Infection Prevention in Practice, Год журнала: 2023, Номер 5(4), С. 100317 - 100317
Опубликована: Ноя. 14, 2023
Язык: Английский
Cureus, Год журнала: 2025, Номер unknown
Опубликована: Март 12, 2025
Background Antimicrobial resistance (AMR) is a growing global health concern, primarily driven by the irrational and excessive use of antimicrobials. Self-medication with antibiotics, often without medical prescription, contributes significantly to emergence resistant bacteria strains. This study aims assess patterns antimicrobial consumption its role in development antibiotic resistance. Aim objective The aim are evaluate prevalence, determinants, associated factors self-medication antimicrobials rural area Andaman Nicobar Islands. Materials methods A cross-sectional was conducted among 437 participants community. Data on socio-demographic characteristics, patterns, reasons for were collected using structured questionnaire. data analyzed SPSS version 26.0 (IBM Corp., Armonk, NY, US) associations between variables. Results found that 64.3% self-medicated antimicrobials, while 35.7% did not. most common sources determining dosage included pharmacists (27.8%), hospital staff (21.7%), personal experience (19.3%). significant proportion (65.4%) altered during course treatment, due symptom improvement (53.4%) or lack (25.1%). statistically association observed age (p = 0.024), gender 0.0095), religion 0.00), socio-economic status 0.01). Conclusion High rates coupled inappropriate usage contribute increasing burden Strengthening public awareness, implementing stricter regulations sales, promoting rational prescribing practices essential measures combat AMR.
Язык: Английский
Процитировано
0
Antimicrobial Resistance and Infection Control, Год журнала: 2025, Номер 14(1)
Опубликована: Апрель 5, 2025
Abstract Background Hospitals in low- and middle-income countries (LMIC) face context-specific challenges implementing antimicrobial stewardship (AMS) programmes. The Global Point Prevalence Survey (Global-PPS) project has established a network of hospitals across 90 countries, using point prevalence surveys to monitor use guide AMS activities. However, little is known about implementation these hospitals. Using qualitative research, we aim explore the process LMIC within Global-PPS factors influencing it, identify potential strategies, evaluate role this process. Methods A study was conducted semi-structured online interviews with healthcare workers (HCWs) involved network. Participants were selected combination convenience purposive sampling included clinicians, microbiologists, pharmacists, nurses. Interviews followed topic based on integrated checklist determinants practice (TICD Checklist). Transcripts analysed inductive deductive thematic analyses. Findings Twenty-two HCWs from 16 interviewed. different stages at time study, pre-implementation institutionalisation as part continuous quality improvement While provided valuable tool for education implementation, contextual barriers often hindered translation findings into targeted interventions. Four themes influenced “institutional support resource allocation”, “AMS team functioning, roles, expertise”, “adoption integration recommendations”, “data-driven decision-making” cross-cutting theme. Key competencies, multidisciplinary teams, sustainable funding leadership support, diagnostic capacity, reliable data inform We also identified various strategies employed by local teams enhance implementation. Conclusions This examines identifies key determinants. address through task shifting, engagement ownership. empirical evidence effectiveness limited, insights can future interventions studies Strengthening requires bridging gap between measurement action expanding research behaviour change.
Язык: Английский
Процитировано
0
Deleted Journal, Год журнала: 2025, Номер 22(1)
Опубликована: Май 10, 2025
Abstract The issue of antimicrobial resistance (AMR) is global significance, affecting both developed and underdeveloped nations. In the context low- middle-income countries (LMICs), in Africa other regions confronted with worsening health inequities such as inadequate healthcare resources infrastructure, a rising burden infectious diseases, adverse impact exacerbated. This narrative review delves into difficulties encountered tackling effects AMR, focusing specifically on LMICs Africa, where overlap climatic factors, socio-economic disparities, access to intensifies problem. themes that emerged from include need for infection prevention control strategies, adoption One Health approach combat surveillance monitoring. Several challenges were identified, including organizational governmental issues, absence leadership commitment. also emphasized public professional education professionals patients promote influence behavioral change patterns, central aspect AMR issues Africa. These initiatives should be tandem enhanced diagnostic capacity, effective surveillance, capacity building at all levels system. Sustaining stewardship programs presents considerable obstacles, ranging financial constraints lack political will coordinated efforts. When partners adequately address these by implementing sustainable solutions, can mitigate threat safeguard health, responsible use antimicrobials future generations.
Язык: Английский
Процитировано
0
Clinical and Preventive Medicine, Год журнала: 2025, Номер 3, С. 96 - 103
Опубликована: Март 20, 2025
Introduction. Antimicrobial stewardship (AMS) is considered a key strategy for preventing and addressing the problem of antimicrobial resistance. Most recent data on challenges in AMS implementation come from well-resourced hospitals high-income countries. It remains unclear whether findings these studies can be applied to resource-limited [3]. Aim. To examine identified by healthcare professionals implementing institutions Ukraine. Materials methods. An anonymous online survey was conducted between November 11 December 20, 2024, involving 146 specialists (50 pharmacists 96 physicians) responsible various across The reliability differences frequency certain features analyzed using chi-square test. Results. study noted decrease overall consumption, adherence documenting prescriptions medical records, reduction duration therapy, shorter durations intravenous antibiotic administration. Pharmacists were significantly more likely than physicians report use reserve group drugs (85.7% vs. 55.2%, p=0.0035). Insufficient microbiological diagnostic support reported 61% respondents, communication coordinating therapy 44.5%, difficulties teamwork development 35.6%, shortages 28.8%, lack time 23.3%, inadequate administrative 20.5%, insufficient regulatory 19.9%, creating standard operating procedures (SOPs) 19.2%. Training prescribers agents most significant intervention 45.9% respondents; 13% cited preauthorization; 8.9% mentioned prospective audit with feedback; 8.2% each optimizing developing SOPs; 2.7% stepwise therapy. Conclusions. Three main groups identified: material resources, prioritization measures hospital administration, socio-psychological barriers that hinder communication. antibiotics predominantly achieved through passive interventions.
Язык: Английский
Процитировано
0
BMC Infectious Diseases, Год журнала: 2024, Номер 24(1)
Опубликована: Апрель 26, 2024
Overuse of antibiotics is a key driver antimicrobial resistance (AMR) world-wide. Malawi continues to report rising cases AMR among both in-patients and out-patients. We investigated antibiotic use patterns patients with suspected first line treatment failure at Rumphi District Hospital, Malawi.
Язык: Английский
Процитировано
3
Revue Scientifique et Technique de l OIE, Год журнала: 2024, Номер 43, С. 168 - 176
Опубликована: Авг. 30, 2024
Misuse and overuse of antimicrobials in livestock production are identified as drivers for antimicrobial resistance (AMR). To improve decision-making concerning health, it is important to understand the impact AMR aquaculture, within beyond farm level, well expenditure on use (AMU). Such understanding provides grounds systematic disease prioritisation establishes a baseline value different strategies mitigate animal health problems monitoring evaluation those strategies. Yet limited data availability quality surrounding AMU create barriers furthering knowledge such impact. These constraints also more prevalent contexts that lack necessary resources develop maintain centralised collection collation systems. Even regions with robust systems place, limitations remain, impacts remain unclear. Additionally, current research funding have been less focused primary collection, adding further filling void reducing global AMU/AMR gap. work around scarcity leverage previous ongoing efforts, vital gain comprehensive people, projects consortia dedicated topic AMU/AMR.
Язык: Английский
Процитировано
2
CABI One Health, Год журнала: 2024, Номер unknown
Опубликована: Апрель 30, 2024
Abstract Despite a gendered approach being increasingly applied across global health challenges, this has been notable oversight in antimicrobial resistance (AMR) research. Failing to consider the complexity of human behaviours and roles healthcare, animal production, environmental settings compromises programmatic effectiveness sustainability, while risking entrenching or widening existing social disparities. Research demonstrates how gender norms influence health-related various sectors, from accessing healthcare livestock rearing, with strong implications for stewardship zoonotic disease transmission. The sparse literature connecting investigating gender, equity AMR – especially One Health context hampers our ability comprehensively address issue. responsibility is however shared. This commentary advocates funders propel inclusion equity-focused perspectives research set expectations landscapes, thus fostering more equitable landscape strengthening strategies against AMR. We outline rationale recommendations other support an ecosystem that supports as common aspect not exception. impact statement While recognised challenge encompassing humans, animals, plants environment, sector-specific cross-sectoral solutions needed too often lack multidisciplinary holistic response challenge. To date, largely biomedical, limited investigation including on its interplay factors drive different such community farm settings. Intentionally integrating analysis informs design implementation supportive funding opportunities, will help build evidence base projects public programs should integrate disparities spectrum. ensure contextually relevant gender-informed sustainable impact.
Язык: Английский
Процитировано
0
Infection Prevention in Practice, Год журнала: 2023, Номер 5(4), С. 100317 - 100317
Опубликована: Ноя. 14, 2023
Язык: Английский
Процитировано
0