PLoS ONE, Год журнала: 2025, Номер 20(1), С. e0314861 - e0314861

Опубликована: Янв. 30, 2025

Radiotherapy is the main treatment for patients with head and neck cancer (HNC) associated an increased risk of ischemic cerebrovascular events (ICVE). The purpose this cross-sectional study was to determine incidence ICVE carotid artery stenosis (CAS) in HNC who receive radiotherapy factors CAS. We enrolled 907 underwent between February 2011 June 2022 obtained information on their clinical tumor characteristics from records. Data atherosclerosis, medications used, were also collected. followed through end 2023 unless they died or lost follow-up. overall 1.98%, a cumulative 1.65% over 5 years. In did not have preexisting lesion, significant CAS 1.3% at 12 months, 2.2% 24 2.5% 36 months post-radiotherapy. most important new age >65 years (aHR = 2.60, p 0.008, 95% confidence Interval: 1.28–5.30), laryngeal 2.36, p<0.017, 1.01–5.55), total plaque score 1.38, p<0.001, 1.23–1.56). There increase stenosis, score, wall thickness all areas (p<0.001). found be lower Thai population than other populations. years, cancer, score. Changes detected early affected artery. Patients treated by should assessed undergo vascular surveillance during

Язык: Английский