900

Опубликована: Март 1, 2025

Язык: Английский

---