Green Chemistry Approach to Ni 2+ , Co 2+ , and Cu 2+ Schiff Base Complexes: Spectroscopic Characterization, Cyclic Voltammetry, Bioactivity Insights and Molecular Docking Investigations DOI Creative Commons
Khlood S. Abou‐Melha

Research Square (Research Square), Год журнала: 2024, Номер unknown

Опубликована: Ноя. 15, 2024

Abstract New Schiff base solid chelates derived from N-(benzol [d] thiazol-2-yl)-3-(2-hydroxybenzylidene) hydrazinyl)-3-oxopropanamide (H2L) as potent ligand and Ni2+, Co2+, Cu2+ metal cations have been prepared through ball milling green chemistry method, represents an environmentally friendly alternative to traditional solvents. The structure synthesized compounds illustrated by elemental analyses, 1H, 13C-NMR, FTIR, UV-visible, ESR, powder XRD, EDX, SEM, MS, thermal analyses (TG, DTG). Also, some computational studies for isolated estimated DFT theory which is a quantum-mechanical atomistic model technique compute extensive variation of properties any kind atomic system. Standard methods used assessment the bioactivity H2L its antimicrobial, antioxidant, cytotoxicity, erythrocyte hemolysis, DNA- binding assess their inhibitory effect. To evaluate affinities analyzed with crystallographic Bcl2 receptor bound DRO (PDB: 2w3l) Molecular Operating Environmental module (MOE) was used. Lastly, electrochemical behavior copper (II) ion were studied investigate chelation in solution cyclic voltammetry absence/presence at 291.15 K mixed solvent dimethyl sulfoxide water.

Язык: Английский

New chelating quinoxalyl hydrazone derivative, as tridentate ligand for complexation with Co(II), Ni(II), and Cu(II) ions. Development of antitumor, antimicrobial, and DNA reactivity DOI
Mohamed Shaker S. Adam, M. J. A. Abualreish, Amr Negm

и другие.

Inorganic Chemistry Communications, Год журнала: 2024, Номер 166, С. 112620 - 112620

Опубликована: Май 25, 2024

Язык: Английский

Процитировано

5
Organotin(IV) complexes: Emerging Frontiers in anticancer therapeutics and bioimaging applications DOI
Yang Zi, Fahad A. Alhumaydhi, Waleed Al Abdulmonem

и другие.

Coordination Chemistry Reviews, Год журнала: 2025, Номер 534, С. 216582 - 216582

Опубликована: Март 13, 2025

Язык: Английский

Процитировано

0
Synthesis and Characterization of a Fluorinated Schiff Base from Benzimidazole and Its Metal Complexes for Antimicrobial and UV-Protective Cotton Fabrics DOI Open Access
Ahmed N. Al‐Hakimi, Tahani M. Alresheedi, Reema A. Albarrak

и другие.

Coatings, Год журнала: 2025, Номер 15(4), С. 380 - 380

Опубликована: Март 24, 2025

Due to the lack of UV-protective properties for cotton textiles and potential cause microbes their users, we synthesized benzimidazole Schiff base derivative (BZI) namely N-((1H-benzo[d]imidazol-2-yl)methyl)-1-(4-fluorophenyl)methanimine V(III), Fe(III), Co(II), Ni(II), Cu(II) complexes as UV protection antimicrobial agents textile. Several techniques investigated these compounds: 1H, 13C NMR, IR, UV–Vis, elemental analysis, DTA, TGA. The ligand behaved a bidentate ligand. prepared its are used treat fabrics (CFs) by immersing fabric in solution samples under ultrasonic. treated were using IR SEM-EDX analysis. UPF values obtained. results showed that with Fe(III) had excellent 50+. disc diffusion method evaluated fabric’s activity. antifungal activities CFs demonstrated Co(II)-BZI-CF was active on C. albicans an inhibition zone 12 mm, while other inactive A. flavus. V(III)-BZI-CF Fe(III)-BZI-CF no activity against S. aureus E. coli bacteria gave between 10 17 mm. Unlike previous studies primarily focused either or metal separately, this research integrates both functionalities synthesizing applying them textiles, demonstrating enhanced selective

Язык: Английский

Процитировано

0
Schiff baseAlkyne precursor for1,2,3-Triazole functionalized organosiliconas a PotentialSensor for Zn(II)andAntioxidantActivity DOI
Gurjaspreet Singh,

Jigmat Stanzin,

Sumesh Khurana

и другие.

Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy, Год журнала: 2024, Номер 316, С. 124319 - 124319

Опубликована: Апрель 21, 2024

Язык: Английский

Процитировано

3
New Metal Complexes Incorporating Schiff Base Ligand Based on Pyridine Moiety: Synthesis, Spectral Characterization, DFT, Biological Evaluation, and Molecular Docking DOI Open Access
Nesma Salah, Omima M.I. Adly, Magdy A. Ibrahim

и другие.

Applied Organometallic Chemistry, Год журнала: 2024, Номер 39(1)

Опубликована: Окт. 9, 2024

ABSTRACT A new Schiff base ligand, HNMPC , was prepared and reacted with some metal ions, including Cu(II), Ni(II), Co(II), Mn(II), VO(IV). The infrared, electronic, mass, electron spin resonance, nuclear magnetic thermal elemental analysis, molar conductance, susceptibility measurements were used to characterize the complexes. ligand acts as a monoanionic tridentate ONO donor in all complexes, coordinating sites are C=O pyridone C=N, phenolate anion. All complexes exhibit octahedral configurations, results showed that ion:ligand ratio 1:2. molecular structural parameters of its determined based on DFT level implemented Gaussian 09 program B3LYP/GENECP method at 6‐311G(d,p) basis set for C, H, N, O atoms SDD (Stuttgart/Dresden) atoms. theoretical data correlated experimental results. Gram‐positive bacteria, Gram‐negative yeast, fungi test current compounds' antimicrobial activity. Investigating antitumor activity against HepG2 cell lines encouraging IC 50 values par those cisplatin . In order determine affinity binding pattern synthesized compounds toward VEGFR‐2 active site, docking studies conducted, data. Based obtained results, future work aimed synthesize category bases their derived from aminopyridine derivative diverse aldehydes ketones.

Язык: Английский

Процитировано

2
Synthesis, Characterization, Biological Potency, and Molecular Docking of Co2+, Ni2+, and Pd2+ Complexes Derived From Carbohydrazone Ligand and Its Application in Dye Removal DOI

Mohab A. El‐Helw,

Usama El‐Ayaan,

Yasmeen G. Abou El‐Reash

и другие.

Applied Organometallic Chemistry, Год журнала: 2024, Номер unknown

Опубликована: Окт. 16, 2024

ABSTRACT As a result of the Schiff base condensation reaction between carbohydrazide and 4‐aminoacetophenone, novel HL ligand [( Z )‐ N ′‐(( )‐1‐(4‐aminophenyl)ethylidene)‐2‐(1‐(4‐aminophenyl)ethylidene)hydrazine‐1‐carbohydrazide] three coordination compounds were successfully obtained with formulas [Co 2 (L)(Cl) 3 (H O)].Cl, [Ni O) ].Cl.H O, [Pd (HL)(Cl)(H structures analyzed using analytical spectroscopic techniques such as Fourier‐transform infrared (FT‐IR), NMR, UV–Vis, molar conductivity, elemental analysis, magnetic susceptibility measurements. Additionally, thermal stabilities, kinetic, thermodynamic parameters estimated utilizing thermogravimetric analysis. The confirmed through quantum chemical computations. antioxidant, anticancer, antimicrobial biological efficacies its metal chelates assessed. shows optimistic results an while Co 2+ Pd complexes showed highest activities. DNA binding affinity cleavage isolated evaluated. Furthermore, fluorescence spectrum in absence presence was recorded order to investigate interaction along limit detection. Another application this work is removal methylene blue crystal violet dyes from wastewater reusability, inventive synthesis cellulose‐based material “LDC” base.

Язык: Английский

Процитировано

1
Synthesis of a pincer bis-hydrazone chelator for coordination, thermal, electrochemical, and biological investigations with CuII, CoII, and HgII DOI

Afnan I. Gomaa,

Esam A. Gomaa, Rania Zaky

и другие.

Journal of Molecular Liquids, Год журнала: 2024, Номер 408, С. 125375 - 125375

Опубликована: Июль 2, 2024

Язык: Английский

Процитировано

0
Green Chemistry Approach to Ni 2+ , Co 2+ , and Cu 2+ Schiff Base Complexes: Spectroscopic Characterization, Cyclic Voltammetry, Bioactivity Insights and Molecular Docking Investigations DOI Creative Commons
Khlood S. Abou‐Melha

Research Square (Research Square), Год журнала: 2024, Номер unknown

Опубликована: Ноя. 15, 2024

Abstract New Schiff base solid chelates derived from N-(benzol [d] thiazol-2-yl)-3-(2-hydroxybenzylidene) hydrazinyl)-3-oxopropanamide (H2L) as potent ligand and Ni2+, Co2+, Cu2+ metal cations have been prepared through ball milling green chemistry method, represents an environmentally friendly alternative to traditional solvents. The structure synthesized compounds illustrated by elemental analyses, 1H, 13C-NMR, FTIR, UV-visible, ESR, powder XRD, EDX, SEM, MS, thermal analyses (TG, DTG). Also, some computational studies for isolated estimated DFT theory which is a quantum-mechanical atomistic model technique compute extensive variation of properties any kind atomic system. Standard methods used assessment the bioactivity H2L its antimicrobial, antioxidant, cytotoxicity, erythrocyte hemolysis, DNA- binding assess their inhibitory effect. To evaluate affinities analyzed with crystallographic Bcl2 receptor bound DRO (PDB: 2w3l) Molecular Operating Environmental module (MOE) was used. Lastly, electrochemical behavior copper (II) ion were studied investigate chelation in solution cyclic voltammetry absence/presence at 291.15 K mixed solvent dimethyl sulfoxide water.

Язык: Английский

Процитировано

0