ChemistrySelect, Год журнала: 2024, Номер 10(1)

Опубликована: Дек. 30, 2024

Abstract The demand for smaller nanomaterials with biocompatible properties has become increasingly imperative in the quest to combat microbial infections and cancer. This requires modifying chemical process. In this investigation, polyvinylpyrrolidone–silver chloride (PVP–AgCl) (NMs) were developed via a sonochemical method involving Ag + sourced from AgNO 3 metal precursor Cl − NaCl, assistance of capping agent PVP. Synthesized NMs characterized using XRD, FTIR, SEM/EDS, DLS TEM. SEM analysis indicated spindle‐like structures star‐shaped formations at edges, whereas TEM showed size ∼24 ± nm. Furthermore, PVP–AgCl exhibited zeta potential approximately −18.34 mV, an average hydrodynamic diameter 127.7 1.287 nm polydispersity index 0.1879. anticancer activity tested against cervical cancer cells (HeLa). addition, toxicity studies fibroblast cell (L929) revealed that demonstrate significant while showing minimal toward L929 cells. antimicrobial was S. aureus E. coli strains. prepared exhibit properties. These findings suggest are used biomedicine coatings applications.

Язык: Английский