Indole-based NNN donor Schiff base ligand and its complexes: Sonication-assisted synthesis, characterization, DNA binding, anti-cancer evaluation and in-vitro biological assay
Bioorganic Chemistry,
Год журнала:
2024,
Номер
146, С. 107281 - 107281
Опубликована: Март 11, 2024
Язык: Английский
Synthesis, characterization, anticancer and antimicrobial studies of metal nanoparticles derived from Schiff base complexes
Inorganic Chemistry Communications,
Год журнала:
2024,
Номер
165, С. 112524 - 112524
Опубликована: Май 11, 2024
Язык: Английский
New Metal Complexes Incorporating Schiff Base Ligand Based on Pyridine Moiety: Synthesis, Spectral Characterization, DFT, Biological Evaluation, and Molecular Docking
Applied Organometallic Chemistry,
Год журнала:
2024,
Номер
39(1)
Опубликована: Окт. 9, 2024
ABSTRACT
A
new
Schiff
base
ligand,
HNMPC
,
was
prepared
and
reacted
with
some
metal
ions,
including
Cu(II),
Ni(II),
Co(II),
Mn(II),
VO(IV).
The
infrared,
electronic,
mass,
electron
spin
resonance,
nuclear
magnetic
thermal
elemental
analysis,
molar
conductance,
susceptibility
measurements
were
used
to
characterize
the
complexes.
ligand
acts
as
a
monoanionic
tridentate
ONO
donor
in
all
complexes,
coordinating
sites
are
C=O
pyridone
C=N,
phenolate
anion.
All
complexes
exhibit
octahedral
configurations,
results
showed
that
ion:ligand
ratio
1:2.
molecular
structural
parameters
of
its
determined
based
on
DFT
level
implemented
Gaussian
09
program
B3LYP/GENECP
method
at
6‐311G(d,p)
basis
set
for
C,
H,
N,
O
atoms
SDD
(Stuttgart/Dresden)
atoms.
theoretical
data
correlated
experimental
results.
Gram‐positive
bacteria,
Gram‐negative
yeast,
fungi
test
current
compounds'
antimicrobial
activity.
Investigating
antitumor
activity
against
HepG2
cell
lines
encouraging
IC
50
values
par
those
cisplatin
.
In
order
determine
affinity
binding
pattern
synthesized
compounds
toward
VEGFR‐2
active
site,
docking
studies
conducted,
data.
Based
obtained
results,
future
work
aimed
synthesize
category
bases
their
derived
from
aminopyridine
derivative
diverse
aldehydes
ketones.
Язык: Английский
Investigation of disulfide-based Schiff base and its mono and binuclear Cu(II) complexes: Green Synthesis, crystal structure analysis, Hirshfeld surface analysis, in-vitro biological assessment, DNA binding studies, and computational studies
Journal of Molecular Structure,
Год журнала:
2025,
Номер
unknown, С. 141997 - 141997
Опубликована: Март 1, 2025
Язык: Английский
Two new cobalt (II) and copper (II) complexes with Azo-azomethine Ligand: Synthesis, Antioxidant and Antibacterial activities, Thermal investigations, DFT calculations, and Molecular docking studies
Journal of Molecular Structure,
Год журнала:
2025,
Номер
unknown, С. 142177 - 142177
Опубликована: Март 1, 2025
Язык: Английский