Опубликована: Авг. 13, 2024
Язык: Английский
Опубликована: Авг. 13, 2024
Язык: Английский
Building and Environment, Год журнала: 2025, Номер unknown, С. 112727 - 112727
Опубликована: Фев. 1, 2025
Язык: Английский
Процитировано
0Biomedical Engineering / Biomedizinische Technik, Год журнала: 2025, Номер unknown
Опубликована: Май 5, 2025
Abstract Objectives Contaminated apparatus and surgical tools pose serious health risks. For such purpose, disinfection chambers are employed. However, these systems rely on mercury-based UV lamps which comes with various drawbacks. These limitations have driven interest in Ultraviolet-C Light Emitting Diode (UV-C LED) technology as a safer more efficient alternative. existing studies not thoroughly explored the impact of varying intensities pulse width modulation (PWM) efficacy. Methods To addess this, present study designed tested LED-based chamber by employing 4-W 275 nm Surface Mount Device (SMD) LEDs against frequently isolated bacteria. By following prior approach, irradiation time was alternated at 30-s intervals antibacterial efficacy assessed through parameters. Additionally, scanning electron microscopy (SEM) performed to examine morphological changes. Results indicated that reduction significantly influenced (p<0.05) PWM levels (60–100 %), achieving 2.05-log 10 1.54-log inactivation Escherichia coli Staphylococcus aureus, respectively, upon exposure 51.24 mJ/cm 2 under maximum settings. Moreover, complete cellular damage leading bleb protrusion cell-leakage confirmed disruption bacterial DNA. Conclusions In conclusion, UV-LEDs show great potential for disinfection, efficiency dosage.
Язык: Английский
Процитировано
0Опубликована: Авг. 13, 2024
Язык: Английский
Процитировано
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