Syndecans and glycosaminoglycans influence B-cell development and activation

EMBO Reports, Год журнала: 2025, Номер unknown

Опубликована: Март 28, 2025

Язык: Английский

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Quantifying the waning of humoral immunity

medRxiv (Cold Spring Harbor Laboratory), Год журнала: 2025, Номер unknown

Опубликована: Май 14, 2025

Abstract Immunological memory is a defining feature of immunity, yet surprisingly there no consensus on how to quantitatively describe antibody titers wane over time. A major problem that the slow waning requires collection data for decades post-infection or vaccination. Our analysis largest existing dataset shows power-law model describes better than other frequently used models. suggests: (i) Protective levels antibodies many vaccine/virus antigens may be maintained longer previously estimated. (ii) The rate protein toxoid vaccines such as tetanus similar those elicited by live virus infections. (iii) long-term can estimated from much shorter time-frame about 1-3 years following immunization, suggesting using could allow rapid estimation immunity new vaccines.

Язык: Английский

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Predicting plasma cell retention and loss over a lifetime

Immunity, Год журнала: 2024, Номер 57(3), С. 408 - 410

Опубликована: Март 1, 2024

Язык: Английский

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Plasma Cells: Antibody and Beyond

Elsevier eBooks, Год журнала: 2024, Номер unknown

Опубликована: Янв. 1, 2024

Язык: Английский

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